CALCIUM SANDOZ C 500MG INJ

CALCIUM SANDOZ C 500MG INJ

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  • Manufacturer LOCAL PURCHASE
  • Generic Name

    Calcium gluconate, Calcium lactobionate

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Calcium gluconate and calcium lactobionate are calcium salts used as calcium replacement therapies. When administered, these compounds dissociate into calcium ions (Ca2+) and their respective anions. Calcium ions play a crucial role in various physiological processes, including bone mineralization, muscle contraction, nerve impulse transmission, and blood coagulation. They exert their effects by binding to specific calcium-binding sites on enzymes, ion channels, and receptors, thereby modulating cellular signaling pathways and physiological functions. Calcium ions are particularly important in maintaining the integrity of cell membranes, regulating intracellular processes, and facilitating the release of neurotransmitters and hormones. By replenishing calcium levels, these calcium salts help restore normal cellular function and counteract conditions associated with calcium deficiency or hypocalcemia.

  • Ingredients

    Calcium gluconate, Calcium lactobionate

  • Drug Class

    Calcium salts.

  • Dosage Form

    Injection

  • Uses

    The following are the uses of Calcium gluconate, Calcium lactobionate Injection:

    • Used for treating calcium deficiencies and conditions requiring calcium supplementation, such as hypocalcemia and hypoparathyroidism.
    • Used for managing cardiac arrhythmias and stabilizing heart function.
    • Used for treating hyperkalemia by helping to lower potassium levels in the blood.
    • Used for preventing and treating calcium deficiencies during pregnancy, breastfeeding, and in infants.
    • Used for replenishing calcium stores in cases of calcium depletion or malabsorption.
    • Used for managing calcium levels during surgery or in intensive care settings.
    • Used for providing calcium support in various medical conditions such as rickets and osteomalacia.
  • In case of Overdose

    In the event of an overdose of Calcium Gluconate or Calcium Lactobionate Injection, it is important to monitor for symptoms such as nausea, vomiting, constipation, and in severe cases, cardiac arrhythmias. Promptly seek medical assistance and provide healthcare professionals with information regarding the product, the amount ingested, and the time of overdose. Treatment may involve supportive care, managing symptoms, and ensuring proper hydration.

  • Missed Dose

    In the case of a missed dose of Calcium Gluconate, it is generally recommended to administer the missed dose as soon as possible, but if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. For Calcium Lactobionate Injection, if a dose is missed, administer it as soon as you remember, however, if it is close to the time for the next dose, skip the missed dose and resume the regular dosing frequency. It is crucial to maintain a consistent dosing routine to ensure optimal calcium levels.

  • How To Use

    To administer Calcium Gluconate and Calcium Lactobionate Injection, mix the contents of the vial with the appropriate amount of sterile water for injection as directed by your healthcare professional, gently swirl the vial to dissolve the powder completely, and then use a sterile syringe to withdraw the prescribed dose before injecting it intravenously over a controlled period as instructed by your medical team.

  • When Not to Use

    Following are the conditions/situations when Calcium gluconate or Calcium lactobionate Injection should not be used:

    • Allergy or hypersensitivity to calcium gluconate, calcium lactobionate, or any of the excipients in the injection.
    • Patients with hypercalcemia (high levels of calcium in the blood) or conditions causing elevated calcium levels, such as hyperparathyroidism or vitamin D toxicity.
    • Patients with severe kidney disease or impaired kidney function, as calcium excretion may be compromised.
    • Patients with ventricular fibrillation, a type of abnormal heart rhythm, as calcium administration can worsen this condition.
    • Patients with digitalis toxicity, as calcium can increase the risk of cardiac arrhythmias.
    • Conditions associated with high blood calcium levels, such as sarcoidosis or hypervitaminosis D.
    • Patients with severe dehydration or hypovolemia, as calcium administration may worsen these conditions.
    • Patients with a history of calcium-containing kidney stones or nephrocalcinosis.
    • Not recommended for patients with cardiac arrest due to calcium channel blocker overdose.
    • Should not be used in patients with severe heart failure or cardiogenic shock.
  • Side Effects

    The side effects of Calcium gluconate and Calcium lactobionate Injection may include:

    • Nausea and vomiting.
    • Constipation or diarrhea.
    • Dry mouth or increased thirst.
    • Muscle or bone pain.
    • Fatigue and weakness.
    • Allergic reactions, such as rash, itching, or swelling.
    • Slow heart rate or irregular heartbeat.
    • High calcium levels in the blood, which can lead to confusion, kidney problems, and other complications.
  • Precautions & Warnings

    Following are the precautions and warnings for Calcium gluconate, Calcium lactobionate Injection:

    • This medication should be used with caution in patients with impaired kidney function, as it may require dosage adjustments.
    • It is important to monitor calcium levels regularly during treatment, especially in patients with a history of kidney stones or hypercalcemia.
    • Do not administer intravenously too rapidly, as it may cause cardiac arrhythmias and other serious side effects.
    • Patients with heart disease or a history of cardiac issues should be closely monitored, as calcium can affect heart function.
    • Avoid using this medication in patients with digitalis toxicity, as it may worsen the condition.
    • Elderly patients may be more susceptible to the effects of calcium, so dosage adjustments might be necessary.
    • Inform your healthcare provider if you have a history of allergies or any other medical conditions before using this medication.
  • Drug Interactions

    Following are the drug interactions for Calcium gluconate, Calcium lactobionate Injection:

    • When combined with cardiac glycosides, it may lead to increased risk of cardiac toxicity and arrhythmias.
    • Concomitant use with calcium channel blockers can result in additive cardiac effects and potential hypotension.
    • May reduce the absorption of oral bisphosphonates, so separate administration by at least 2 hours.
    • Thiazide diuretics can increase calcium retention, leading to hypercalcemia when used with calcium supplements.
    • Tetracycline antibiotics may have reduced absorption when taken with calcium gluconate.
    • The effectiveness of quinolone antibiotics might be decreased when used with calcium-containing products.
    • It can interfere with the action of anticoagulants, requiring close monitoring of coagulation parameters.
  • Food Interactions

    Following are the food interactions to consider with Calcium gluconate and Calcium lactobionate Injection:

    • Calcium-rich foods like milk, yogurt, cheese, and leafy green vegetables may be recommended to maintain calcium levels, especially if you have a calcium deficiency.
    • Avoid excessive intake of foods high in oxalic acid (like spinach, rhubarb, and sweet potatoes) or phytic acid (found in whole grains and legumes) as they can bind with calcium and reduce its absorption.
    • Limit sodium intake as sodium can increase calcium excretion, especially in individuals with calcium-related conditions.
    • Ensure adequate hydration, as proper fluid intake is essential for calcium metabolism and kidney function.
    • Avoid high-fiber foods close to the time of injection as they can potentially reduce the absorption of calcium.
    • Alcohol should be consumed in moderation, as excessive alcohol intake can affect bone health and calcium metabolism.
    • Caffeine intake should be monitored, as high caffeine consumption may interfere with calcium absorption and increase calcium excretion.
    • Follow any dietary recommendations provided by your healthcare professional, especially if you have conditions like kidney disease, osteoporosis, or parathyroid disorders.
  • Storage/Disposal

    Calcium gluconate and Calcium lactobionate Injection storage and disposal should be handled with care. Store the injections in a cool, dry place, preferably at room temperature between 15°C and 30°C (59°F and 86°F), away from direct sunlight and moisture. Keep the vials or ampoules in their original packaging until use to maintain sterility. Do not freeze the injections as it may affect their potency. Dispose of any unused or expired medication responsibly; do not pour it down the drain or flush it. Contact your healthcare provider or pharmacist for guidance on proper disposal methods to ensure environmental safety. Keep all medications out of the reach of children and pets to prevent accidental exposure.

  • Quick Tips, if any

    Following are the quick tips for Calcium Gluconate and Calcium Lactobionate Injection:

    • Administer the injection under medical supervision for safe and effective use.
    • Ensure proper dosage calculation based on individual needs and medical condition.
    • Slow intravenous injection is recommended to minimize discomfort and adverse effects.
    • Monitor blood calcium levels regularly during treatment to prevent calcium overload.
    • Report any signs of allergic reactions, such as rash or difficulty breathing, immediately.
    • Do not mix with other medications unless directed by a healthcare professional.
    • Store the injection as directed on the package to maintain its stability and efficacy.
    • Discard any unused or expired medication safely to prevent misuse.

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