Calm (30mg) 30 Capsules

Calm (30mg) 30 Capsules

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  • Manufacturer Wilshire Labs (Pvt.) Ltd.
  • Generic Name Temazepam

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Temazepam, a benzodiazepine medication, exerts its therapeutic effects primarily through its interaction with the gamma-aminobutyric acid (GABA) receptors in the brain. By binding to specific benzodiazepine receptors, Temazepam enhances the inhibitory effects of GABA, a neurotransmitter that plays a crucial role in regulating neuronal excitability. This potentiation of GABA's action leads to an increase in chloride ion influx, causing hyperpolarization of the neuronal membrane. As a result, the central nervous system becomes less responsive to external stimuli, leading to the sedative, anxiolytic, and muscle relaxant properties associated with Temazepam. This mechanism of action helps to calm overactive neurons, promoting relaxation, reducing anxiety, and facilitating sleep, making it particularly effective in the treatment of insomnia and other sleep-related disorders.

  • Ingredients

    Temazepam
  • Drug Class

    Benzodiazepine sedative.

  • Dosage Form

    Capsule

  • Uses

    The following are the uses of Temazepam 30mg Capsule:

    • Used for treating insomnia and other sleep disorders, helping individuals fall asleep and stay asleep.
    • Used for anxiety-related sleep disturbances, providing relief from anxious thoughts and promoting relaxation.
    • Used for managing sleep issues in individuals with mental health conditions, supporting overall well-being.
    • Used for resetting the sleep cycle, aiding those with irregular sleep patterns or jet lag.
    • Used for elderly patients with sleep difficulties, offering a gentle and effective solution.
    • Used for short-term treatment, ensuring a limited duration of use for sleep problems.
    • Used for improving sleep quality, enhancing overall restfulness and daytime alertness.
  • In case of Overdose

    In the case of an overdose of Temazepam 30mg Capsules, immediate medical attention is necessary. Symptoms may include severe drowsiness, confusion, and impaired coordination. In more serious cases, respiratory depression, low blood pressure, and even loss of consciousness can occur. Prompt treatment can involve inducing vomiting or administering activated charcoal to prevent further absorption. Medical professionals should be informed about the quantity ingested to provide appropriate care and ensure the best possible outcome.

  • Missed Dose

    In the case of a missed dose of Temazepam 30mg Capsule, it is important to follow these guidelines If you miss a dose, take it as soon as you remember, but only if there is sufficient time left before your next scheduled dose. Do not double the dose to make up for a missed one. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. It is essential to maintain a consistent medication routine, but if you frequently miss doses, inform your healthcare provider for further advice on managing your medication.

  • How To Use

    To take Temazepam 30mg Capsule, swallow the capsule whole with a glass of water, preferably at bedtime, following the dosage instructions provided by your healthcare professional, ensuring you do not exceed the prescribed amount.

  • When Not to Use

    Here is the information regarding the conditions when Temazepam 30mg Capsule should not be used:

    • Do not use Temazepam if you have a known allergy or hypersensitivity to the drug or any of its components.
    • Contraindicated in patients with a history of severe respiratory depression or asthma.
    • Should not be taken by individuals with acute narrow-angle glaucoma.
    • Not recommended for patients with severe liver impairment or hepatic disease.
    • Avoid using Temazepam if you have sleep apnea or other respiratory problems.
    • Contraindicated in patients with a history of severe depression or suicidal thoughts/attempts.
    • Do not consume alcohol while taking Temazepam as it can worsen the side effects.
    • Should not be used in patients with myasthenia gravis.
    • Not suitable for individuals with a history of drug or substance abuse.
    • Avoid driving or operating heavy machinery as Temazepam can cause drowsiness and impaired coordination.
  • Side Effects

    The side effects of Temazepam 30mg Capsule may include:

    • Drowsiness or sedation
    • Dizziness
    • Unsteadiness or loss of balance
    • Confusion or memory problems
    • Slurred speech
    • Fatigue or weakness
    • Muscle coordination problems
    • Allergic reactions (skin rash, itching, swelling)
  • Precautions & Warnings

    Following are the precautions and warnings:

    • Temazepam 30mg Capsule should not be used in patients with a known or suspected allergy to benzodiazepines or any of its components.
    • It is recommended to exercise caution in patients with a history of respiratory problems, as it can suppress breathing.
    • Patients with liver or kidney impairment may require dosage adjustments and should be monitored closely.
    • Temazepam may cause drowsiness and impair judgment; patients should avoid driving, operating machinery, or activities requiring full alertness.
    • Alcohol and other central nervous system depressants should be avoided as they can enhance the sedative effects of Temazepam.
    • This medication is not recommended for use in children and adolescents under 18 years of age.
    • Pregnant and breastfeeding women should consult their doctor, as Temazepam may cause harm to the fetus or infant.
    • Do not increase the dosage or frequency without medical advice, as it may lead to dependence and withdrawal symptoms.
  • Drug Interactions

    Following are the drug interactions for Temazepam 30mg Capsule:

    • Alcohol and other central nervous system (CNS) depressants, such as opioids or antipsychotics, can increase the sedative effects of Temazepam, leading to severe drowsiness and respiratory depression.
    • Strong CYP3A4 inhibitors like ketoconazole can significantly increase Temazepam levels, resulting in enhanced side effects.
    • CYP3A4 inducers (e.g., rifampicin) may decrease the effectiveness of Temazepam by increasing its metabolism.
    • Antidepressants (SSRIs, TCAs) and other sedating medications can potentiate the CNS effects of Temazepam.
    • The effectiveness of Temazepam may be reduced by strong CYP2C19 inducers like rifampicin.
    • Anticonvulsants like phenytoin may decrease Temazepam levels, reducing its therapeutic effect.
    • Temazepam may increase the concentration of other drugs metabolized by CYP3A4, such as midazolam, potentially leading to adverse effects.
  • Food Interactions

    Following are the food interactions for Temazepam 30mg Capsule:

    • Alcohol should be strictly avoided as it can enhance the sedative effects of Temazepam, leading to increased drowsiness and impaired coordination.
    • Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Temazepam, potentially increasing its concentration in the blood and prolonging its effects.
    • Fatty foods may slightly delay the absorption of Temazepam, but this effect is generally not clinically significant.
    • Caffeine-rich beverages like coffee and energy drinks should be limited as they can counteract the sedative effects of Temazepam, making it less effective for sleep disorders.
    • Heavy meals close to bedtime may interfere with the absorption of Temazepam, potentially affecting its efficacy. It is advisable to take the medication on an empty stomach or with a light snack.
    • Avoid foods containing St. John's Wort as it can reduce the effectiveness of Temazepam by influencing the body's neurotransmitters.
    • There is no known interaction with dairy products, but it's best to consult your pharmacist for personalized advice.
    • Always follow the advice of your healthcare provider regarding dietary restrictions or recommendations while taking Temazepam.
  • Storage/Disposal

    Temazepam 30mg capsules should be stored in a secure and controlled environment, preferably in a locked cabinet or a designated medication storage area. Keep the capsules in their original packaging or container, ensuring the container is tightly sealed to maintain their integrity. Store them at room temperature, away from excessive heat, direct sunlight, and moisture, as these conditions can degrade the medication. It is crucial not to store them in the bathroom or near the kitchen sink to prevent exposure to humidity. Always check the expiration date, and do not use the capsules beyond this date. When disposing of unused or expired Temazepam capsules, do not flush them down the toilet or throw them into the trash. Instead, follow local guidelines for medication disposal or consult a pharmacist who can provide guidance on safe disposal methods, ensuring they are kept out of the reach of children and pets.

  • Quick Tips, if any

    Following are the quick tips for Temazepam 30mg Capsule:

    • Take the capsule as directed by your doctor, typically just before bedtime.
    • Swallow the capsule whole with a glass of water, do not crush or chew.
    • Ensure you have a full 7-8 hours to dedicate to sleep after taking the medication.
    • Avoid alcohol and other sedatives while using this medication.
    • Inform your doctor about all medications you are taking to prevent potential interactions.
    • Store the capsules in a cool, dry place, away from direct sunlight.
    • Do not drive or operate machinery until you know how this medicine affects you.
    • Seek medical advice if you experience any unusual or severe side effects.

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