CALMIN INJ 600 500ML

This injection formulation contains a combination of amino acids, magnesium oxides and hydroxides, nicotinamide (vitamin B3), and potassium chloride, each serving a specific role to support bodily functions. Amino acids are the building blocks of proteins, and in this injection, they provide essential nutrients that support tissue repair, muscle function, and overall cellular health. Magnesium oxides and hydroxides are used to correct magnesium deficiencies, supporting muscle and nerve function, as well as maintaining normal blood pressure. Nicotinamide, a form of vitamin B3, helps in energy production, supporting cellular metabolism and promoting healthy skin. Potassium chloride helps maintain proper electrolyte balance, supports nerve function, and regulates fluid balance in the body. Together, these components help maintain hydration, restore essential nutrients, and support overall metabolic functions.

Amino Acids 50 g, Magnesium Oxides and Hydroxides[ 0.477 g/L], Nicotinamide[ 60 mg/L], Potassium Chloride[ 1.863 g/L]

Parenteral nutrition.

Injection

The following are the uses of Amino Acids 50 g, Magnesium Oxides and Hydroxides[ 0.477 g/L], Nicotinamide[ 60 mg/L], Potassium Chloride[ 1.863 g/L] Injection:

• Used for providing essential amino acids to support protein synthesis and muscle growth.
• Used as a source of magnesium to promote nerve and muscle function, bone health, and enzyme activity.
• Contains nicotinamide (vitamin B3) for energy metabolism and maintaining healthy skin and nervous system function.
• Used for nutritional support in patients with amino acid deficiencies or malabsorption issues.
• Provides a balanced combination of nutrients for various medical and research applications.

In the case of an overdose of Amino Acids 50 g, Magnesium Oxides, and Hydroxides [0.477 g/L], Nicotinamide [60 mg/L], and Potassium Chloride [1.863 g/L] Injection, immediate medical attention is required. Symptoms may include nausea, vomiting, diarrhea, abdominal pain, and in severe cases, kidney damage or respiratory distress. It is essential to contact a healthcare professional or poison control center for guidance on managing the specific effects of these substances.

In the case of a missed dose of Amino Acids 50 g, administer the missed dose as soon as possible, and then adjust subsequent doses accordingly. For Magnesium Oxides and Hydroxides [0.477 g/L], Nicotinamide [60 mg/L], and Potassium Chloride [1.863 g/L] Injection, if a dose is missed, take the missed dose as soon as possible and continue with the regular schedule. If it is close to the time of the next dose, skip the missed dose and resume the regular dosing schedule.

To prepare and administer the injection, dissolve the contents of the Amino Acids 50 g sachet in the provided solvent, then add Magnesium Oxides and Hydroxides (0.477 g/L), Nicotinamide (60 mg/L), and Potassium Chloride (1.863 g/L) to the solution. Mix thoroughly until all components are fully dissolved, ensuring the solution is clear and free from particles.

Following are the conditions or situations when Amino Acids, Magnesium Oxides and Hydroxides, Nicotinamide, and Potassium Chloride Injection should not be used:

• Allergy or hypersensitivity to any of the components in the injection, including specific amino acids, magnesium, nicotinamide, or potassium chloride.
• Patients with severe kidney disease or impaired kidney function, as these components need to be cleared by the kidneys.
• Individuals with hypermagnesemia (high levels of magnesium in the blood) or conditions that retain magnesium, such as severe renal failure or heart block.
• Patients with severe liver disease, as the metabolism and clearance of some components may be affected.
• Conditions that require careful monitoring of fluid and electrolyte balance, such as heart failure or severe renal impairment, as the injection may alter these balances.
• Individuals with a history of allergic reactions to similar injections or medications.
• Patients with conditions that require restricted potassium intake, such as Addison's disease or severe renal failure.
• Should not be used in patients with a history of gastrointestinal ulcers or bleeding, as nicotinamide may worsen these conditions.

The side effects of Amino Acids 50 g, Magnesium Oxides and Hydroxides, Nicotinamide, and Potassium Chloride Injection may include:

• Nausea and vomiting
• Diarrhea or constipation
• Abdominal pain or cramps
• Skin irritation or rash at the injection site
• Muscle weakness or twitching
• Increased heart rate or palpitations
• Dizziness or lightheadedness
• Magnesium toxicity (in cases of excessive use or impaired kidney function)

Following are the precautions and warnings for Amino Acids, Magnesium Oxides and Hydroxides, Nicotinamide, and Potassium Chloride Injection:

• This medication should be administered under medical supervision due to the potential for electrolyte imbalances and metabolic complications.
• Patients with kidney disease or kidney failure should use with caution, as the magnesium and potassium content may need to be adjusted.
• Diabetic patients should be aware that Nicotinamide may affect blood sugar levels.
• Do not use if you have a known allergy to any of the ingredients, especially amino acids or magnesium compounds.
• Avoid if you have a history of gastrointestinal blockages or conditions like paralytic ileus, as magnesium can slow bowel movements.
• This medication may cause injection site reactions; seek medical attention if redness, swelling, or pain persists.
• Patients with heart disease, especially those with irregular heart rhythms, should use with caution due to the potassium content.
• Infants and elderly individuals may require closer monitoring due to the potential for magnesium toxicity.

Following are the drug interactions for Amino Acids, Magnesium Oxides, Hydroxides, Nicotinamide, and Potassium Chloride Injection:

• It may interact with other medications containing amino acids, potentially leading to imbalances or reduced effectiveness.
• Magnesium can affect the absorption of certain antibiotics, such as quinolones and tetracyclines, and may require dosage adjustments.
• Antacids containing magnesium may decrease the absorption of nicotinamide, so separate administration is recommended.
• Potassium-sparing diuretics and angiotensin-converting enzyme (ACE) inhibitors can increase potassium levels when used with this injection, requiring close monitoring.
• NSAIDs and potassium-containing medications may increase the risk of hyperkalemia, necessitating regular potassium level checks.
• Use with caution in patients taking cardiac glycosides, as it may enhance the effects of these drugs and increase the risk of toxicity.
• Amino acids may influence the metabolism of certain medications, requiring dose adjustments to maintain therapeutic levels.

Following are the food interactions for Amino Acids 50 g, Magnesium Oxides and Hydroxides, Nicotinamide, and Potassium Chloride Injection:

• Avoid consuming high-protein foods like meat, fish, eggs, and dairy products simultaneously as the injection, as they can interfere with the absorption of amino acids, potentially reducing the effectiveness of the medication.
• Maintain a balanced diet rich in whole grains, fruits, and vegetables to ensure a steady supply of essential nutrients and support overall health during treatment.
• Limit or avoid the consumption of foods high in magnesium, such as spinach, almonds, and avocados, as excessive magnesium intake may lead to diarrhea and affect the balance of other minerals.
• Nicotinamide may interact with high-fat meals, so it's best to avoid consuming fatty foods shortly before or after the injection to ensure optimal absorption.
• Potassium-rich foods like bananas, oranges, and potatoes should be consumed in moderation to maintain a balanced potassium level, as excessive potassium intake may lead to hyperkalemia.
• Avoid excessive salt intake, as it can affect the balance of electrolytes, including potassium, in the body.
• Stay well-hydrated by drinking adequate water to support the distribution and elimination of the medication's components.
• Consult a healthcare professional for personalized dietary advice, especially if you have specific dietary restrictions or health conditions.

Storage and disposal of Amino Acids 50 g, Magnesium Oxides and Hydroxides [0.477 g/L], Nicotinamide [60 mg/L], and Potassium Chloride [1.863 g/L] Injection require specific attention to ensure safety and maintain integrity. Store this medication in a cool, dry environment, maintaining a consistent room temperature. Keep the injection away from direct sunlight, heat sources like stoves or radiators, and moisture to prevent degradation. Always seal the container tightly after use to prevent contamination. Check the expiration date regularly, and dispose of any unused or expired injections following proper guidelines. Avoid flushing or pouring it down the drain; consult a pharmacist or healthcare provider for appropriate disposal methods. Keep this medication away from children to prevent accidental ingestion.

Following are the quick tips for Amino Acids 50 g, Magnesium Oxides and Hydroxides[ 0.477 g/L], Nicotinamide[ 60 mg/L], Potassium Chloride[ 1.863 g/L] Injection:

• Administer the injection under medical supervision and as directed by your healthcare provider.
• Ensure proper dosage and duration as prescribed.
• Do not inject if the solution appears cloudy or contains particles.
• Use a sterile needle and syringe for each injection.
• Rotate injection sites to minimize skin irritation.
• Dispose of used needles and syringes safely in designated sharps containers.
• Store the injection as directed on the package, away from direct sunlight and moisture.
• Keep a record of your injection schedule and inform your healthcare provider of any concerns.