CANDEREL POUCH 80G

CANDEREL POUCH 80G

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  • Manufacturer SEARLE PHARMACEUTICALS (PVT.) LTD.
  • Generic Name

    Aspartame

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Rs. 410.0
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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Aspartame is an artificial sweetener that is composed of two amino acids, aspartic acid and phenylalanine. Its mechanism of action involves taste receptor modulation. When aspartame is consumed, it is broken down in the small intestine into its constituent amino acids and a small amount of methanol. These amino acids are then absorbed into the bloodstream. The sweetness of aspartame is a result of its ability to bind to and activate sweet taste receptors on the tongue. The specific mechanism involves the interaction of aspartame with G-protein coupled receptors, particularly the TAS1R2/TAS1R3 heterodimer, which triggers a signaling cascade that leads to the perception of sweetness. Aspartame is approximately 200 times sweeter than sugar, allowing for a very small amount to provide a significant sweet taste.

  • Ingredients

    Aspartame

  • Drug Class

    Sweetener.

  • Dosage Form

    Sachet

  • Uses

    The following are the uses of Aspartame Sachet:

    • Used for sweetening beverages, including coffee, tea, and soft drinks.
    • Used for cooking and baking as a sugar substitute.
    • Used for enhancing the flavor of yogurt, oatmeal, and cereals.
    • Used for creating sugar-free desserts and confectionery.
    • Used for managing blood sugar levels in diabetic diets.
    • Used for reducing overall calorie intake for weight management.
    • Used for providing a sweet taste without the negative effects of sugar.
    • Used for oral health, as it doesn't contribute to tooth decay.
  • In case of Overdose

    In the case of an overdose of Aspartame Sachet, individuals may experience a range of symptoms. These can include headaches, dizziness, and nausea, which are common side effects of excessive aspartame consumption. More severe reactions might involve seizures, rapid heart rate, and confusion. It is important to seek medical advice if you suspect an overdose, as healthcare professionals can provide guidance and treatment to manage these symptoms effectively.

  • Missed Dose

    In the case of a missed dose of Aspartame Sachet, it is generally advised to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It's important not to double the dose to make up for a missed one, as this could lead to excessive consumption of aspartame. If you frequently miss doses, consider setting reminders or alarms to help you stay on track with your medication schedule.

  • How To Use

    To use Aspartame Sachet, simply open the sachet and pour the contents into your beverage or sprinkle it directly onto your food, stirring well to dissolve it completely before consumption.

  • When Not to Use

    Here are the situations or conditions when Aspartame Sachet should not be used:

    • Not recommended for individuals with a known hypersensitivity or allergy to aspartame or any of its components.
    • Should be avoided by people with a rare genetic disorder called phenylketonuria (PKU), as they cannot properly metabolize phenylalanine, an amino acid present in aspartame.
    • Contraindicated in people with a condition called phenylketonuria-like hyperphenylalanine, where they have elevated levels of phenylalanine in the blood.
    • Not suitable for individuals with certain metabolic disorders that affect amino acid metabolism.
    • Should not be consumed if you have a history of seizures or epilepsy, as there are concerns about the potential effects of aspartame on seizure thresholds.
    • Avoid using if you have migraines, as aspartame may trigger or worsen migraine headaches in some individuals.
  • Side Effects

    The side effects of Aspartame Sachet may include:

    • Headaches
    • Dizziness
    • Nausea and vomiting
    • Abdominal pain or cramps
    • Diarrhea
    • Skin rashes or itching
    • Allergic reactions (hives, swelling, difficulty breathing)
    • Changes in mood or behavior, including anxiety and irritability.
  • Precautions & Warnings

    Following are the precautions and warnings for Aspartame Sachet:

    • Not suitable for individuals with phenylketonuria (PKU) as it contains phenylalanine.
    • Not recommended for people with certain rare hereditary problems of protein metabolism.
    • If you have diabetes, aspartame may affect blood sugar levels, so monitor blood glucose levels closely.
    • Should not be used in infants, young children, and pregnant or breastfeeding women without medical advice.
    • If you experience any adverse reactions, such as headaches, dizziness, or digestive issues, discontinue use and consult a healthcare professional.
    • This product is intended as a sweetener and should be used in moderation. Excessive consumption may lead to gastrointestinal discomfort.
    • Keep out of reach of children and pets.
  • Drug Interactions

    Following are the drug interactions for Aspartame Sachet:

    • It is generally safe with most medications, but it may interact with medications that affect phenylalanine metabolism, such as phenylalanine hydroxylase inhibitors.
    • No significant interactions have been reported with common drugs, but concurrent use with medications that lower seizure threshold may require monitoring.
    • Aspartame may interact with antiepileptic drugs, potentially affecting seizure control.
    • It can enhance the absorption of some medications like pentamidine, so dosage adjustments might be necessary.
    • Drugs that affect blood sugar levels, like insulin or diabetes medications, may need monitoring as aspartame can impact glucose regulation.
    • While rare, concurrent use with monoamine oxidase inhibitors (MAOIs) may cause a hypertensive crisis.
    • Exercise caution when combining with alcohol, as it may alter the metabolism of aspartame and affect its breakdown.
  • Food Interactions

    Following are the food interactions for Aspartame Sachet:

    • Aspartame can be used as a tabletop sweetener, so it can be added to various beverages and foods. It is commonly used in coffee, tea, and as a sugar substitute in baking.
    • It is advisable to avoid excessive consumption of aspartame-sweetened foods and drinks, especially those with high-calorie content, as it may lead to weight gain.
    • Aspartame breaks down into components including phenylalanine, which can interact with certain medications like antidepressants and antipsychotics, affecting their effectiveness.
    • Some studies suggest that aspartame may impact the gut microbiome, potentially affecting nutrient absorption and overall gut health.
    • Consuming aspartame with high-protein foods can enhance the sweetness perception, making it a useful alternative sweetener for protein-rich diets.
    • When baking with aspartame, consider adding it towards the end of the mixing process to preserve its sweetness, as prolonged heat exposure may reduce its sweetness intensity.
    • Aspartame-sweetened carbonated drinks can lead to increased acid levels in the mouth, potentially contributing to dental erosion if consumed frequently.
    • People with phenylketonuria (PKU) should strictly avoid aspartame due to their inability to metabolize phenylalanine, a component of aspartame.
  • Storage/Disposal

    Aspartame sachets should be stored in a cool, dry area at room temperature, protected from sunlight and moisture. Keep the sachets in their original packaging, ensuring a tight seal to maintain freshness and prevent contamination. Avoid storing near heat-emitting appliances or in humid environments like bathrooms, as temperature and humidity fluctuations can impact the sachet's contents. Proper disposal is crucial; never flush or pour the contents down the drain. Contact your local waste management facility or pharmacist for guidance on safe disposal methods. Keep aspartame sachets away from children to prevent accidental consumption.

  • Quick Tips, if any

    Following are the quick tips for Aspartame Sachet:

    • Aspartame is a low-calorie sweetener, use it as a sugar substitute in beverages and cooking.
    • Perfect for those managing their weight or blood sugar levels.
    • A tiny amount provides sweetness, so use sparingly.
    • Safe for consumption, but consult a doctor if you're pregnant, breastfeeding, or have a health condition.
    • Store in a cool, dry place, and keep the sachet sealed to maintain freshness.
    • Do not heat or cook aspartame at high temperatures as it may lose its sweetness.
    • Experiment with different brands to find your preferred taste and sweetness level.

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