Canesten (1%) 5g Vaginal Cream

Canesten (1%) 5g Vaginal Cream

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  • Manufacturer Bayer Pakistan (Pvt.) Ltd.
  • Generic Name Clotrimazole

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Description

    Clotrimazole 1% is a powerful antifungal agent utilized in treating skin infections caused by yeast fungi, notably Candida albicans. Its mode of action involves inhibiting the enzyme 14α-methylergosta-8,14,17-trien-3,6-dione synthase (Mets), a critical step in the synthesis of ergosterol, an essential component of the fungal cell membrane. For individuals with athlete's foot (tinea pedis), clotrimazole 1% topical cream is proven to be effective in treating this condition. This medication not only cures most athlete's foot infections but also alleviates the accompanying itch, burning, and cracking. When applied topically to the infected area, clotrimazole 1% is absorbed through the skin, acting locally to prevent the growth and spread of fungus. Despite its effectiveness, it's crucial to use this medication for the full prescribed treatment period, even if symptoms improve, to prevent the infection from returning.

  • Ingredients

    Clotrimazole
  • Drug Class

    Antifungal

  • Dosage Form

    Cream
  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Treatment for fungal infections including ringworm, jock itch, and athlete's foot.
    • Relieving itching associated with skin infections.
    • Used externally as a cream, gel or powder.
    • Available over-the-counter in many countries.
    • Cream is usually applied twice a day for up to four weeks.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • For yeast infection of the skin and surrounding areas, apply clotrimazole 1% cream over the affected area twice a day for up to 4 weeks
    • For fungal infections of the inner ear, use 1 drop of clotrimazole 1% solution in the affected ear twice a day for up to 4 weeks
    • For vaginal yeast infections, use clotrimazole 1% cream or vaginal tablet once a day for up to 7 days
  • In case of Overdose

    An overdose of clotrimazole 1% is unlikely to produce symptoms, but if this happens, it is important to contact an emergency healthcare provider. They will be able to determine if any observations or interventions are required. Informing your healthcare provider of any and all medications and/or supplements you are currently taking, as well as the incident surrounding the overdose, will help them provide you with the best treatment plan. This information is vital to someone getting the correct treatment promptly.

  • Missed Dose

    If you miss a dose of Clotrimazole 1%, it is important to use it as soon as possible. If it is almost time for your next dose, it is recommended to skip the missed dose and continue with your regular schedule. However, do not double up on doses. If you are unsure about whether to take a missed dose, it is best to consult your doctor or pharmacist for advice on the best approach moving forward. It is important to use Clotrimazole 1% as directed and complete the full course of treatment as prescribed by your doctor to ensure the best results and prevent the development of resistance. In summary, it is important to use Clotrimazole 1% as directed, and consult a doctor or pharmacist if you miss a dose. Completing the full course of treatment ensures the best results and prevents resistance.

  • How To Use

    Before using Clotrimazole 1% cream, ensure that you have thoroughly read the prescription label and guidelines provided by your doctor. It is important to follow the specific directions for use to ensure the most effective results.Firstly, apply the cream twice daily, preferably at the same time each day. Clean and dry the affected area before applying the cream, taking care not to shower or bathe immediately after application. Use gentle soap and remember to pat the area dry with a clean towel before applying the cream. For each application, use a thin layer of Clotrimazole 1% cream, no larger than the size of a pea. If required, cover the area with a sterile gauze dressing as per your doctor's instructions. Wash your hands thoroughly after applying the cream unless your hands are also the treatment site. If you miss a dose, apply it as soon as possible. However, if it is almost time for the next application, skip the missed dose and resume the regular schedule. Avoid ingesting the cream as it is only for external use. If you experience any increased irritation, burning, or redness, consult with your doctor or dermatologist immediately. For optimal results, use the cream consistently for as long as prescribed, even if symptoms improve. Full benefits may take several weeks or months to manifest. Follow the instructions provided by your doctor for the best results.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • You are allergic to Clotrimazole, other imidazoles, or any of the other ingredients in the formulation.
    • You have a vaginal yeast infection with unexplained vaginal bleeding or a vaginal infection that has spread to the kidneys or elsewhere in the body.
    • You are using latex or non-latex condoms.
    • You are pregnant or breastfeeding.
    • You have ever had a severe allergic reaction to other antifungal medications.
    • The affected area is infected with bacteria.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Rash.
    • Burning sensation.
    • Itching.
    • Dry, flaky skin.
    • Swelling of the lips, face, or throat.
    • Wheezing, coughing, or difficulty breathing.
    • Severe dizziness.
  • Precautions & Warnings

    Here are some important precautions and warnings for patients to consider:

    • Patients who have had more than two infections of candidal vaginitis in the past 6 months should exercise caution.
    • Individuals with a history of sexually transmitted diseases (STD) or exposure to a partner with STD should consult their healthcare provider.
    • Those with irregular or abnormal bleeding, vaginal ulcers, diarrhea, dysuria or lower abdominal pain, or fever and chills should be closely monitored.
    • The medication is not indicated for systemic fungal infections (oral).
    • Caution is advised for patients with hepatic impairment.
    • Extra care is necessary when administering the medication to children.
    • Special considerations are required during pregnancy and lactation.
  • Drug Interactions

    Drug interactions with clotrimazole include:

    • CYP3A4 substrates (e.g., statins, certain benzodiazepines) (may increase the levels of these drugs by inhibiting CYP3A4)
    • CYP3A4 inducers (e.g., rifampin) (may decrease clotrimazole levels and effectiveness)
    • Warfarin (may increase the risk of bleeding- monitor INR closely)
    • Oral contraceptives (no significant interaction but use additional contraception as a precaution)
    • Antacids (e.g., magnesium or aluminum hydroxide) (may decrease the absorption of clotrimazole- take separately if using clotrimazole orally)
    • Other antifungal agents (e.g., ketoconazole) (may have additive effects or altered efficacy)
    • Immunosuppressants (e.g., cyclosporine) (may increase the risk of systemic side effects)
    • Digoxin (may increase digoxin levels and risk of toxicity)
  • Food Interactions

    As of now, there are no known interactions between this drug and food. However, since comprehensive studies on food interactions may not be available, it is always a good idea to follow general dietary guidelines and consult your healthcare provider or pharmacist if you have any specific concerns or question.

  • Storage/Disposal

    Clotrimazole 1%, a topical antifungal medication, is commonly used to treat skin infections such as athlete's foot, jock itch, and ringworm. To ensure the effectiveness and safety of this medication, proper storage is essential. The medication should be kept in its original container, which is designed to protect it from light and moisture. This container helps maintain the quality and potency of the medication. Storage should occur at room temperature, within the range of 68°F to 77°F (20°C to 25°C). Avoiding humid locations like bathrooms or kitchens is important, as these areas can cause the medication to degrade quickly and become less effective. Additionally, it should be kept away from heat and light sources, including direct sunlight and radiators, as these can also break down the active ingredients and render the medication ineffective. Due to the potential for accidental ingestion or misuse, it is crucial to keep Clotrimazole 1% out of reach of children and store it in a secure location. Ensuring proper storage according to these guidelines will help ensure that the medication remains effective and safe for use when needed. Checking the expiration date and discarding expired medication is recommended. If storage instructions present questions or concerns, consulting a medical professional, such as a doctor or pharmacist, for further guidance is advised.

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