Canesten 1 (0.5g) 1 Vaginal Tablet

Clotrimazole 500mg Tablet primarily works by inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes. It selectively binds to a specific enzyme called lanosterol 14-alpha-demethylase, which is responsible for converting lanosterol to ergosterol in fungi. This binding disrupts the fungal cell membrane structure and function, leading to impaired membrane permeability and the leakage of essential intracellular components. As a result, the growth and replication of susceptible fungi are effectively halted, allowing for the treatment of fungal infections.

Clotrimazole 500mg

Antifungal

Tablet

The following are the uses of Clotrimazole 500mg Tablet:

• Used for treating vaginal yeast infections, providing relief from itching, irritation, and vaginal discharge.
• Used for managing athlete's foot, jock itch, and ringworm, effectively reducing fungal growth on the skin.
• Used for addressing fungal infections in the mouth (oral thrush) by inhibiting the growth of Candida fungi.
• Used for preventing and controlling fungal infections in various parts of the body, including the skin, nails, and scalp.
• Used for managing skin conditions like psoriasis and seborrheic dermatitis when fungal infections are present.
• Used for maintaining intimate hygiene and comfort by eliminating yeast infections in the genital area.
• Used for supporting overall skin and nail health by combating fungal infections that can cause discomfort and discoloration.

In the case of an overdose of Clotrimazole 500mg Tablets, it is important to recognize the potential severity of this situation. Prompt action is necessary, as an excessive amount of the medication can lead to adverse effects. Symptoms may include nausea, vomiting, and in severe cases, liver or kidney problems. If an overdose is suspected, seek medical advice immediately. Time is of the essence, and a healthcare professional should be consulted to provide the necessary guidance and treatment to mitigate any potential harm.

In the case of a missed dose of Clotrimazole 500mg Tablet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen. It is important to adhere to the prescribed dosage and consult a healthcare professional if you have any concerns about missed doses.

To take Clotrimazole 500mg Tablet, place the tablet in your mouth and swallow it with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.

Clotrimazole 500mg Tablet should not be used in the following conditions:

• Do not use if you are allergic to Clotrimazole or other similar antifungal medications.
• Avoid using if you have a history of liver problems or if you are currently experiencing liver issues.
• Not suitable for individuals with a known sensitivity or reaction to any of the tablet's components.
• Contraindicated in patients with rare hereditary problems of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.
• Should not be used if you are pregnant or breastfeeding without medical advice.

The side effects of Clotrimazole 500mg Tablet may include:

• Skin irritation or redness at the application site
• Mild burning or stinging sensation
• Itching or rash
• Peeling or dry skin
• Allergic reactions (skin redness, swelling, or hives)
• Blistering or oozing skin
• Difficulty breathing (in rare cases)
• Increased sensitivity to sunlight

Following are the precautions and warnings for Clotrimazole 500mg Tablet:

• Not suitable for individuals with a known allergy or hypersensitivity to Clotrimazole or other azole antifungals.
• Long-term or repeated use of this medication should be avoided without medical supervision, as it may lead to fungal or bacterial resistance.
• Patients with liver or kidney disease should use this medication with caution and under medical supervision.
• Elderly patients may be more susceptible to the side effects of this medication, and regular monitoring is advised.
• Pregnant and breastfeeding women should consult a healthcare professional before using this medication, as it may pose risks to the fetus or infant.
• This medication is not recommended for children, especially those under 2 years of age, without medical advice.
• If symptoms persist, worsen, or new symptoms appear, seek medical attention immediately and discontinue use.
• Keep out of reach of children and pets.

Following are the drug interactions for Clotrimazole 500mg Tablet:

• Avoid concurrent use with other azole antifungals, as it may increase the risk of adverse effects and toxicity.
• Clotrimazole can increase the effects of oral hypoglycemic agents, leading to low blood sugar levels. Monitor blood glucose levels closely.
• The tablet form may decrease the absorption of H2-blockers, proton pump inhibitors, and certain antimalarial drugs, requiring dosage adjustments.
• Rifampicin, a potent enzyme inducer, can reduce the effectiveness of clotrimazole. Consider alternative antifungal therapy.
• Theophylline levels may be increased when used with clotrimazole, potentially requiring dosage adjustments.
• Warfarin and other anticoagulants may have their effects potentiated, increasing the risk of bleeding. Regular monitoring of INR is advised.
• Certain anti-HIV protease inhibitors may increase clotrimazole levels, requiring close monitoring for adverse effects.

Following are the food interactions for Clotrimazole 500mg Tablet:

• Avoid consuming large amounts of caffeine-rich foods like coffee, tea, and chocolate, as Clotrimazole can potentially increase caffeine levels in the body, leading to heightened caffeine-related side effects.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit the metabolism of Clotrimazole, leading to increased drug levels in the body and potentially enhancing side effects.
• Alcohol consumption should be minimized as it may increase the risk of liver problems, especially with long-term use of Clotrimazole.
• Avoid high-fat meals as they can potentially slow down the absorption of Clotrimazole, affecting its effectiveness.
• Garlic, when taken in large amounts, may interact with Clotrimazole and affect its metabolism, potentially altering its effectiveness.
• Some dairy products like milk and yogurt may decrease the absorption of Clotrimazole, so it's best to separate these by a few hours.
• Avoid natural licorice as it may increase the risk of side effects due to potential interactions with Clotrimazole.
• Consult a doctor if you have a diet rich in cruciferous vegetables like broccoli, cabbage, and kale, as these can potentially affect the metabolism of Clotrimazole.

Clotrimazole 500mg Tablets should be stored in a cool and dry place, preferably at room temperature (around 25°C), away from direct exposure to sunlight, heat, and moisture. The tablets should be kept in their original packaging or container, tightly sealed, to maintain their integrity and effectiveness. It is crucial to ensure that the medication is stored away from children and pets to prevent accidental ingestion. When disposing of unused or expired tablets, it is recommended to follow local guidelines or consult a pharmacist. Do not dispose of them in regular household trash or flush them down the toilet; instead, seek advice on appropriate disposal methods to minimize environmental impact. Always check the expiration date on the packaging and discard any medication that is past its expiry date.

Following are the quick tips for Clotrimazole 500mg Tablet:

• Consult your doctor for the right dosage and duration tailored to your condition.
• Take the tablet with or after meals to minimize stomach-related side effects.
• Ensure you complete the full course of treatment, even if symptoms improve.
• Do not stop the medication early without consulting your doctor.
• Avoid alcohol consumption as it may increase the risk of liver-related side effects.
• Inform your doctor about all medications you are taking to prevent potential drug interactions.
• Store the tablets at room temperature, away from moisture and direct sunlight.
• Keep the medication out of reach of children and pets.