Capril (12.5mg) 30 Tablets

Captopril, a 12.5mg dose in tablet form, acts as a potent angiotensin-converting enzyme (ACE) inhibitor. It primarily blocks the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, thereby reducing blood pressure. By inhibiting ACE, captopril decreases the production of angiotensin II, leading to vasodilation, reduced vascular resistance, and decreased blood pressure. This mechanism allows for improved blood flow, reduced strain on the heart, and better cardiovascular function, making it effective in treating hypertension and certain heart conditions.

Captopril 12.5mg

Angiotensin-converting enzyme (ACE) inhibitor.

Tablet

The following are the uses of Captopril 12.5mg Tablet:

• Used for treating high blood pressure, helping to lower and control blood pressure.
• Used for managing heart failure, improving symptoms and reducing hospital visits.
• Used to enhance survival rates after a heart attack, aiding in recovery.
• Used in diabetic kidney disease, slowing its progression and protecting kidney function.
• Used to alleviate chest pain (angina) by improving blood flow to the heart.
• Used to reduce the risk of cardiovascular events like heart attacks and strokes.
• Used to treat certain kidney disorders, improving kidney function.

In the case of an overdose of Captopril 12.5mg Tablets, symptoms may include a severe drop in blood pressure, leading to lightheadedness or fainting. Other signs can include a rapid or slow heartbeat, confusion, and decreased urination. Immediate action should be taken by contacting a healthcare professional or poison control center for guidance. Prompt medical intervention is necessary to manage symptoms and prevent potential complications from the overdose.

In the case of a missed dose of Captopril 12.5mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for advice on how to safely adjust your medication regimen. It is generally recommended to take the medication as soon as possible after realizing the missed dose.

To take Captopril 12.5mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.

Following are the conditions when Captopril 12.5mg Tablet should not be used:

• Should not be used in patients with a known allergy to Captopril or other angiotensin-converting enzyme (ACE) inhibitors.
• Contraindicated in individuals with a history of angioedema related to previous ACE inhibitor therapy.
• Not recommended for patients with severe renal impairment or renal artery stenosis.
• Should not be used during pregnancy, especially in the second and third trimesters.
• Contraindicated in patients with a history of hereditary or idiopathic angioedema.
• Not suitable for individuals with a history of neutropenia/agranulocytosis or bone marrow depression.

The side effects of Captopril 12.5mg Tablet may include:

• Dizziness or lightheadedness
• Dry cough
• Fatigue or weakness
• Nausea and vomiting
• Diarrhea
• Skin rashes or itching
• Taste disturbances
• Low blood pressure

Following are the precautions and warnings for Captopril 12.5mg Tablet:

• Do not start or continue Captopril if you have a history of angioedema or are allergic to any of its ingredients.
• Close monitoring of kidney function is necessary, especially in patients with existing kidney disease or those on long-term treatment.
• Blood pressure should be regularly monitored, and dosage adjustments should be made if hypotension (low blood pressure) occurs.
• Caution is advised for patients with impaired liver function, as the dosage may need to be adjusted.
• Elderly patients may be more susceptible to the effects of Captopril, particularly dizziness and lightheadedness.
• Patients should be advised to rise slowly from a sitting or lying position to prevent orthostatic hypotension.
• Captopril may cause hyperkalemia (high potassium levels); regular monitoring of potassium levels is recommended.

Following are the drug interactions for Captopril 12.5mg Tablet:

• Lithium and potassium-sparing diuretics (e.g., spironolactone, triamterene) can increase the risk of hyperkalemia when used with Captopril.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce the blood pressure-lowering effect of Captopril and increase the risk of kidney damage.
• The combination of Captopril with other angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) can lead to severe hypotension.
• When used with diuretics, especially loop diuretics, Captopril may cause excessive blood pressure drop and impaired kidney function.
• Captopril can increase the effects of hypoglycemic agents, including insulin, and may lead to low blood sugar levels.
• Nitrates and other antihypertensive medications may have additive effects on blood pressure, requiring close monitoring.
• The risk of neutropenia and agranulocytosis may increase when Captopril is combined with immunosuppressants or drugs known to cause bone marrow suppression.

Following are the food interactions for Captopril 12.5mg Tablet:

• Avoid excessive salt (sodium) intake in your diet, as Captopril may cause sodium and water retention, leading to increased blood pressure.
• Limit the consumption of potassium-rich foods like bananas, oranges, and tomatoes, as Captopril can increase potassium levels in the body.
• Alcohol may increase the risk of dizziness and drowsiness when combined with Captopril, so it's best to avoid or limit alcohol consumption.
• Grapefruit and grapefruit juice should be avoided, as they can increase the levels of Captopril in the blood, potentially leading to an increased risk of side effects.
• Maintain a balanced diet and monitor your fluid intake, as Captopril can sometimes cause dehydration.
• Avoid high-fat meals, as they may decrease the absorption of Captopril, reducing its effectiveness.
• Consult your healthcare provider for personalized dietary advice, especially if you have kidney or liver issues, as these organs play a role in Captopril's metabolism.

Captopril 12.5mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet, at room temperature, avoiding exposure to direct sunlight, heat, or moisture. It is crucial to keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent degradation. Always check the expiration date before taking any medication, and never use tablets beyond their expiry. For disposal, do not flush or pour the medication down the drain; instead, consult your pharmacist or local waste management guidelines for safe disposal practices. Keep the medication away from children and pets to prevent accidental ingestion, and ensure the container is child-resistant.

Following are the quick tips for Captopril 12.5mg Tablet:

• Start with a low dose and gradually increase as directed by your doctor.
• Take the tablet on an empty stomach, preferably 1 hour before meals.
• Avoid consuming salt substitutes or potassium supplements without medical advice.
• Monitor blood pressure regularly while on this medication.
• Inform your doctor about all medications you are taking to avoid interactions.
• Store the tablets in a cool, dry place, away from direct sunlight.
• Do not stop taking the medication without consulting your doctor.