Capril (25mg) 30 Tablets

Captopril, a 25mg tablet, acts as an angiotensin-converting enzyme (ACE) inhibitor. It primarily blocks the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, by inhibiting the ACE enzyme. This inhibition leads to decreased angiotensin II levels, resulting in reduced vasoconstriction and lowered blood pressure. Additionally, captopril promotes the release of vasodilatory kinins, further contributing to its blood pressure-lowering effect. By inhibiting ACE and its downstream effects, captopril effectively reduces systemic vascular resistance, lowers blood pressure, and improves cardiovascular function.

Captopril 25mg

Angiotensin-converting enzyme (ACE) inhibitor.

Tablet

The following are the uses of Captopril 25mg Tablet:

• Used for treating high blood pressure, helping to prevent heart attacks and strokes.
• Used to improve survival rates after a heart attack, ensuring the heart functions effectively.
• Used in heart failure cases to reduce the risk of hospitalization and improve symptoms.
• Used to treat kidney disease associated with diabetes, protecting kidney function.
• Used to manage certain types of chronic headaches, reducing their frequency and severity.
• Used pre-surgery to lower blood pressure and protect the heart in high-risk patients.
• Used to treat rare conditions like Marfan syndrome and RPGN, slowing disease progression.

In the case of an overdose of Captopril 25mg Tablets, it is important to recognize the potential severity of the situation. An overdose may lead to symptoms such as a rapid drop in blood pressure, dizziness, and fainting. If an overdose is suspected, it is crucial to seek medical advice promptly. Contact a healthcare professional or emergency services for guidance on the appropriate steps to take, as they can provide specific instructions for managing the overdose and ensure the necessary medical care is administered.

In the case of a missed dose of Captopril 25mg Tablet, it is generally advised to take the missed dose as soon as you remember. However, if it's almost time for your next scheduled dose, it's best to skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one. If you frequently miss doses, it's important to consult your healthcare provider for guidance, as they may recommend adjusting your dosing schedule or provide specific instructions for managing missed doses.

To take Captopril 25mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.

Here are the conditions and situations when Captopril 25mg Tablet should not be used:

• Must not be used in patients with a known allergy or hypersensitivity to Captopril or any other angiotensin-converting enzyme (ACE) inhibitors.
• Contraindicated in patients with a history of angioedema, whether it was associated with previous ACE inhibitor therapy or not.
• Should not be used during pregnancy, especially during the second and third trimesters, as it can cause potential fetal harm.
• Not recommended for individuals with severe renal impairment or patients undergoing dialysis.
• Contraindicated in patients with bilateral renal artery stenosis.
• Should be avoided in patients with a history of hereditary or idiopathic angioedema.
• Not suitable for individuals with a history of neutropenia/agranulocytosis or bone marrow depression.

The side effects of Captopril 25mg Tablet may include:

• Dizziness
• Fatigue or weakness
• Dry cough
• Headache
• Nausea and vomiting
• Diarrhea
• Skin rash or itching
• Loss of taste

Following are the precautions and warnings for Captopril 25mg Tablet:

• Patients with a known allergy to Captopril or any other ACE inhibitors should not take this medication.
• Regular monitoring of kidney function is necessary, especially in patients with pre-existing kidney disease, as Captopril can affect renal function.
• Blood pressure should be monitored closely, particularly in patients with hypertension, as Captopril can cause hypotension.
• Patients with a history of angioedema should exercise caution, as Captopril may increase the risk of this condition.
• This medication may cause dizziness; patients should avoid activities requiring mental alertness until they know how it affects them.
• Captopril may cause hyperkalemia, so regular monitoring of potassium levels is advised, especially in patients with renal impairment.
• Pregnant and breastfeeding women should consult their doctor before taking Captopril, as it may have adverse effects on the fetus and infant.
• Diabetic patients should be cautious as Captopril may increase blood sugar levels.

Following are the drug interactions for Captopril 25mg Tablet:

• Lithium and potassium-sparing diuretics (e.g., spironolactone) may increase the risk of hyperkalemia when used with Captopril.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce the blood pressure-lowering effect of Captopril and may increase the risk of kidney problems.
• When combined with nitrates, Captopril may cause a significant drop in blood pressure, potentially leading to hypotension.
• The risk of angioedema is increased when Captopril is used with drugs that inhibit the enzyme dipeptidyl peptidase-4 (DPP-4) inhibitors, such as vildagliptin.
• Antidiabetic medications may require dosage adjustments when used with Captopril, as it may increase blood glucose levels.
• Immunosuppressants like cyclosporine may have their blood levels affected by Captopril, requiring close monitoring.
• Concurrent use of trimethoprim, a type of antibiotic, can increase the risk of hyperkalemia and decrease the effectiveness of Captopril.

Following are the food interactions for Captopril 25mg Tablet:

• Potassium-rich foods like bananas, oranges, and spinach should be consumed in moderation as Captopril can increase potassium levels in the body, potentially leading to hyperkalemia.
• Salt substitutes or low-sodium milk products containing potassium should be used with caution as they may also contribute to elevated potassium levels.
• Alcohol consumption should be minimized or avoided as it can further lower blood pressure, especially when combined with Captopril, which may cause excessive drops in blood pressure.
• Grapefruit and grapefruit juice are best avoided as they can increase the levels of Captopril in the blood, potentially leading to an increased risk of side effects.
• Maintain a balanced diet, as Captopril may cause a loss of taste, making it important to ensure you're getting all the necessary nutrients.
• Stay well-hydrated, especially if you experience diarrhea or vomiting, to prevent dehydration.
• Consult a healthcare professional for personalized advice on diet and medication interactions.

Captopril 25mg Tablets should be stored in a cool and dry place, preferably at room temperature (around 25°C/77°F). Protect the tablets from excessive heat, moisture, and direct sunlight, as these conditions can degrade the medication. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to air and humidity. It is crucial to dispose of any unused or expired tablets properly; do not throw them into the trash or flush them down the toilet. Contact your pharmacist or healthcare provider for guidance on safe disposal methods. Remember to keep all medications out of children's reach to ensure their safety.

Following are the quick tips for Captopril 25mg Tablet:

• Consult your doctor before starting this medication and provide a complete medical history.
• Take the tablet as directed by your doctor, typically 2-3 times a day.
• Take the tablet on an empty stomach, preferably 1 hour before meals.
• Maintain a consistent daily routine for better effectiveness.
• Avoid strenuous exercise and hot showers/baths as they may cause dizziness.
• Do not drive or operate machinery if you feel dizzy or lightheaded.
• Regularly monitor your blood pressure and kidney function while on this medication.