Carbex Plus (100/2.5mg) 120ml Syrup

Carbocisteine and Promethazine Hydrochloride work synergistically in the syrup/suspension form. Carbocisteine, a mucolytic agent, reduces the viscosity of mucus by breaking down disulfide bonds in mucin, thereby improving its clearance from the respiratory tract. Promethazine Hydrochloride, an antihistamine, blocks histamine receptors, which reduces the production of mucus and suppresses the cough reflex. Together, they help to thin and loosen mucus, making it easier to expel, and provide relief from cough and congestion.

Carbocisteine, Promethazine Hydrochloride 2.5mg

Expectorant, Antihistamine.

Suspension

The following are the uses of Carbocisteine, Promethazine Hydrochloride 2.5mg Syrup/Suspension:

• Used for relieving dry coughs and soothing irritated throats.
• Used for reducing inflammation in the airways and loosening mucus.
• Used for managing symptoms of allergic reactions and hay fever.
• Used for reducing nausea and vomiting associated with various conditions.
• Used for suppressing coughs and aiding better sleep in patients.
• Used for easing symptoms of upper respiratory tract infections.
• Used for pre-operative medication to reduce anxiety and prevent nausea.

In the case of an overdose of Carbocisteine, prompt medical attention is required. Symptoms may include nausea, vomiting, and gastrointestinal discomfort. For Promethazine Hydrochloride 2.5mg Syrup/Suspension overdose, effects can range from drowsiness and confusion to more severe reactions like respiratory depression, especially in children. Immediate medical intervention is necessary to manage these potential consequences.

In the case of a missed dose of Carbocisteine, administer the medication as soon as possible, but if it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. For Promethazine Hydrochloride 2.5mg Syrup/Suspension, if a dose is missed, take it as soon as you remember, but if it's close to the time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose to make up for a missed one.

To administer Carbocisteine and Promethazine Hydrochloride 2.5mg Syrup/Suspension, shake the bottle thoroughly, measure the prescribed dose with an accurate measuring device, and take it orally as directed by your healthcare provider, typically once or twice a day, with or without food, following the recommended dosage guidelines for your age and condition.

Following are the conditions when Carbocisteine, Promethazine Hydrochloride 2.5mg Syrup/Suspension should not be used:

• Must not be administered to individuals with a known allergy to Carbocisteine, Promethazine Hydrochloride, or any other ingredients in the medication.
• Contraindicated in patients with respiratory depression or severe breathing disorders.
• Should not be given to children under 2 years of age due to potential risks.
• Not recommended for individuals with a history of seizures or epilepsy.
• Avoid using in patients with narrow-angle glaucoma or increased intraocular pressure.
• Contraindicated during the last trimester of pregnancy.
• Do not use in patients with a history of liver or kidney disease.

The side effects of Carbocisteine and Promethazine Hydrochloride 2.5mg Syrup/Suspension may include:

• Nausea and vomiting
• Drowsiness or sedation
• Dry mouth
• Blurred vision
• Constipation
• Allergic reactions (such as rash, itching)
• Difficulty in breathing or respiratory depression (rare)
• Confusion or disorientation (especially in elderly patients)

Here are the precautions and warnings for Carbocisteine, Promethazine Hydrochloride 2.5mg Syrup/Suspension:

• Avoid use if you are allergic to Carbocisteine, Promethazine, or any other ingredients in the medication.
• Use with caution in patients with kidney or liver problems as it may require dosage adjustments.
• This medication may cause drowsiness or dizziness, so avoid driving or operating heavy machinery until you know how it affects you.
• Do not consume alcohol while taking this medication as it can increase the risk of side effects.
• Consult your doctor if you have a history of respiratory problems, asthma, or if you are taking other medications, especially those affecting the central nervous system.
• Promethazine may cause photosensitivity, so limit sun exposure and use protective measures when outdoors.
• Not recommended for use in children under 2 years of age unless prescribed by a healthcare professional.
• Pregnant and breastfeeding women should consult their doctor before taking this medication as it may have potential risks to the fetus or infant.

Following are the drug interactions for Carbocisteine, Promethazine Hydrochloride 2.5mg Syrup/Suspension:

• Antihistamines and other CNS depressants may enhance sedative effects, including opioids, benzodiazepines, and alcohol, potentially leading to increased drowsiness and impaired coordination.
• Carbocisteine may reduce the absorption of tetracycline antibiotics, so separate administration by at least 2 hours.
• Concomitant use with other cough suppressants or expectorants may lead to excessive mucus thinning or suppression of the cough reflex.
• Promethazine can lower the seizure threshold, so caution is needed when combined with anticonvulsant medications.
• Monoamine oxidase inhibitors (MAOIs) should be avoided due to the risk of serotonin syndrome.
• Anticholinergic drugs may have additive side effects when used with promethazine, such as dry mouth, blurred vision, and urinary retention.
• Drugs that prolong the QT interval, such as certain antiarrhythmics or antipsychotics, may increase the risk of cardiac arrhythmias when combined with promethazine.

Following are the food interactions for Carbocisteine, Promethazine Hydrochloride 2.5mg Syrup/Suspension:

• Alcohol consumption should be avoided as it can increase the sedative effects of Promethazine Hydrochloride, leading to enhanced drowsiness and reduced alertness.
• Grapefruit and grapefruit juice should be consumed with caution as they may interfere with the metabolism of Carbocisteine, potentially increasing its blood levels and associated side effects.
• Dairy products like milk and cheese can reduce the absorption of Carbocisteine, so it is advisable to separate their consumption by a few hours.
• Foods high in sugar content may interact with the syrup/suspension's flavor and effectiveness, potentially increasing the risk of tooth decay.
• Avoid spicy foods as they can irritate the throat, especially when combined with the syrup/suspension.
• Consuming high-fat meals might delay the absorption of Carbocisteine, affecting its effectiveness.
• Certain acidic foods like citrus fruits and tomatoes may cause throat irritation, especially when taken along with the medication.
• It is generally recommended to maintain a balanced diet to support overall health during the medication period.

Carbocisteine and Promethazine Hydrochloride 2.5mg Syrup/Suspension should be stored in a cool and dry place, preferably at room temperature, ensuring it is kept away from direct sunlight and moisture. The medication bottle should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to expose the syrup to extreme temperatures, so avoid storing it near heat sources or in the bathroom. When disposing of unused or expired medication, do not flush it or pour it down the drain; instead, seek advice from a pharmacist or healthcare professional on the appropriate disposal methods. Additionally, always keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Carbocisteine and Promethazine Hydrochloride 2.5mg Syrup/Suspension:

• Consult a doctor for dosage instructions based on your medical condition.
• Ensure you understand the dosage and duration prescribed.
• Shake the bottle well before each use to ensure proper mixing.
• Administer the syrup/suspension with a measuring cup or spoon provided.
• Avoid using a household spoon as it may not provide accurate dosing.
• Store the medication at room temperature, away from moisture and direct sunlight.
• Keep a record of your medication schedule to ensure you don't miss a dose.