Cardaxen (50mg) 20 Tablets

Atenolol is a synthetic, beta-selective (cardioselective) adrenoreceptor blocking agent, without membrane stabilizing or intrinsic sympathomimetic (partial agonist) activities.This drug works by blocking the action of certain natural chemicals like epinephrine in your body, on the heart and blood vessels. This mechanism lowers the heart rate, blood pressure, and strain on the heart. Atenolol is indicated in the management of hemodynamically stable patients with definite or suspected acute myocardial infarction to reduce cardiovascular mortality. Treatment can be initiated as soon as the patient's clinical condition allows.

Atenolol

Tablet

Hypertension Totamol is indicated in the management of hypertension, angina Pectoris due to Coronary atherosclerosis, long-term management of patients with angina pectoris, acute myocardial infarction.

Dose must be taken according to doctor’s advice only; doses given below are suggested as supportive literature for better understanding in some areas of requirements. Tablets of strength; 25mg, 50mg and 100mg are available, should be used according to doctor’s advice. Adult dose: For angina: Initial dose is 50mg orally once a day, increase to 100mg orally once a day after 1 week if optimal response is not achieved. Maintenance dose is 50 to 200mg orally once a day, maximum dose is 200mg per day. For angina pectoris: Initial dose is 50mg orally once a day, Increase to 100mg orally once a day after 1 week if optimal response is not achieved. Maintenance dose is 50 to 200 mg orally once a day, maximum dose is 200mg per day. For Myocardial Infarction: Dose must be 50mg orally twice a day or 100 mg orally once a day. For hypertension in old age people: Try to reduce the starting dose to 25mg orally once a day.

Contact your doctor for management of overdose. Intoxication occurs, excessive bradycardia may be counteracted by Atropine (1-2 mg IV) followed by, if necessary, a beta- stimulant such as Isoprenaline.

In case you missed any dose, take the next dose as soon as you remember, but don't double your next dose to compensate for the missed one.

Used alone or concomitantly with other antihypertensive agents, particularly with a thiazide- type diuretic.

Treatment with Atenolol , as with other beta-blockers, is contraindicated in patients with the following: Known hypersensitivity to the drug, heart block (second or third degree), bradycardia, cardiogenic shock, severe peripheral arterial circulatory disturbances and sick sinus syndrome.

Cold extremities Muscular fatigue Bradycardia Dizziness Dry mouth Sleep disturbances Respiratory bronchospasm (may occur in patients with bronchial asthma)

In case of reduction of the heart rate to 45 beats/minute or below, dose should be reduced or medication withdrawn. Dosage should be adjusted in patients with impaired renal function. May mask the signs of thyrotoxicosis. Administration of Atenolol during pregnancy should be avoided, unless the benefits outweigh the possible risks as it can cross the placenta. There is significant accumulation of Atenolol in breast milk.

Foods rich in sodium content may reduce the blood pressure-lowering effect of Atenolol .

Store below 25°C in a dry place. Protect from light.