Carlov (6.25mg) 30 Tablets

Carvedilol, the active ingredient in Carvedilol 6.25mg Tablet, acts as a non-selective beta-blocker and alpha-1 adrenergic receptor antagonist. Its mechanism of action involves blocking both beta-1 and beta-2 adrenergic receptors in the heart and vascular smooth muscle. By blocking beta-1 receptors, carvedilol reduces heart rate and cardiac output, leading to decreased blood pressure. Simultaneously, its blockade of beta-2 receptors in the vascular smooth muscle results in vasodilation, further contributing to blood pressure reduction. Additionally, carvedilol's alpha-1 receptor antagonism causes direct vasodilation, particularly in the peripheral arteries, which helps to lower peripheral vascular resistance and improve blood flow. This combined mechanism of action makes carvedilol effective in treating hypertension and certain cardiovascular conditions by reducing cardiac workload and improving overall cardiovascular function.

Carvedilol 6.25mg

Beta-blocker.

Tablet

The following are the uses of Carvedilol 6.25mg Tablet:

• Used for treating high blood pressure, helping to lower and control blood pressure levels.
• Used for managing angina, reducing the frequency and severity of chest pain episodes.
• Used to improve survival rates after a heart attack, supporting heart function and recovery.
• Used in the treatment of heart failure, enhancing heart muscle function and managing symptoms.
• Used to reduce the risk of sudden death in patients with severe heart issues, providing vital support.
• Used to manage irregular heart rhythms, helping to regulate the heartbeat.
• Used to protect the heart in conditions like cardiomyopathy, preventing further damage.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• High Blood Pressure (Hypertension) - Initial dose is usually 6.25mg once or twice daily, Maintenance dose ranges from 25mg to 50mg once daily or 12.5mg to 25mg in divided doses, Doses up to 100mg daily are recommended for higher blood pressure values or in combination therapy
• Heart Failure - Initial dose is usually 6.25mg twice a day, Target dose is 25mg twice daily, but can be increased to 50mg twice daily if needed and depending on the clinical situation
• Angina (Chest Pain Due to Coronary Artery Disease) - Initial dose is usually 6.25mg twice a day, Target dose is 25mg twice daily, can be increased to 50mg twice daily if necessary

In the case of an overdose of Carvedilol 6.25mg Tablets, symptoms may include dizziness, fatigue, low blood pressure, and a slow heart rate. If you suspect an overdose, seek medical advice immediately. Promptly contact a healthcare professional or go to the nearest emergency department. Treatment may involve supportive measures such as monitoring vital signs and managing symptoms until the medication is cleared from the system. It is crucial to act swiftly to ensure the best possible outcome.

In the case of a missed dose of Carvedilol 6.25mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Avoid taking extra medicine to make up for a missed dose, as this may increase the risk of side effects. It is advisable to consult your healthcare professional for specific instructions if you frequently miss doses or are unsure about how to manage missed doses.

To take Carvedilol 6.25mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare provider.

Following are the conditions when Carvedilol 6.25mg Tablet should not be used:

• Should not be taken by patients with a known allergy to Carvedilol or any other beta-blockers.
• Not suitable for individuals with severe liver disease or reduced liver function.
• Contraindicated in patients with severe heart failure that requires inotropic therapy.
• Should not be used in patients with a history of slow heart rate (bradycardia).
• Avoid using if you have a history of severe asthma or chronic obstructive pulmonary disease (COPD).
• Not recommended for individuals with a history of severe peripheral vascular disease.
• Do not take this medication if you have a history of cardiogenic shock.

The side effects of Carvedilol 6.25mg Tablet may include:

• Dizziness or lightheadedness
• Fatigue or weakness
• Headache
• Nausea or vomiting
• Diarrhea or constipation
• Dry mouth
• Difficulty sleeping (insomnia)
• Skin rashes or itching

Following are the precautions and warnings for Carvedilol 6.25mg Tablet:

• Do not abruptly discontinue the medication; gradual reduction is advised to minimize the risk of exacerbation of angina pectoris, myocardial infarction, or ventricular arrhythmias.
• Patients with a history of severe anaphylactic reactions to allergens may not respond to the usual doses of epinephrine, so alternative treatments should be considered.
• Carvedilol can mask the symptoms of hypoglycemia, especially tachycardia, so monitor blood glucose levels closely in diabetic patients.
• Use with caution in patients with severe hepatic impairment; consider starting with a lower dose and monitor closely.
• May cause bradycardia and worsen heart failure; monitor heart rate and adjust dosage accordingly.
• Not recommended in patients with severe bronchospastic disease due to its beta-blocking properties.
• May cause or exacerbate peripheral arterial circulatory disorders, especially in patients with pre-existing conditions.
• Regularly monitor blood pressure, heart rate, and renal function during treatment, particularly in patients with renal impairment.

Following are the drug interactions for Carvedilol 6.25mg Tablet:

• Concomitant use with other beta-blockers can increase the risk of bradycardia and hypotension.
• It may interact with calcium channel blockers, leading to enhanced hypotensive effects.
• Carvedilol can increase the levels of digoxin, requiring close monitoring of digoxin levels.
• The effect of insulin and oral hypoglycemic agents may be enhanced, increasing the risk of hypoglycemia.
• Caution is advised with nonsteroidal anti-inflammatory drugs (NSAIDs) as they may reduce the antihypertensive effects of Carvedilol.
• Rifampin can decrease the levels of Carvedilol, potentially reducing its effectiveness.
• The use of Class I antiarrhythmic agents with Carvedilol may increase the risk of AV block and severe bradycardia.

Following are the food interactions for Carvedilol 6.25mg Tablet:

• Alcohol consumption should be minimized or avoided as it may increase the risk of dizziness and lightheadedness, especially when starting the medication.
• Grapefruit and grapefruit juice should be avoided as they can interfere with the metabolism of Carvedilol, leading to increased drug levels in the body and potential side effects.
• Salt substitutes containing potassium should be used cautiously as Carvedilol may increase potassium levels in the blood.
• High-fiber foods like whole grains, legumes, and vegetables can be beneficial as they may help control cholesterol and blood sugar levels, which is important when taking Carvedilol for blood pressure management.
• Limit the intake of foods high in tyramine, such as aged cheeses, cured meats, and certain types of beer, as Carvedilol may interact with tyramine and cause a sudden increase in blood pressure.
• Caffeinated beverages like coffee, tea, and energy drinks may reduce the effectiveness of Carvedilol, so it's advisable to moderate their consumption.
• A balanced diet low in saturated fats and trans fats is recommended to support overall cardiovascular health while taking Carvedilol.
• It is generally safe to consume with most foods, but always follow your healthcare provider's dietary recommendations.

Carvedilol 6.25mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. It is crucial to avoid exposing the medication to extreme temperatures, so steer clear of storing it in the bathroom or near heat sources. Regularly check the expiration date, and if the tablets are past their prime or no longer needed, do not flush them or throw them into the garbage. Contact your pharmacist or healthcare provider for guidance on safe disposal methods to minimize environmental impact. Keep this medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Carvedilol 6.25mg Tablet:

• Take the tablet as directed by your doctor, usually twice a day.
• Consume the tablet at the same time each day to maintain a consistent level in your body.
• Carvedilol can be taken with or without food, but taking it with food may reduce the risk of stomach upset.
• Ensure you swallow the tablet whole without crushing or chewing for optimal absorption.
• Do not suddenly stop taking this medication without consulting your doctor to prevent potential complications.
• Regularly monitor your blood pressure and heart rate as advised by your healthcare provider.
• Store the medication at room temperature, away from moisture and light.

When taking Carvedilol 6.25mg, it is not usual to require lab tests for prescription validation. Nevertheless, it is vital to periodically monitor specific health parameters to ensure the medication's effectiveness and safety. Therefore, based on a person's age, health history, and other factors, a doctor may recommend specific lab tests to monitor certain health parameters while taking Carvedilol. Blood Pressure Monitoring is crucial for individuals taking Carvedilol, especially if they have High Blood Pressure manifestations. This helps to adjust the medication effectively to control blood pressure levels and avoids any potential complications. An Electrocardiogram (ECG) may be recommended by a doctor if you have a history of heart disease or heart-related symptoms. This helps to monitor the heart's electrical activity and detect any arrhythmias or other heart-related issues. Since Carvedilol is excreted through the kidneys, Kidney Function Testing is essential to periodically check kidney function. This helps to ensure that the kidneys adequately remove the drug from the body and monitors for any signs of kidney damage. Although Liver Function Tests are not mandatory, it is helpful to monitor liver enzymes and overall liver health, especially in individuals with a history of liver disease or who are taking other medications that may impact liver function. It is crucial to update your doctor with past and present medical conditions, allergies, and medications (including herbs and supplements) to minimize the risk of drug interactions and ensure the safety of taking Carvedilol 6.25mg.