Carsel 25 (25mg) 30 Tablets

Metoprolol 25mg tablets primarily work by selectively blocking beta-1 adrenergic receptors in the heart. This mechanism of action reduces the heart rate and decreases the force of contraction, leading to a reduction in cardiac output. By blocking these receptors, metoprolol inhibits the binding of catecholamines like adrenaline and noradrenaline, which normally stimulate the heart to beat faster and with more force. As a result, it helps to lower blood pressure and control heart rate, making it useful in the management of hypertension and certain cardiovascular conditions.

Beta-blocker

Tablet

The following are the uses of Metoprolol 25mg Tablet:

• Used for lowering high blood pressure (hypertension) and reducing associated risks
• Used for treating chest pain due to reduced blood flow to the heart (angina)
• Used to improve survival after a heart attack by reducing the risk of further complications
• Used for controlling irregular and rapid heartbeats (arrhythmias)
• Used to prevent migraines in those experiencing frequent episodes
• Used to treat conditions like hyperthyroidism where the thyroid gland produces too much hormone
• Used to reduce symptoms of anxiety, including a rapid heartbeat

In the case of an overdose of Metoprolol 25mg Tablets, it is crucial to recognize the signs and take prompt action. Symptoms may include severe dizziness, extreme fatigue, slow heartbeat, and difficulty breathing. If an overdose is suspected, seek medical advice immediately. Quick response can help prevent serious complications, so ensure you contact a healthcare professional or go to the nearest emergency room for timely treatment and management.

In the case of a missed dose of Metoprolol 25mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication without affecting your treatment plan. It's best to set reminders or keep the medication in a visible place to help you remember to take it as prescribed.

To take Metoprolol 25mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare provider.

Following are the conditions or circumstances when Metoprolol 25mg Tablet should not be taken:

• Metoprolol 25mg Tablet should not be used in patients with a known allergy to beta-blockers or any of its ingredients.
• Avoid using in patients with severe heart-related conditions such as heart block, sick sinus syndrome, or severe heart failure.
• Do not use if the patient has asthma, chronic obstructive pulmonary disease (COPD), or other severe lung problems.
• Contraindicated in patients with a history of slow heart rate (bradycardia) and low blood pressure (hypotension).
• Should not be used during an acute heart attack.
• Not recommended for patients with severe blood circulation problems in the limbs (peripheral vascular disease).
• Avoid using in patients with metabolic acidosis, a condition where the blood has high levels of acid.

The side effects of Metoprolol 25mg Tablet may include:

• Fatigue and weakness
• Dizziness or lightheadedness
• Cold extremities (hands and feet)
• Slow heart rate (bradycardia)
• Shortness of breath
• Nausea and vomiting
• Sleep disturbances
• Diarrhea

Following are the precautions and warnings for Metoprolol 25mg Tablet:

• Do not abruptly stop taking this medication; gradual reduction is advised to prevent adverse effects.
• Patients with heart conditions like heart block, sick sinus syndrome, or severe heart failure should use with caution and regular monitoring.
• This medication may mask the symptoms of low blood sugar in diabetic patients.
• Not recommended for individuals with severe peripheral circulatory disorders, as it may exacerbate symptoms.
• Patients with lung diseases such as asthma or chronic obstructive pulmonary disease (COPD) should use with caution.
• May cause dizziness or lightheadedness; avoid situations where alertness is crucial until the full effects are known.
• Elderly patients may be more sensitive to the effects, requiring careful dose adjustment.

Following are the drug interactions for Metoprolol 25mg Tablet:

• Drugs that may cause bradycardia (slow heart rate) such as other beta-blockers, calcium channel blockers, or certain antiarrhythmic medications can enhance the effect of Metoprolol, leading to excessive bradycardia.
• Concomitant use with clonidine may cause significant cardiovascular adverse effects. Discontinuation of either drug may lead to increased blood pressure.
• Metoprolol can increase the plasma levels of lithium and decrease its renal clearance, potentially resulting in lithium toxicity.
• The antihypertensive effect of Metoprolol may be reduced by NSAIDs (e.g., ibuprofen, naproxen), possibly leading to decreased blood pressure control.
• The use of Metoprolol with verapamil can lead to significant bradycardia and heart block, especially in patients with sinus node dysfunction.
• Rifampicin can reduce the effectiveness of Metoprolol by increasing its metabolism, potentially leading to reduced blood pressure control.
• Metoprolol may increase the plasma concentrations of digoxin, leading to potential digoxin toxicity. Monitoring of digoxin levels is advised.

Following are the food interactions to be aware of when taking Metoprolol 25mg Tablets:

• Grapefruit and grapefruit juice should be avoided as they can increase the concentration of Metoprolol in the blood, potentially leading to an increased risk of side effects.
• Alcohol consumption should be limited as it can reduce the effectiveness of Metoprolol and may cause excessive dizziness or lightheadedness.
• Caffeinated beverages like coffee or energy drinks might counteract the medication's purpose, as they can increase heart rate and blood pressure.
• Avoid high-sodium foods, as Metoprolol may reduce the body's ability to eliminate excess salt, potentially causing fluid retention.
• Consuming large amounts of licorice might reduce the effectiveness of Metoprolol due to its potential to increase blood pressure.
• Be cautious with foods rich in Vitamin K (like spinach, kale, and broccoli) as Metoprolol can alter blood clotting mechanisms.
• Ensure a balanced diet, as Metoprolol may mask some symptoms of low blood sugar, especially in diabetics.
• Always consult your healthcare provider for personalized advice regarding dietary adjustments while on this medication.

Metoprolol 25mg Tablets should be stored in a cool and dry place, preferably at room temperature (68°F to 77°F). Keep the tablets in their original container, tightly sealed, to protect them from moisture and light. It is crucial to ensure that the medication is stored away from children and pets to prevent accidental ingestion. Do not store the tablets in the bathroom or any areas with high humidity as it can affect their quality. Always check the expiration date, and if the tablets are expired or no longer needed, proper disposal is essential. Do not throw them into the trash or flush them down the toilet; instead, consult your pharmacist or healthcare provider for safe disposal instructions to protect the environment.

Following are the quick tips for Metoprolol 25mg Tablet:

• Always take the tablet as directed by your doctor; do not adjust the dosage without medical advice.
• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
• Take the tablet at the same time each day to maintain a consistent level in your body.
• If you experience dizziness, rise slowly from a sitting or lying position to prevent falls.
• Avoid alcohol consumption as it may increase side effects and interact with the medication.
• Do not stop taking the medication suddenly without consulting your doctor.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.