Cef-OD (400mg) 5 Capsules

Cefixime is a third-generation cephalosporin antibiotic, widely used to treat bacterial infections of the respiratory tract, urinary tract, skin, and otitis media (middle ear infections) in children. Its effectiveness arises from its ability to interfere with the synthesis of bacterial cell walls, specifically by binding to a target enzyme called penicillin-binding protein (PBP) located within the cell wall. This binding action inhibits PBP activity, which is essential for cell wall formation and maintenance. Consequently, the bacterial cell wall becomes weaker and less stable, leading to its rupture and the demise of the bacterial cells. It's important to note that cefixime's efficacy is limited to treating bacterial infections and is not effective against viral infections like the common cold or influenza. Additionally, some bacteria have developed resistance to cefixime, particularly those with genetic mutations or exposure to other antibiotics. As a result, it is less effective or wholly ineffective against these resistant strains. When considering a course of cefixime, or any antibiotic, it is always advisable to consult with a healthcare professional, who can advise on appropriate dosage, duration of treatment, and potential side effects.

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Cephalosporin

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Capsule

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Unveiling its multifaceted uses and transformative applications as follows:

• Treatment for bacterial infections in the respiratory tract, gonorrhea, and certain uncomplicated urinary tract infections
• Short course of treatment for pneumonia, including community-acquired pneumonia, acute exacerbations of chronic bronchitis, and acute bacterial sinusitis
• Abdominal infections, jaw and genital infections, and bacteremia
• Pediatric uses including otitis media, pneumonia, urinary tract infections, and sinusitis
• Cefixime is a cephalosporin antibiotic and is considered a first-generation cephalosporin
• Cefixime blocks the synthesis of bacterial cell walls and thus inhibits microbial growth
• Consult your healthcare provider to determine if you need this medication for a bacterial infection
• This information is solely for informational purposes and should not be used for diagnosing any medical condition

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Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

For Adults

• Dosage ranges from 400-800 mg a day
• Maximum dose of 1600 mg per day

For Children

• Dosage recommended is 10 mg/kg of body weight once a day
• Maximum of 400 mg per day

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An overdose of Cefixime is not expected to produce serious symptoms if taken alone, but it may lead to serious complications when mixed with other drugs or alcohol. Therefore, it is crucial to seek immediate medical attention in case of an overdose of Cefixime. The medical team will need as much information as possible about the overdose, any current medications, and any underlying medical conditions to best treat the patient. The treatment may involve using drugs to counter the effects of the overdose, and in some cases, ventilation may be necessary. The medical team will best be able to determine these needs through their professional expertise and treatment options.

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If you have missed a dose of cefixime, it is important to take it as soon as possible. However, if it is almost time for your next scheduled dose, it is recommended to skip the missed dose and continue with your regular schedule. This is to ensure that you don't double the dose accidentally. If you are unsure about how to proceed, it's best to refer to the instructions provided by your doctor or pharmacist, or contact them directly for advice. It is essential to take cefixime as directed and complete the full course of treatment, as prescribed, to ensure the best results and reduce the risk of resistance. If you have any further questions or concerns about missing a dose of cefixime, don't hesitate to consult with your healthcare provider for guidance specific to your situation.

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Before taking Cefixime, it is important to inform your doctor about any medical conditions you may have and any other medications you are currently taking. Cefixime is usually taken every 12 hours or as directed by the physician. It is advisable to take each dose with a full glass of water, with or without food. To achieve the best effect, it is necessary to complete the full course of treatment, even if symptoms improve. Some side effects of this medication may include nausea, loose stools or vomiting, diarrhea, urgent repeated or painful urination, and an allergic reaction such as hives, swelling of the lips, face, throat, or tongue. Serious side effects that require medical attention include difficulty breathing or shortness of breath, changes in vision or eye pain, severe allergic reaction, jaundice (yellowing of the skin or eyes), muscle weakness, pain, or tenderness, and seizures. This is not the complete list of side effects, and others may occur. It is essential to only use this medication according to the prescription and for the prescribed duration. Please consult your physician if you have any questions or concerns regarding your condition or this medication.

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Discerning instances where this medication may not be appropriate:

• You are allergic to cefixime or any other ingredients in the medication. If you have had a severe allergic reaction to penicillin, you could also be allergic to cefixime. It is important to note that allergies can also manifest themselves in a variety of ways including hives, itching, or difficulty in breathing. If this happens after taking cefixime, it is important to seek medical attention.
• You have a history of liver disease or a severe infection. This is because cefixime can cause abnormalities in liver function tests and can increase the risk of liver failure. This is especially the case for those who have a history of liver disease or a compromised immune system.
• You are pregnant or breastfeeding. This is because there are no well-controlled studies that demonstrate the safety of cefixime in pregnant women and infants. Although cefixime has been given to pregnant women and infants, there is a potential risk of birth defects and adverse effects on bone growth. It is important to consult with a medical professional to determine if the benefits outweigh the risks.
• You have a history of tendonitis or tendon disorders. This is because there have been cases of tendonitis and tendon disorders reported in relation to the use of cefixime. It is important to be aware of this possibility, especially if you have a preexisting condition.
• You require surgery or dental treatment. This is because cefixime may cause bleeding problems and could increase the risk of bleeding during surgery. It is important to inform your healthcare provider if you are taking cefixime, especially if you are planning to have surgery or dental treatment.

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Unraveling the side effects lurking behind this medications are as follows:

• Diarrhea
• Nausea
• Vomiting
• Abdominal pain
• Urgency to urinate
• Allergic reaction
• Headaches
• Fatigue
• Loss of appetite

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The warnings and precautions associated with Cefixime are:

• Patient with history of hypersensitivity to penicillin and other beta-lactam antibiotics.
• Poor nutritional state.
• History of gastrointestinal disease, particularly colitis.
• Renal and hepatic impairment.
• Children.
• Pregnancy and lactation.

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The drug interactions with cefixime include:

• Anticoagulants (e.g., warfarin) – Cefixime may enhance the anticoagulant effect, increasing the risk of bleeding.
• Probenecid – May increase the levels of cefixime by decreasing its renal clearance.
• Live Bacterial Vaccines (e.g., typhoid vaccine) – Cefixime may reduce the effectiveness of live bacterial vaccines.
• Methotrexate – Cefixime may increase methotrexate levels, leading to increased toxicity.
• Other Antibiotics (e.g., aminoglycosides) – May have additive nephrotoxic effects when used concurrently with cefixime.
• Oral Contraceptives – Cefixime may potentially reduce the effectiveness of oral contraceptives.
• Diuretics (e.g., furosemide) – Concurrent use may increase the risk of nephrotoxicity.
• Calcium-containing Products – Cefixime absorption may be reduced if taken with calcium-containing products.
• Antacids – May reduce cefixime absorption if taken simultaneously.

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The food interactions that should be considered while using Cefixime are:

• No significant interactions with food.
• Taking with food may improve absorption.

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Cefixime is an antibiotic that comes from the cephalosporin group of drugs. It is usually available in tablet or capsule form with 100-500 mg strengths. Store at room temperature, away from direct light, moisture, and heat. Keep the capsules in their original packaging and out of reach of children and pets. Do not store in the bathroom. Do not flush down the toilet or pour into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more information on how to safely discard your medication.

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