Cefalor (125Mg/Ml) 60Ml Suspension

Cefaclor is a beta-lactam antibiotic that belongs to the cephalosporin class. Its primary mechanism of action is inhibiting bacterial cell wall synthesis. Cefaclor specifically targets penicillin-binding proteins (PBPs) located on the bacterial cell wall, which are essential for cross-linking peptidoglycan strands, a crucial component of the cell wall. By binding to these PBPs, Cefaclor disrupts the formation of the peptidoglycan layer, leading to the weakening and eventual rupture of the bacterial cell wall. This cell wall damage results in bacterial cell lysis and death, effectively eliminating the bacteria causing the infection.

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Cefaclor 125mg

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Cephalosporin antibiotic

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Suspension

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The following are the uses of Cefaclor 125mg Syrup/Suspension:

• Used for treating mild to moderate bacterial infections such as ear infections, skin infections, and respiratory tract infections in children.
• Used to control and eradicate bacteria causing these infections.
• Used as an effective antibiotic for children when prescribed by a doctor.
• Used to relieve symptoms associated with the infection, such as fever, pain, and inflammation.
• Used as a short-term treatment option, typically lasting 7-10 days.
• Used to improve overall health and well-being by clearing the bacterial infection.
• Used to prevent the spread of infection to other parts of the body or to other individuals.

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Dose must be taken according to doctor’s advice only; doses given below are suggested as supportive literature for better understanding in some areas of requirements. Adult dose: In case of capsule or oral suspension: Usual dose is 250-500mg after every 8 hours, maximum daily dose in case of severity of infection is 4,000mg daily. Child dose: Child dose of >1 month in case of capsule or oral suspension: Usual dose is 20mg/kg daily in 2 or 3 divided doses; may increase to 40mg/kg daily in divided doses. In case of severity of infection the maximum dose is: 1,000mg daily.

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In the case of an overdose of Cefaclor 125mg Syrup/Suspension, it is important to seek medical advice promptly. Symptoms of overdose may include nausea, vomiting, diarrhea, and abdominal pain. The severity of these symptoms can vary, and they may require specific treatment approaches. It is crucial to provide healthcare professionals with accurate information regarding the amount ingested and the time of overdose to ensure appropriate medical care.

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In the case of a missed dose of Cefaclor 125mg Syrup/Suspension, it is important to administer the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is recommended to take the medication at evenly spaced intervals to maintain an effective level in the body. Consult your healthcare provider if you have any concerns or if you miss multiple doses.

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To administer Cefaclor 125mg Syrup/Suspension, shake the bottle well, use the provided measuring device to draw the prescribed dose, and give it to the patient by mouth once or twice a day, as directed by the healthcare provider, regardless of meals.

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Following are the conditions when Cefaclor 125mg Syrup/Suspension should not be used:

• Should not be used in individuals with a known allergy to Cefaclor or other cephalosporin antibiotics.
• Contraindicated in patients with a history of severe allergic reactions to penicillin, as cross-reactivity may occur.
• Not suitable for patients with severe kidney disease or impairment, as dosage adjustments are necessary.
• Should not be used in patients with a history of gastrointestinal diseases such as colitis or other intestinal disorders.
• Contraindicated in patients with a known or suspected history of phenylketonuria, as some formulations may contain phenylalanine.
• Not recommended for infants below one month of age, as safety and efficacy have not been established.
• Should be avoided in patients with a history of seizures or conditions that increase the risk of seizures, as it may lower the seizure threshold.

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The side effects of Cefaclor 125mg Syrup/Suspension may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Skin rash or itching
• Headache
• Dizziness
• Vaginal yeast infection
• Allergic reactions (hives, difficulty breathing, swelling of the face/throat)

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Following are the precautions and warnings for Cefaclor 125mg Syrup/Suspension:

• Do not use if you are allergic to Cefaclor or any other penicillin-type medications.
• Ensure you complete the full course of medication as prescribed, even if symptoms improve, to prevent the risk of antibiotic resistance.
• Shake the bottle well before each use to ensure a uniform suspension.
• Measure the dose accurately using a calibrated measuring device to ensure the correct amount is administered.
• Store the medication at room temperature, away from direct sunlight and moisture, and keep it out of reach of children.
• Do not share this medication with others, even if their symptoms appear similar.
• If you develop a severe rash, itching, or any other allergic reaction, stop taking the medication and seek immediate medical attention.
• Inform your healthcare provider if you have a history of kidney or liver disease as dose adjustments may be necessary.

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Following are the drug interactions for Cefaclor 125mg Syrup/Suspension:

• Probenecid can decrease the renal excretion of cefaclor, leading to increased plasma concentrations.
• Cefaclor may reduce the effectiveness of oral contraceptives, requiring additional contraceptive measures.
• Concurrent use with anticoagulants like warfarin may increase the risk of bleeding.
• When combined with methotrexate, it can alter methotrexate levels and increase its toxicity.
• Cefaclor may reduce the efficacy of live attenuated vaccines (e.g., measles, mumps, rubella) due to antibody response interference.
• Alcohol consumption may increase the risk of side effects, particularly gastrointestinal disturbances.
• Drugs that affect gastric pH or motility may influence the absorption of cefaclor.

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Following are the food interactions for Cefaclor 125mg Syrup/Suspension:

• Avoid consuming alcohol during the treatment, as it may reduce the effectiveness of Cefaclor and increase the risk of liver-related side effects.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the absorption of Cefaclor, potentially increasing the drug's concentration in the blood.
• Dairy products like milk and yogurt may interfere with the absorption of Cefaclor. It is advisable to take the medication at least one hour before or two hours after consuming dairy.
• High-fat meals might delay the absorption of Cefaclor, leading to a potential reduction in its effectiveness.
• Avoid iron-rich foods or supplements, such as spinach and iron-fortified cereals, as they can decrease the absorption of Cefaclor. It is recommended to separate the medication and iron-rich foods by at least two hours.
• Vitamin C supplements or citrus fruits high in vitamin C may alter the pH of urine, potentially affecting the effectiveness of Cefaclor. It is best to maintain a gap between consuming vitamin C-rich foods and taking the medication.
• Ensure adequate hydration while taking Cefaclor to maintain urine output and prevent the formation of kidney stones.
• Avoid taking Cefaclor with antacids containing aluminum or magnesium, as they can reduce the absorption of the antibiotic.

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Cefaclor 125mg Syrup/Suspension should be stored in a cool, dry area, ideally between 68°F and 77°F (20°C and 25°C), and always keep it away from light and moisture. Ensure the medication remains in its original container, tightly sealed, to maintain its integrity and prevent contamination. It's crucial not to expose the syrup to extreme temperatures or store it in places like bathrooms, near stoves, or on radiators. Always check the expiration date, and if the syrup is past its prime or no longer needed, do not dispose of it via toilet or drain. Contact your pharmacist or healthcare provider for guidance on safe disposal methods. Keep this medication out of children's reach to prevent accidental consumption.

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Following are the quick tips for Cefaclor 125mg Syrup/Suspension:

• Administer the syrup as directed by your doctor, following the prescribed dosage and duration.
• Give the exact prescribed amount using the measuring device provided.
• Shake the bottle vigorously before each use to ensure proper mixing.
• Encourage your child to take the syrup with a full glass of water for better absorption.
• Maintain a consistent daily routine for administering the medication.
• Store the syrup in a cool, dry place, away from direct sunlight and moisture.
• Do not use the medication if it has expired or changed appearance.

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To confirm bacterial infection, go for: Blood Culture Test

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