Cefim DS (200mg/5ml) 30ml Suspension

Cefixime 200mg syrup/suspension is a third-generation cephalosporin antibiotic that exerts its bactericidal effect by inhibiting bacterial cell wall synthesis. It specifically targets penicillin-binding proteins (PBPs), which are essential for cross-linking the peptidoglycan chains in the bacterial cell wall. By binding to these PBPs, Cefixime disrupts the final stages of cell wall synthesis, leading to cell lysis and death. This mechanism of action is effective against a wide range of Gram-positive and Gram-negative bacteria, making Cefixime a valuable treatment option for various bacterial infections.

Cefixime 200mg

Oral third-generation cephalosporin.

Suspension

The following are the uses of Cefixime 200mg Syrup/Suspension:

• Used for treating bacterial infections such as bronchitis, pneumonia, and certain types of ear and throat infections.
• Used for controlling the growth of bacteria and preventing the spread of infection.
• Used for relieving symptoms like fever, cough, and chest pain associated with respiratory tract infections.
• Used for managing acute bacterial exacerbations of chronic bronchitis.
• Used for treating uncomplicated urinary tract infections caused by susceptible bacteria.
• Used for providing targeted treatment for specific bacterial strains, reducing the risk of antibiotic resistance.
• Used for ensuring patient comfort and faster recovery by effectively combating bacterial infections.
• Used for complementing other treatment modalities in managing bacterial infections.

To be administered as per instruction of a healthcare practitioner

In the case of an overdose of Cefixime 200mg Syrup/Suspension, it is important to recognize the potential symptoms. These may include gastrointestinal issues such as nausea, vomiting, and diarrhea. In severe cases, an overdose can lead to neurological symptoms like dizziness, headaches, and confusion. It is crucial to seek medical advice promptly and provide detailed information about the quantity ingested, as this will help determine the appropriate treatment plan.

In the case of a missed dose of Cefixime 200mg Syrup/Suspension, it is important to take the missed dose as soon as possible. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is recommended to set an alarm or use a medication reminder app to help you remember your doses and maintain a consistent treatment routine.

To administer Cefixime 200mg Syrup/Suspension, shake the bottle well, then measure the prescribed dose with an accurate measuring device like a marked measuring cup or oral syringe, and take it orally once or twice a day as directed by your healthcare provider, with or without food, ensuring adherence to the recommended dosage guidelines.

Following are the conditions/situations when Cefixime 200mg Syrup/Suspension should not be used:

• Avoid using in individuals with a known allergy to Cefixime or other cephalosporin antibiotics.
• Not suitable for patients with a history of severe allergic reactions to penicillins.
• Contraindicated in patients with severe kidney disease or those on dialysis.
• Should not be used in infants below 6 months of age.
• Not recommended for individuals with a history of gastrointestinal diseases, especially colitis.
• Avoid using in patients with a known or suspected bacterial infection caused by resistant organisms.
• Not suitable for those with a history of seizures or neurological disorders.

The side effects of Cefixime 200mg Syrup/Suspension may include:

• Diarrhea
• Nausea and vomiting
• Abdominal pain or discomfort
• Skin rash or itching
• Headache
• Dizziness
• Vaginal yeast infection
• Fatigue

Following are the precautions and warnings for Cefixime 200mg Syrup/Suspension:

• Not suitable for individuals with a known allergy to Cefixime or other cephalosporin antibiotics.
• Requires caution in patients with a history of kidney or liver disease, as dosage adjustments may be necessary.
• Should be used with caution in patients with a history of gastrointestinal diseases, especially colitis.
• Avoid using Cefixime if you have a history of severe allergic reactions to any medication.
• Patients may experience dizziness; if affected, avoid driving or operating heavy machinery.
• Always complete the full course of treatment as prescribed, even if symptoms improve, to ensure the infection is fully treated.
• Consult a doctor if symptoms persist or worsen after starting the medication.

Following are the drug interactions for Cefixime 200mg Syrup/Suspension:

• Probenecid can decrease the excretion of Cefixime, leading to increased serum levels.
• Concomitant use with other antibiotics like carbapenems or aminoglycosides may result in altered efficacy or increased side effects.
• Cefixime may reduce the effectiveness of oral contraceptives, requiring additional contraceptive measures.
• The absorption of Cefixime can be decreased by antacids containing aluminum or magnesium, so they should be taken separately.
• Nephrotoxic drugs like aminoglycosides or diuretics may increase the risk of kidney problems when used with Cefixime.
• Cefixime may impact the efficacy of live attenuated vaccines, such as measles or mumps vaccines.
• Concurrent use with other drugs that prolong QT intervals may increase the risk of cardiac arrhythmias.

Following are the food interactions for Cefixime 200mg Syrup/Suspension:

• Avoid consuming excessive amounts of dairy products, as calcium-rich foods can decrease the absorption of Cefixime.
• Grapefruit and grapefruit juice should be consumed sparingly as they can affect the metabolism of Cefixime, potentially increasing its levels in the body.
• Alcohol intake should be limited as it may reduce the effectiveness of Cefixime and increase the risk of liver-related side effects.
• Avoid high-fat meals as they can delay the absorption of Cefixime, potentially affecting its efficacy.
• Iron supplements and iron-rich foods may interfere with Cefixime absorption, so separate them by a few hours.
• Vitamin K-rich foods like leafy greens may reduce the effectiveness of Cefixime, especially in individuals taking anticoagulant medications.
• Probiotics can be beneficial to restore gut flora affected by Cefixime, but consult a healthcare provider for specific recommendations.
• Well-balanced meals are recommended to support overall health during the course of Cefixime treatment.

Cefixime 200mg Syrup/Suspension should be stored in a secure location, preferably a locked medicine cabinet, at room temperature (68°F to 77°F or 20°C to 25°C), with protection from light and moisture. Ensure the medication is kept in its original container, tightly sealed, to maintain its integrity and prevent contamination. It is crucial not to store it in the bathroom or near heat-emitting appliances, as temperature fluctuations can impact its effectiveness. Dispose of any unused or expired syrup responsibly; never pour it down the drain or flush it, as this can cause environmental harm. Consult your pharmacist or local waste management authority for specific disposal guidelines in your area, and always keep medications out of children's reach to prevent accidental consumption.

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Here are the quick tips for Cefixime 200mg Syrup/Suspension:

• Follow your doctor's prescription for the best outcomes.
• Administer the correct dose as directed by your healthcare provider.
• Store the syrup at room temperature, away from excessive heat and moisture.
• Always use the measuring cup/syringe provided to ensure accurate dosing.
• Ensure the medication is out of children's sight and reach for safety.
• Do not share this medication with others, even if their symptoms are similar.
• Consult your doctor if symptoms persist or worsen after starting treatment.