Cefspan (400mg) 5 Capsules

Cefixime is a third-generation cephalosporin antibiotic, widely used to treat bacterial infections of the respiratory tract, urinary tract, skin, and otitis media (middle ear infections) in children. Its effectiveness arises from its ability to interfere with the synthesis of bacterial cell walls, specifically by binding to a target enzyme called penicillin-binding protein (PBP) located within the cell wall. This binding action inhibits PBP activity, which is essential for cell wall formation and maintenance. Consequently, the bacterial cell wall becomes weaker and less stable, leading to its rupture and the demise of the bacterial cells. It's important to note that cefixime's efficacy is limited to treating bacterial infections and is not effective against viral infections like the common cold or influenza. Additionally, some bacteria have developed resistance to cefixime, particularly those with genetic mutations or exposure to other antibiotics. As a result, it is less effective or wholly ineffective against these resistant strains. When considering a course of cefixime, or any antibiotic, it is always advisable to consult with a healthcare professional, who can advise on appropriate dosage, duration of treatment, and potential side effects.

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Cephalosporin Antibiotic

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Capsule

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Unveiling its multifaceted uses and transformative applications as follows:

• Treatment for bacterial infections in the respiratory tract, gonorrhea, and certain uncomplicated urinary tract infections
• Short course of treatment for pneumonia, including community-acquired pneumonia, acute exacerbations of chronic bronchitis, and acute bacterial sinusitis
• Abdominal infections, jaw and genital infections, and bacteremia
• Pediatric uses including otitis media, pneumonia, urinary tract infections, and sinusitis
• Cefixime is a cephalosporin antibiotic and is considered a first-generation cephalosporin
• Cefixime blocks the synthesis of bacterial cell walls and thus inhibits microbial growth
• Consult your healthcare provider to determine if you need this medication for a bacterial infection
• This information is solely for informational purposes and should not be used for diagnosing any medical condition

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Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For Adults-
• Dosage ranges from 400-800 mg a day
• Maximum dose of 1600 mg per day
• For Children-
• Dosage recommended is 10 mg/kg of body weight once a day
• Maximum of 400 mg per day

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An overdose of Cefixime is not expected to produce serious symptoms if taken alone, but it may lead to serious complications when mixed with other drugs or alcohol. Therefore, it is crucial to seek immediate medical attention in case of an overdose of Cefixime. The medical team will need as much information as possible about the overdose, any current medications, and any underlying medical conditions to best treat the patient. The treatment may involve using drugs to counter the effects of the overdose, and in some cases, ventilation may be necessary. The medical team will best be able to determine these needs through their professional expertise and treatment options.

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If you have missed a dose of cefixime, it is important to take it as soon as possible. However, if it is almost time for your next scheduled dose, it is recommended to skip the missed dose and continue with your regular schedule. This is to ensure that you don't double the dose accidentally. If you are unsure about how to proceed, it's best to refer to the instructions provided by your doctor or pharmacist, or contact them directly for advice. It is essential to take cefixime as directed and complete the full course of treatment, as prescribed, to ensure the best results and reduce the risk of resistance. If you have any further questions or concerns about missing a dose of cefixime, don't hesitate to consult with your healthcare provider for guidance specific to your situation.

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Before taking Cefixime, it is important to inform your doctor about any medical conditions you may have and any other medications you are currently taking. Cefixime is usually taken every 12 hours or as directed by the physician. It is advisable to take each dose with a full glass of water, with or without food. To achieve the best effect, it is necessary to complete the full course of treatment, even if symptoms improve. Some side effects of this medication may include nausea, loose stools or vomiting, diarrhea, urgent repeated or painful urination, and an allergic reaction such as hives, swelling of the lips, face, throat, or tongue. Serious side effects that require medical attention include difficulty breathing or shortness of breath, changes in vision or eye pain, severe allergic reaction, jaundice (yellowing of the skin or eyes), muscle weakness, pain, or tenderness, and seizures. This is not the complete list of side effects, and others may occur. It is essential to only use this medication according to the prescription and for the prescribed duration. Please consult your physician if you have any questions or concerns regarding your condition or this medication.

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Discerning instances where this medication may not be appropriate:

• You are allergic to cefixime or any other ingredients in the medication. If you have had a severe allergic reaction to penicillin, you could also be allergic to cefixime. It is important to note that allergies can also manifest themselves in a variety of ways including hives, itching, or difficulty in breathing. If this happens after taking cefixime, it is important to seek medical attention.
• You have a history of liver disease or a severe infection. This is because cefixime can cause abnormalities in liver function tests and can increase the risk of liver failure. This is especially the case for those who have a history of liver disease or a compromised immune system.
• You are pregnant or breastfeeding. This is because there are no well-controlled studies that demonstrate the safety of cefixime in pregnant women and infants. Although cefixime has been given to pregnant women and infants, there is a potential risk of birth defects and adverse effects on bone growth. It is important to consult with a medical professional to determine if the benefits outweigh the risks.
• You have a history of tendonitis or tendon disorders. This is because there have been cases of tendonitis and tendon disorders reported in relation to the use of cefixime. It is important to be aware of this possibility, especially if you have a preexisting condition.
• You require surgery or dental treatment. This is because cefixime may cause bleeding problems and could increase the risk of bleeding during surgery. It is important to inform your healthcare provider if you are taking cefixime, especially if you are planning to have surgery or dental treatment.

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Unraveling the side effects lurking behind this medications are as follows:

• Diarrhea
• Nausea
• Vomiting
• Abdominal pain
• Urgency to urinate
• Allergic reaction
• Headaches
• Fatigue
• Loss of appetite

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Patients should consider these precautions and warnings before using the medication:

• Individuals with a history of hypersensitivity to penicillin and other beta-lactam antibiotics should exercise caution.
• Those in poor nutritional states or with a history of gastrointestinal diseases, particularly colitis, need special consideration.
• Careful monitoring is required for patients with renal and hepatic impairment.
• Extra caution should be taken when administering the medication to children.
• Special attention is needed during pregnancy and lactation.

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Drug interactions with cefixime include:

• Anticoagulants (e.g., warfarin) (may increase the risk of bleeding- monitor INR)
• Probenecid (may increase cefixime levels by decreasing renal excretion)
• Other antibiotics (e.g., aminoglycosides) (may have additive effects or alter efficacy)
• Oral contraceptives (no significant interaction, but alternative contraception is recommended)
• Vaccines (e.g., live bacterial vaccines) (may reduce the effectiveness of live vaccines)
• Antacids and supplements (e.g., calcium, iron) (may reduce absorption of cefixime- take cefixime separately)
• Diuretics (e.g., furosemide) (may alter renal function and affect cefixime levels)

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The food interactions that should be considered while using Cefixime are:

• Avoid alcohol as it can increase the risk of side effects and interact with the medication
• High-fat meals may impact the absorption and effectiveness of the medication
• Foods high in potassium may interact with the medication and cause imbalances

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Cefixime is an antibiotic that comes from the cephalosporin group of drugs. It is usually available in tablet or capsule form with 100-500 mg strengths. It should be handled and stored properly to keep it safe and prevent unauthorized access. Store in a cool, dry place away from direct sunlight and moisture, at room temperature (15-25°C). Keep it out of reach of children and pets to prevent accidental ingestion. Do not store in bathrooms or areas prone to humidity. Properly dispose of any unused or expired medication according to local regulations or return it to a pharmacy take-back program to ensure safe disposal. Avoid flushing it down the toilet or pouring it into drains unless instructed to do so.

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