Chlorohist Syp 120Ml

Chlorohist Syp 120Ml

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  • Generic Name

    Ammonium Chloride, Citrate B.P, Diphenhydramine Hydrochloride B.P.

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Ammonium Chloride promotes the excretion of excess acid by the kidneys, helping to maintain the body's acid-base balance. Citrate B.P., or citric acid, acts as a buffer and chelating agent, binding to and neutralizing excess acid in the body. Diphenhydramine Hydrochloride B.P., an antihistamine, blocks the action of histamine receptors in the brain and peripheral tissues, reducing the production of stomach acid and providing sedative effects to suppress the cough reflex.

  • Ingredients

    Ammonium Chloride, Citrate B.P, Diphenhydramine Hydrochloride B.P.

  • Drug Class

    Expectorant and Antihistamine

  • Dosage Form

    Suspension

  • Uses

    The following are the uses of Ammonium Chloride, Citrate B.P, Diphenhydramine Hydrochloride B.P. Syrup/Suspension:

    • Used for its expectorant and cough suppressant properties in treating respiratory tract infections and coughs.
    • Used as an antihistamine to relieve allergic symptoms such as sneezing, runny nose, and itching.
    • Used to reduce symptoms of motion sickness and induce mild sedation.
    • Used to treat mild to moderate pain, especially when combined with other analgesics.
    • Used as an ingredient in cough and cold medications to provide temporary relief from symptoms.
    • Used in eye drops to relieve redness and irritation caused by allergies or minor irritants.
    • Used as a topical anesthetic in some oral care products to numb mouth and throat tissues.
    • Used in veterinary medicine to treat various conditions in animals, including respiratory issues and allergies.
  • In case of Overdose

    In the case of an overdose of Ammonium Chloride, Citrate B.P., or Diphenhydramine Hydrochloride B.P. Syrup/Suspension, individuals may experience various symptoms. These can include gastrointestinal distress, such as nausea, vomiting, and abdominal pain, as well as potential central nervous system effects like drowsiness, confusion, and in severe cases, seizures. Prompt medical evaluation is necessary to manage these symptoms effectively and prevent any long-term complications.

  • Missed Dose

    In the case of a missed dose of Ammonium Chloride, administer it as soon as you remember, but skip it if it's almost time for the next dose. For Citrate B.P., take the missed dose as soon as possible, but do not double the dose. If you miss a dose of Diphenhydramine Hydrochloride, take it as soon as you remember, but avoid taking it if it's close to the next scheduled dose. Always consult your healthcare provider if you have concerns about missed doses.

  • How To Use

    To administer the Ammonium Chloride, Citrate B.P, Diphenhydramine Hydrochloride B.P. Syrup/Suspension, shake the bottle vigorously to ensure the contents are well-mixed, then accurately measure the prescribed dose using an appropriate measuring device like a marked measuring cup or oral syringe, and administer it orally, following the dosage instructions provided by your healthcare professional or as indicated on the medication's label.

  • When Not to Use

    Here are the conditions and situations when Ammonium Chloride, Citrate B.P, Diphenhydramine Hydrochloride B.P. Syrup/Suspension should not be used:

    • Do not use if you have a known allergy or hypersensitivity to any of the ingredients, including ammonium chloride, citric acid, or diphenhydramine hydrochloride.
    • Contraindicated in patients with bronchial asthma, chronic obstructive pulmonary disease (COPD), or other respiratory conditions that may be aggravated.
    • Should not be used in patients with narrow-angle glaucoma.
    • Avoid using this medication if you have a blockage in your stomach or intestines, or if you have difficulty urinating due to an enlarged prostate.
    • Not recommended for individuals with a history of seizures or epilepsy.
    • Do not use in newborns, premature babies, or infants due to the risk of serious side effects.
    • Contraindicated in patients with a history of heart disease, high blood pressure, or cardiovascular disorders.
    • Should not be used in individuals with liver or kidney disease.
    • Avoid using this medication if you are taking monoamine oxidase inhibitors (MAOIs) or have taken them within the last 14 days.
  • Side Effects

    The side effects of Ammonium Chloride, Citrate B.P, Diphenhydramine Hydrochloride B.P. Syrup/Suspension may include:

    • Nausea and vomiting
    • Dry mouth and throat
    • Drowsiness or sedation
    • Blurred vision
    • Constipation or diarrhea
    • Increased heart rate
    • Allergic reactions, such as skin rash or itching
  • Precautions & Warnings

    Following are the precautions and warnings for Ammonium Chloride, Citrate B.P, Diphenhydramine Hydrochloride B.P. Syrup/Suspension:

    • Do not use this medication if you are allergic to any of its ingredients, including ammonium chloride, citrate, or diphenhydramine hydrochloride.
    • Patients with kidney problems should use this medication with caution and under medical supervision, as it may need dosage adjustments.
    • Avoid alcohol consumption while taking this medication, as it can increase the risk of side effects, including dizziness and drowsiness.
    • Do not drive or operate heavy machinery if you experience drowsiness or impaired coordination as a side effect.
    • Consult a doctor before use if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of this medication during these periods is not well-established.
    • Keep out of reach of children. In case of accidental overdose, seek immediate medical attention.
    • This medication may cause sensitivity to sunlight; limit sun exposure and use protective measures when outdoors.
    • Discontinue use and consult a healthcare professional if you develop a skin rash, itching, or other allergic reactions.
  • Drug Interactions

    Following are the drug interactions for Ammonium Chloride, Citrate B.P, Diphenhydramine Hydrochloride B.P. Syrup/Suspension:

    • Alcohol and other central nervous system (CNS) depressants, such as opioids or benzodiazepines, may enhance the sedative effects of Diphenhydramine, leading to increased drowsiness and impaired motor skills.
    • Monoamine oxidase inhibitors (MAOIs) should be avoided with Diphenhydramine due to the risk of severe side effects, including increased blood pressure and hyperthermia.
    • Drugs that prolong the QT interval, such as certain antiarrhythmics or antipsychotics, may interact with Diphenhydramine, increasing the risk of cardiac arrhythmias.
    • Antacids containing aluminum or magnesium may decrease the absorption of Ammonium Chloride, reducing its effectiveness.
    • Citrate B.P. may interact with calcium-containing products, such as calcium supplements or dairy products, leading to the formation of insoluble calcium citrate complexes and reduced absorption of both substances.
    • Diphenhydramine can reduce the effectiveness of certain medications used for Parkinson's disease, such as Levodopa, by blocking its action at the brain receptors.
    • The Syrup/Suspension may also interact with certain antibiotics, such as Erythromycin, potentially increasing the risk of cardiac side effects.
  • Food Interactions

    Following are the food interactions for Ammonium Chloride, Citrate B.P, Diphenhydramine Hydrochloride B.P. Syrup/Suspension:

    • Grapefruit juice should be used cautiously with Diphenhydramine as it can inhibit the CYP450 enzyme, leading to increased drug levels and potential side effects.
    • Alcohol may intensify the sedative effects of Diphenhydramine, causing increased drowsiness and impaired coordination.
    • Caffeine-containing products may counteract the sedative effects of Diphenhydramine, reducing its effectiveness for sleep or allergy relief.
    • Consuming a high-fat meal with this medication may slightly delay the absorption of Diphenhydramine, but it is generally well-tolerated.
    • Avoid consuming excessive amounts of acidic foods or beverages, as Citrate B.P. may already increase urine acidity.
    • Spicy foods or hot beverages may irritate the throat, especially if the medication causes dryness or a sore throat as a side effect.
    • Dairy products may interfere with the absorption of certain medications, but this is not a significant concern with Diphenhydramine.
  • Storage/Disposal

    Ammonium Chloride, Citrate B.P., and Diphenhydramine Hydrochloride B.P. Syrup/Suspension should be stored in a controlled environment, preferably in a cool, dry place away from sunlight and moisture. Keep the medication tightly sealed in its original container to maintain its integrity. Avoid storing it in hot or humid areas like bathrooms or kitchens. Regularly check the expiration date, and dispose of any expired or unused medication responsibly. Do not dispose of it in wastewater or regular trash; consult a pharmacist or local waste management guidelines for appropriate disposal methods. Ensure the medication is stored safely, out of the reach of children, to prevent accidental consumption.

  • Quick Tips, if any

    Following are the quick tips for Ammonium Chloride, Citrate B.P, Diphenhydramine Hydrochloride B.P. Syrup/Suspension:

    • Always consult your doctor or pharmacist before use, especially if you have any medical conditions or are taking other medications.
    • Shake the bottle vigorously to ensure a uniform mixture before each use.
    • Administer the syrup with a measuring cup or oral syringe for accurate dosing.
    • Take the syrup with water, and avoid consuming it with acidic beverages or dairy products.
    • Store the medication at room temperature, away from direct sunlight and moisture.
    • Do not use if the syrup changes color or develops an unusual odor.
    • Dispose of any unused or expired medication properly; do not flush it down the toilet.

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