Expectorant-E 120ml Cough Syrup

Aminophylline, a bronchodilator, relaxes airway smooth muscles by inhibiting phosphodiesterase, leading to increased intracellular cAMP. Ammonium chloride acts as an expectorant by reducing mucus viscosity, facilitating its clearance. Diphenhydramine, an antihistamine, blocks H1 receptors, providing symptomatic relief from allergies and suppressing the cough reflex. Together, these components synergistically contribute to airway patency, mucus clearance, and cough control.

Aminophylline, ammonium chloride, diphenhydramine

Aminophylline:

Suspension

The following are the uses of Aminophylline, ammonium chloride, diphenhydramine Syrup/Suspension:

• Used for treating respiratory conditions such as asthma, chronic bronchitis, and emphysema to relax the airways and improve breathing.
• Used for reducing excess fluid in the body, particularly in conditions like congestive heart failure and certain types of edema.
• Used for managing symptoms of allergies, including allergic rhinitis, by reducing sneezing, runny nose, and itching.
• Used for treating motion sickness and vertigo to alleviate nausea, vomiting, and dizziness.
• Used for providing short-term relief from insomnia and inducing sleep in cases of difficulty falling asleep.
• Used for suppressing non-productive coughs and reducing coughing fits, especially in cases of upper respiratory tract infections.
• Used for treating mild to moderate pain and reducing fever in combination with other analgesics.
• Used for providing symptomatic relief in various conditions with its combined anti-inflammatory, bronchodilator, and sedative properties.

In the case of an overdose of Aminophylline, ammonium chloride, or diphenhydramine syrup/suspension, prompt medical attention is required. Symptoms may include rapid or irregular heartbeat, nausea, vomiting, seizures, and confusion. Treatment involves managing these symptoms, providing supportive care, and possibly administering specific antidotes to counteract the effects of the overdose. Quick action is essential to ensure the best possible outcome.

In the case of a missed dose of Aminophylline, it is advisable to take the missed dose as soon as possible. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. For ammonium chloride and diphenhydramine, if you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

To administer Aminophylline, ammonium chloride, and diphenhydramine syrup/suspension, shake the bottle well, measure the prescribed dose with an oral syringe or measuring cup, and take it orally as directed by your healthcare professional, typically every 6-8 hours or as instructed, ensuring a consistent dosage for optimal therapeutic benefits.

Here are the situations when Aminophylline, ammonium chloride, and diphenhydramine Syrup/Suspension should not be used:

• Should not be used in patients with a known allergy to any of the active ingredients, including aminophylline, ammonium chloride, or diphenhydramine.
• Contraindicated in patients with narrow-angle glaucoma.
• Not suitable for individuals with severe heart diseases, such as cardiac arrhythmias or recent heart attack.
• Should not be used in patients with severe high blood pressure.
• Contraindicated in patients with bronchial asthma or those who are experiencing an asthma attack.
• Not recommended for individuals with a blockage in the stomach or intestines.
• Should not be used in patients with severe liver or kidney disease.
• Contraindicated during breastfeeding, as the medication may pass into breast milk.
• Should be avoided in patients with an overactive thyroid gland.
• Not suitable for individuals with a history of seizures or epilepsy.
• Should not be used in patients with urinary retention or an enlarged prostate.
• Avoid in patients with severe respiratory diseases or conditions like emphysema or chronic bronchitis.

The side effects of Aminophylline, Ammonium Chloride, and Diphenhydramine Syrup/Suspension may include:

• Nausea and vomiting
• Restlessness or nervousness
• Rapid or irregular heartbeat
• Dizziness or lightheadedness
• Difficulty in urination
• Dry mouth or throat
• Blurred vision
• Allergic reactions such as skin rash, itching, or swelling.

Following are the precautions and warnings for Aminophylline, ammonium chloride, and diphenhydramine Syrup/Suspension:

• This medication should be used with caution in patients with heart conditions, as it may cause irregular heart rhythms.
• Patients with liver or kidney disease should be closely monitored, as the dosage may need adjustment.
• It can cause nervousness, restlessness, or dizziness, so caution should be exercised when performing tasks requiring mental alertness.
• Avoid alcohol consumption while taking this medication, as it may increase the risk of side effects.
• Do not use this medication if you have a history of seizures, as it may lower the seizure threshold.
• Patients with narrow-angle glaucoma should use this medication with caution, as it may worsen the condition.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as it may have potential risks for the fetus or infant.
• Always follow the prescribed dosage and do not exceed the recommended duration of treatment.

Following are the drug interactions for Aminophylline, Ammonium Chloride, and Diphenhydramine Syrup/Suspension:

• Aminophylline may interact with other medications that stimulate the central nervous system, such as caffeine, ephedrine, and other xanthines, potentially causing increased side effects like nervousness, rapid heartbeat, and insomnia.
• Concomitant use with certain antibiotics (e.g., ciprofloxacin, clarithromycin) can inhibit the metabolism of Aminophylline, leading to elevated levels and potential toxicity.
• Diphenhydramine can enhance the sedative effects of central nervous system depressants like benzodiazepines, alcohol, and opioids, requiring dosage adjustments.
• It may reduce the effectiveness of certain medications for asthma or chronic obstructive pulmonary disease (COPD), such as bronchodilators and inhaled corticosteroids.
• Diphenhydramine can also decrease the effectiveness of certain antidepressants, including monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants.
• Ammonium Chloride may interact with medications that affect urine production or acid-base balance, such as diuretics and certain medications for heart failure.
• It may decrease the absorption of certain medications when taken concurrently, including some antibiotics and thyroid medications.

Following are the food interactions for Aminophylline, ammonium chloride, diphenhydramine Syrup/Suspension:

• Citrus fruits, especially grapefruit and its juice, should be avoided as they can interfere with the metabolism of diphenhydramine, potentially increasing its levels in the body and causing prolonged drowsiness.
• Alcohol should be consumed with caution as it can enhance the sedative effects of diphenhydramine, leading to increased drowsiness and impaired coordination.
• Caffeine-containing beverages should be limited as they may counteract the calming effects of diphenhydramine and can cause restlessness and insomnia.
• Foods high in fat may slow down the absorption of the medication, affecting its onset of action.
• Avoid large meals before taking this medication, as it can delay gastric emptying and affect the absorption of the drug.
• Avoid excessive salt intake, as ammonium chloride can increase urine output and may lead to electrolyte imbalances.
• Consult a healthcare professional regarding dietary restrictions, especially for individuals with kidney issues, as this medication may require adjustments in potassium-rich foods.

Aminophylline, ammonium chloride, and diphenhydramine Syrup/Suspension should be stored in a cool, dry area, preferably at room temperature, shielded from direct sunlight and moisture. The medication should be tightly sealed in its original container to maintain its integrity and prevent contamination. Avoid storage in humid environments like bathrooms or near heat-emitting appliances to preserve its effectiveness. Proper disposal of unused or expired syrup is crucial; refrain from flushing it down the toilet or pouring it into drains. Consult a pharmacist or healthcare professional for appropriate disposal practices, and ensure the medication is kept away from children to prevent accidental consumption.

Following are the quick tips for Aminophylline, Ammonium Chloride, Diphenhydramine Syrup/Suspension:

• Consult a healthcare professional for personalized advice and dosage instructions.
• Ensure you understand the specific usage and precautions for your condition.
• Always read the medication label and follow the prescribed dosage and administration instructions.
• Store the medication as directed, away from direct sunlight and moisture.
• Do not share your medication with others, even if their symptoms seem similar.
• If you experience any adverse effects or allergic reactions, seek medical attention promptly.
• Regularly review your medication with your healthcare provider to ensure its ongoing effectiveness.