CLARIDERM PLUS CREAM

Glycolic Acid works by promoting exfoliation and accelerating cell turnover. It penetrates the skin and weakens the bonds that hold dead skin cells together, allowing them to be shed more easily. This process helps to remove the outer layer of skin, reducing the appearance of fine lines, wrinkles, and hyperpigmentation. Hydrocortisone, on the other hand, is a synthetic corticosteroid that mimics the effects of naturally occurring hormones in the body. When applied topically, it exhibits anti-inflammatory and immunosuppressive properties. Hydrocortisone binds to corticosteroid receptors in the skin, inhibiting the release of inflammatory mediators and reducing redness, itching, and swelling associated with various skin conditions. This mechanism helps to alleviate inflammation, soothe irritated skin, and suppress immune responses that contribute to skin discomfort.

Alpha-hydroxy acid, Corticosteroid.

Cream

The following are the uses of Glycolic Acid, Hydrocortisone Cream:

• Used for chemical peels to improve skin texture and reduce signs of aging.
• Used for treating various skin conditions like psoriasis, eczema, and dermatitis.
• Used for reducing inflammation and redness caused by acne.
• Used for exfoliating the skin, removing dead skin cells, and promoting cell renewal.
• Used for improving the appearance of scars and stretch marks.
• Used for brightening and evening out skin tone, fading dark spots and hyperpigmentation.
• Used for moisturizing and hydrating dry, irritated skin.
• Used for enhancing the effectiveness of other skincare products by improving absorption.

In the case of an overdose of Glycolic Acid, one may experience skin irritation, redness, and peeling. Higher concentrations can lead to severe chemical burns. For Hydrocortisone Cream, while generally safe, overuse can cause skin thinning, bruising, and changes in skin pigmentation. If ingested, it may result in nausea, vomiting, and stomach irritation. It is important to seek medical advice if any adverse effects are experienced.

In the case of a missed dose of Glycolic Acid, it is generally advised to apply the medication as soon as you remember. However, if it's almost time for your next application, skip the missed dose and resume your regular schedule. Avoid applying extra medication to make up for the missed dose. For Hydrocortisone Cream, if you forget to apply it, apply it as soon as you remember, but do not apply extra medication to compensate for the missed application. It's important to maintain a consistent routine with these medications for optimal results.

To use Glycolic Acid, gently apply a thin layer to the affected area of the skin once daily, preferably at bedtime, as directed by your healthcare provider, and follow with a thin application of Hydrocortisone Cream to reduce skin irritation.

Here are the conditions or situations when Glycolic Acid and Hydrocortisone Cream should not be used:

• Avoid using Glycolic Acid on broken or severely irritated skin.
• Do not use if you are allergic to any ingredients in the product, especially Glycolic Acid or related compounds.
• Not recommended for individuals with open wounds or active skin infections in the area of application.
• Avoid using Hydrocortisone Cream on skin conditions caused by infections, such as cold sores, shingles, or chickenpox.
• Should not be used on skin conditions that are not responsive to Hydrocortisone, or in cases where the condition worsens after using the cream.
• Avoid applying near the eyes, inside the nose or mouth, or on sensitive areas of the skin without medical advice.
• Contraindicated for individuals with a history of allergic reactions to corticosteroids or any of the cream's components.
• Not suitable for long-term use without medical supervision, as prolonged use can lead to skin thinning and other adverse effects.
• Avoid using on large areas of the body or under occlusive dressings, as this may increase the risk of systemic absorption and side effects.

The side effects of using Glycolic Acid, Hydrocortisone Cream may include:

• Skin irritation or redness
• Dryness or peeling of the skin
• Stinging or burning sensation during application
• Increased sensitivity to sunlight (photosensitivity)
• Thinning of the skin with prolonged use of hydrocortisone
• Allergic reactions such as itching, swelling, or rash
• Acne or breakouts with prolonged use of hydrocortisone
• Contact dermatitis or worsening of skin conditions
• In rare cases, systemic absorption of hydrocortisone leading to hormonal imbalances

Following are the precautions and warnings for Glycolic Acid, Hydrocortisone Cream:

• Avoid contact with eyes, mouth, and other mucous membranes. In case of accidental contact, rinse thoroughly with water.
• Do not use on open wounds, infected, or severely damaged skin.
• This cream may cause skin irritation or dryness; if irritation persists, consult a healthcare professional.
• Not recommended for long-term use without medical supervision.
• Do not use if you are allergic to any of the ingredients, especially Glycolic Acid or Hydrocortisone.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
• If you are pregnant or breastfeeding, consult a healthcare professional before use.

Following are the drug interactions for Glycolic Acid, Hydrocortisone Cream:

• Glycolic acid may increase skin sensitivity, so concurrent use with other topical medications like retinoids or benzoyl peroxide may cause irritation or dryness.
• Topical corticosteroids like hydrocortisone can be absorbed systemically, potentially reducing the effectiveness of immunosuppressant drugs.
• Hydrocortisone may interact with oral corticosteroids, increasing the risk of adrenal suppression.
• Avoid using other topical corticosteroids simultaneously to prevent additive effects and skin thinning.
• The cream may reduce the effectiveness of live vaccines, so separate their administration by at least two weeks.
• Anticoagulants might increase the risk of bruising or bleeding at the application site.
• Glycolic acid can increase skin photosensitivity, so sun exposure should be minimized and sunscreen use is recommended.

Following are the food interactions:

• Glycolic acid may increase the skin’s sensitivity to the sun, so it’s important to avoid excessive sun exposure or use sunscreen when consuming sun-related foods or spending time outdoors.
• Avoid using glycolic acid with food products that may irritate the skin, such as spicy or acidic foods, as they can increase skin sensitivity.
• When using hydrocortisone cream, avoid consuming foods high in salt, as it can affect fluid retention and exacerbate side effects like swelling.
• Alcohol should be avoided while using hydrocortisone cream, as it may increase the risk of skin irritation and dehydration.
• Avoid foods rich in vitamin C or other acidic foods that may irritate the skin when combined with glycolic acid or hydrocortisone cream.

Glycolic Acid and Hydrocortisone Cream should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the cream inside its original packaging, tightly sealed, to maintain its integrity and prevent contamination. Avoid exposing the cream to extreme temperatures by not storing it in hot places like near stoves or inside bathrooms with steam. Always check the expiration date, and for proper disposal, consult a pharmacist or healthcare provider to ensure responsible environmental practices. Keep the cream out of children's reach to prevent accidental contact or ingestion.

Following are the quick tips for this Cream:

• Apply to clean, dry skin as directed by your dermatologist.
• Use sunscreen during the day to protect treated skin.
• Avoid sun exposure and wear protective clothing when outdoors.
• Start with a lower concentration and gradually increase as tolerated.
• Patch test a small area first to check for skin sensitivity.
• Do not use on broken or irritated skin.
• Store in a cool, dry place, away from direct sunlight.
• Apply a thin layer to affected areas 2-3 times daily or as directed by your doctor.
• Gently massage the cream into the skin until it is absorbed.
• Wash your hands before and after application to avoid spreading.
• Avoid using on the face, eyes, or sensitive areas unless prescribed.
• Do not cover treated areas with bandages or tight clothing.
• Store the cream at room temperature, away from moisture and heat.
• Consult your doctor if symptoms persist or worsen after a few days of use.