Clinda-T (1.2/0.025%) 20g Topical Gel

Clindamycin, a component of the Clindamycin, Pycnogenol Gel, primarily exerts its antibacterial activity by binding to the 50S subunit of the bacterial ribosome. This binding interferes with protein synthesis, specifically by preventing the elongation of peptide chains, which is crucial for bacterial growth and replication. Clindamycin is particularly effective against anaerobic bacteria and certain gram-positive bacteria, making it valuable in treating skin infections caused by susceptible organisms. Pycnogenol, derived from French maritime pine bark extract, is known for its antioxidant and anti-inflammatory properties. In the gel formulation, Pycnogenol may contribute to reducing inflammation and oxidative stress in the skin, potentially enhancing the overall therapeutic effect and supporting skin healing.

Clindamycin, Pycnogenol

Lincosamide antibiotic

gel

The following are the uses of Clindamycin, Pycnogenol Gel:

• Used for treating acne and reducing inflammation.
• Used for soothing irritated skin and promoting healing.
• Used for improving overall skin texture and reducing redness.
• Used for managing rosacea symptoms and calming skin.
• Used for post-procedure care to reduce swelling and speed up recovery.
• Used for its antioxidant properties to protect the skin from environmental damage.
• Used for enhancing the effectiveness of other skincare products when used in combination.
• Used for addressing mild to moderate bacterial skin infections.

In the case of an overdose of Clindamycin, symptoms may include severe diarrhea, abdominal pain, and skin rashes. It is important to seek medical advice if you suspect an overdose. Pycnogenol Gel overdose may result in localized skin irritation, redness, and itching. If ingested, it could lead to gastrointestinal discomfort. Promptly contact a healthcare professional for guidance if an overdose is suspected with either of these medications.

In the case of a missed dose of Clindamycin, apply the medication as soon as you remember. If it's almost time for your next dose, skip the missed application and continue with your regular schedule. Do not apply extra gel to make up for the missed dose. For Pycnogenol Gel, if you forget to apply it, apply it as soon as you remember, but if it's close to the time for your next application, skip the missed dose and continue with your regular routine. Do not double the dose to compensate for the missed application.

To apply Clindamycin, Pycnogenol Gel, clean and dry the affected skin area, then gently massage a thin layer of the gel onto the skin, ensuring complete coverage, and allow it to absorb, typically applying it twice daily or as directed by your healthcare professional.

Following are the conditions/situations when Clindamycin, Pycnogenol Gel should not be used:

• Avoid using if you have a known allergy or sensitivity to clindamycin, pycnogenol, or any other ingredients in the gel.
• Do not use if you have a history of gastrointestinal diseases, especially those with a history of antibiotic-associated colitis.
• Not suitable for individuals with a history of severe liver or kidney impairment.
• Should not be applied to open wounds, broken skin, or severe skin injuries.
• Avoid using near the eyes, mouth, or other mucous membranes.
• Do not use if you are pregnant or breastfeeding, unless directed by a healthcare professional.
• Not recommended for children without medical advice.
• Avoid using if you have a history of allergic reactions to other antibiotics, especially lincomycin, as cross-sensitivity may occur.

The side effects of Clindamycin and Pycnogenol Gel may include:

• Skin irritation or redness at the application site
• Dryness or peeling of the skin
• Itching or burning sensation
• Acne or rash
• Allergic reactions (skin redness, swelling, or hives)
• Gastrointestinal discomfort (nausea, vomiting)
• Diarrhea
• Joint pain or muscle stiffness

Following are the precautions and warnings for Clindamycin, Pycnogenol Gel:

• Avoid contact with eyes, nose, and mouth. In case of accidental contact, rinse thoroughly with water.
• Do not use the gel if you are allergic to any of its ingredients. Always check the ingredient list before application.
• This medication is for external use only. Do not swallow or ingest.
• Wash your hands before and after applying the gel to avoid contamination and spreading of bacteria.
• Avoid using other topical products on the same area without medical advice, as they may interact or cause skin irritation.
• If you are pregnant or breastfeeding, consult your doctor before using this medication.
• Discontinue use and seek medical attention if you experience severe skin reactions, such as burning, st, or severe irritation.

Following are the drug interactions for Clindamycin, Pycnogenol Gel:

• Concomitant use with other topical antibiotics may increase the risk of skin irritation or allergic reactions.
• Benzoyl peroxide or other harsh topical acne treatments may increase irritation or dryness when used with clindamycin and pycnogenol gel.
• Oral contraceptives may have reduced effectiveness when combined with clindamycin, especially in combination with other acne treatments.
• Topical corticosteroids may exacerbate skin thinning when used in combination with clindamycin.
• Alcohol-based products may increase skin dryness or irritation when used with the gel, leading to increased discomfort.
• Vitamin A derivatives like tretinoin or isotretinoin may increase the risk of skin dryness or irritation when used with clindamycin and pycnogenol gel.

Following are the food interactions for Clindamycin and Pycnogenol Gel:

• Consuming alcohol with Clindamycin may cause stomach discomfort, nausea, and vomiting. It is advisable to limit or avoid alcohol during the treatment.
• Dairy products like milk, yogurt, and cheese may interfere with the absorption of Clindamycin. It is best to take the medication at least 1 hour before or 2 hours after consuming dairy.
• Grapefruit and grapefruit juice should be avoided as they can increase the levels of Clindamycin in the blood, potentially leading to an increased risk of side effects.
• Pycnogenol Gel may be less effective when applied immediately after a meal, especially if the meal contains high levels of fats or oils, as it can affect the absorption of the gel.
• Some foods rich in antioxidants, like berries and dark chocolate, may enhance the effects of Pycnogenol due to their synergistic properties.
• Avoid spicy foods when using Clindamycin, as it may irritate the stomach and exacerbate any gastrointestinal side effects.
• Caffeinated beverages might increase the side effects of Clindamycin, so it's best to limit their consumption.

Clindamycin, Pycnogenol Gel should be stored in a cool and dry place, preferably at room temperature, away from direct exposure to sunlight, heat, or moisture. The original container should be tightly sealed to maintain its integrity and effectiveness. It is crucial not to store the gel in bathrooms or near sinks as humidity can impact its quality. Always check the expiration date before use, and dispose of any expired or unused gel responsibly, avoiding flushing or pouring it down the drain. Contact your pharmacist or healthcare provider for appropriate disposal guidelines, and keep the medication out of children's reach to prevent accidental ingestion. Proper storage and disposal practices ensure the safety and efficacy of the gel.

Following are the quick tips for Clindamycin, Pycnogenol Gel:

• Apply a thin layer of the gel to the affected area as directed by your healthcare provider.
• Ensure the area is clean and dry before application.
• Wash your hands before and after applying the gel to avoid contamination.
• Use the gel as a spot treatment, focusing on affected areas, and avoid applying it to healthy skin.
• Do not cover the treated area with bandages or tight clothing to allow it to breathe.
• Store the gel at room temperature, away from direct sunlight and moisture.
• Consult your doctor if you experience severe irritation or no improvement after several days of use.