Clioquinol (3%) 20g Cream

Clioquinol cream works primarily by inhibiting the growth and reproduction of certain types of fungi and bacteria. It achieves this by interfering with their cellular metabolism and disrupting essential microbial processes. The active ingredient, clioquinol, is believed to bind to key enzymes involved in microbial energy production, such as those in the electron transport chain. This interference leads to a depletion of energy reserves, ultimately causing the death or inhibition of the growth of the microorganisms responsible for various skin infections. Additionally, clioquinol may possess anti-inflammatory properties, contributing to its overall therapeutic effect in treating skin conditions.

Clioquinol

Antifungal/Antibacterial Cream

Cream

The following are the uses of Clioquinol Cream:

• Used for treating skin infections like athlete's foot, ringworm, and jock itch.
• Used for relieving itching, redness, and discomfort associated with these fungal infections.
• Used to stop the growth and spread of fungi on the skin.
• Used for treating tinea versicolor, a fungal infection causing discolored patches on the skin.
• Used for managing inflammation and itching in certain skin conditions.
• Used as an antiseptic to prevent bacterial infections in minor cuts or scrapes.
• Used for maintaining skin hygiene and preventing fungal infections in humid environments.

In the case of an overdose of Clioquinol Cream, it is important to take prompt action. Firstly, thoroughly wash the affected area with water to remove any excess cream. Then, seek medical advice from a healthcare professional or contact a poison control center for further guidance. Keep the cream out of reach of children to prevent accidental ingestion or misuse.

In the case of a missed dose of Clioquinol Cream, it is important to apply the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra cream to make up for the missed application. If you miss multiple doses, consult your healthcare provider for guidance on how to adjust your dosage schedule to ensure optimal treatment. It is essential to maintain a consistent routine to maximize the effectiveness of this medication.

To apply Clioquinol Cream, clean and dry the affected skin area, then apply a thin layer of the cream, gently rubbing it into the skin, usually twice a day or as directed by your healthcare professional.

Following are the conditions/situations when Clioquinol Cream should be avoided:

• Do not use if you are allergic to Clioquinol or any other similar medications.
• Avoid using on open wounds, burns, or severely damaged skin.
• Not suitable for individuals with a history of sensitivity or reaction to any of the cream's components.
• Should not be used in the eyes or on mucous membranes.
• Contraindicated in individuals with a history of kidney disease or kidney failure.
• Do not use if you have a skin condition called Exfoliative Dermatitis.
• Avoid using on skin areas with eczema or severe inflammation.

The side effects of Clioquinol Cream may include:

• Skin irritation or redness at the application site
• Burning or stinging sensation
• Itching or rash
• Dryness of the skin
• Peeling or scaling of the skin
• Swelling or inflammation
• Allergic reactions, such as hives or difficulty breathing (rare)
• Prolonged use may lead to skin discoloration or increased sensitivity to sunlight.

Following are the precautions and warnings:

• Clioquinol Cream is for external use only and should be applied strictly as directed by a healthcare professional. Avoid applying it to the eyes, mouth, or open wounds.
• It is not recommended for individuals with a known sensitivity or allergy to clioquinol or any other ingredients in the cream. Discontinue use if any signs of allergy or skin irritation occur.
• This medication should be used with caution in children and the elderly, as they may be more sensitive to its effects.
• Avoid excessive usage and prolonged treatment without medical supervision. Prolonged use may result in increased absorption and potential systemic effects.
• Clioquinol Cream should not be used on large areas of the body or under occlusive dressings, as this may increase the risk of systemic absorption.
• Wash your hands thoroughly after applying the cream to avoid accidental transfer to other areas of the body or to the eyes.
• If symptoms persist or worsen, or if new symptoms appear, consult a doctor immediately.
• Keep out of reach of children and pets. Store it in a cool, dry place, away from direct sunlight and heat.

Following are the drug interactions for Clioquinol Cream:

• Clioquinol may interact with oral anticoagulants, increasing the risk of bleeding. Regular monitoring of prothrombin time is recommended.
• Concomitant use with corticosteroids can lead to increased skin atrophy and reduced wound healing.
• Avoid using other topical medications at the same time without medical advice, as it may increase skin irritation.
• The effect of Clioquinol can be reduced by certain antiseptics, like hydrogen peroxide.
• Combining with other drugs that affect kidney function may increase the risk of kidney-related side effects.
• Topical use of Clioquinol with other medications containing similar active ingredients should be avoided to prevent excessive exposure.
• Clioquinol may interact with oral antidiabetic drugs, requiring close monitoring of blood glucose levels.

Following are the food interactions to consider with Clioquinol Cream:

• Clioquinol Cream should not be applied to areas with open wounds or broken skin to avoid potential irritation and increased absorption of the medication.
• Avoid consuming grapefruit or grapefruit juice as it may interfere with the metabolism of certain medications, although this interaction is less likely with topical applications.
• Alcohol may not directly interact with Clioquinol Cream, but it can impair your judgment and increase the risk of skin injuries, especially if you need to apply the cream to hard-to-reach areas.
• Fatty foods have no direct impact on the effectiveness of Clioquinol Cream, but maintaining a healthy diet supports overall skin health.
• Spicy foods may cause skin flushing or discomfort, especially if the treated area is sensitive or irritated.
• Dairy products do not interfere with the topical application of Clioquinol Cream.
• Sugary foods and beverages are generally safe, but maintaining a balanced diet is advisable for overall health.
• Caffeinated beverages do not have a significant interaction with Clioquinol Cream, but staying hydrated is essential for skin health.

Clioquinol Cream should be stored in a secure and controlled environment, preferably in a cool and dry place at room temperature (below 25°C/77°F). Protect the cream from direct exposure to sunlight, heat, and moisture, as these conditions can degrade its quality. Keep the cream in its original container, tightly sealed, to maintain its integrity and prevent contamination. When disposing of unused or expired Clioquinol Cream, do not flush it down the toilet or pour it into any water sources. Contact your pharmacist or healthcare provider for guidance on proper disposal methods to ensure it is handled in an environmentally safe manner. Always keep medications out of the sight and reach of children to prevent accidental exposure or ingestion.

Following are the quick tips for Clioquinol Cream:

• Wash your hands thoroughly before and after applying the cream to ensure hygiene.
• Clean and dry the affected area before applying the cream for better absorption.
• Apply a thin layer of the cream to the affected area as directed by your healthcare provider.
• Gently rub the cream into the skin until it is completely absorbed.
• Avoid applying the cream on broken or irritated skin.
• Do not cover the treated area with bandages or tight clothing to allow the skin to breathe.
• Store the cream at room temperature, away from direct sunlight and moisture.