Clioquinol-Hydrocortisone 5g Cream

Hydrocortisone, the active corticosteroid in the cream, works by reducing inflammation and suppressing immune responses in the skin. It binds to corticosteroid receptors within cells, leading to changes in gene expression that result in anti-inflammatory effects. Specifically, hydrocortisone inhibits the production and release of pro-inflammatory mediators, reduces capillary permeability, and stabilizes cell membranes. Clioquinol, the other component, is an antifungal and antibacterial agent that disrupts microbial cell membranes, interfering with essential microbial functions and inhibiting the growth of fungi and bacteria. This dual action makes the cream effective in treating various skin conditions where both inflammation and microbial infections are present.

Hydrocortisone, Clioquinol

Corticosteroid-Antifungal Combination

Cream

The following are the uses of Hydrocortisone, Clioquinol Cream:

• Used for treating inflammatory skin conditions like eczema, psoriasis, and dermatitis.
• Used for relieving itching, redness, and inflammation.
• Used for managing skin infections caused by bacteria or fungi.
• Used for reducing skin discoloration and hyperpigmentation.
• Used for accelerating the healing of minor cuts, scrapes, and burns.
• Used for soothing skin irritation after insect bites or stings.
• Used for preventing and treating skin reactions to certain medications.
• Used for providing temporary relief from various skin rashes.

In the case of an overdose of Hydrocortisone and Clioquinol Cream, it is important to act promptly. Wash the affected area thoroughly with water to remove any excess cream. If ingested, contact a healthcare professional immediately for guidance. Overapplication may lead to temporary skin irritation, but severe reactions are rare. Timely intervention can help manage any potential side effects effectively.

In the case of a missed dose of Hydrocortisone, apply the cream as soon as you remember. However, if it's almost time for your next dose, skip the missed application and continue with your regular schedule. For Clioquinol Cream, if you forget to apply it, apply it as soon as you remember, but avoid applying extra to make up for the missed dose. It's important not to double the dose to catch up, as this may increase the risk of side effects.

To apply Hydrocortisone, Clioquinol Cream, clean and dry the affected skin area, then apply a thin layer of the cream to the skin, gently rubbing it in as directed by your healthcare provider, typically twice a day or as instructed.

Following are the conditions/situations to avoid when using Hydrocortisone, Clioquinol Cream:

• Do not use if you have a known allergy or sensitivity to Hydrocortisone or Clioquinol.
• Avoid using on broken or infected skin.
• Not suitable for individuals with tuberculosis of the skin.
• Do not use on skin conditions caused by vaccinations, or viral infections such as chickenpox or shingles.
• Contraindicated for individuals with fungal, bacterial or viral skin infections, unless appropriate anti-infective therapy is also used.
• Avoid using on skin areas with acne, rosacea, or perioral dermatitis.
• Do not use near the eyes, mouth, or other mucous membranes.
• Not recommended for long-term use, especially on large areas of the skin.
• Should not be used in individuals with a history of hypersensitivity or allergic reactions to any of the cream's components.
• Do not use on children under 2 years of age without medical advice.

The side effects of Hydrocortisone, Clioquinol Cream may include:

• Skin irritation or redness at the application site
• Burning or stinging sensation
• Itching
• Dryness or peeling of the skin
• Thinning of the skin (with prolonged use)
• Allergic reactions (such as rash, swelling, or difficulty breathing)
• Secondary infections, especially with long-term use
• Skin discoloration or hyperpigmentation

Following are the precautions and warnings for Hydrocortisone, Clioquinol Cream:

• Avoid contact with eyes and mucous membranes. In case of accidental contact, rinse thoroughly with water.
• This cream is for external use only and should not be ingested or used on open wounds or broken skin.
• Do not use this medication for extended periods without consulting a healthcare professional, as prolonged use may lead to skin thinning and other adverse effects.
• If you have a known allergy to hydrocortisone, clioquinol, or any other ingredients in the cream, do not use it.
• Keep out of reach of children. If accidental ingestion occurs, seek immediate medical attention.
• Wash your hands before and after applying the cream to avoid spreading the infection to other areas or individuals.
• Do not bandage or wrap the treated area tightly, as this may increase the absorption of the medication and potentially cause adverse effects.

Following are the drug interactions for Hydrocortisone, Clioquinol Cream:

• Topical corticosteroids like hydrocortisone may increase the absorption of other drugs applied to the skin, such as other topical medications or even systemic medications with local application.
• Clioquinol may interact with other medications metabolized by the liver, potentially affecting their metabolism and increasing the risk of side effects.
• Hydrocortisone can reduce the effectiveness of medications used to treat skin infections, such as antifungals or antibiotics.
• Combining with other topical medications, such as retinoids or benzoyl peroxide, may increase skin irritation.
• Use with other corticosteroid medications may increase the risk of systemic absorption and potential side effects.
• Drugs that induce or inhibit liver enzymes, such as rifampicin or ketoconazole, may alter the effects of clioquinol.
• It is advised to avoid using other medications with similar actions, such as other antiparasitic or antifungal agents, without medical advice.

Following are the food interactions to be aware of when using Hydrocortisone, Clioquinol Cream:

• Avoid consuming excessive amounts of salt or high-sodium foods, as Hydrocortisone can cause sodium retention, leading to fluid retention and increased blood pressure.
• Limit or avoid caffeine intake from coffee, tea, or energy drinks, as it may exacerbate nervousness, tremors, or sleep disturbances.
• Consuming potassium-rich foods like bananas, oranges, and spinach is beneficial since Hydrocortisone can cause potassium loss.
• Avoid grapefruit and grapefruit juice, as they may affect the metabolism of Hydrocortisone, altering its effectiveness.
• Alcohol may increase the risk of gastrointestinal issues, so it's best to limit or avoid it during treatment.
• Dairy products, such as milk and yogurt, may interact with Clioquinol, potentially reducing its absorption. Consider separating these foods from medication timing.
• Avoid spicy foods, as they can irritate the skin and exacerbate any skin-related side effects.
• Stay well-hydrated by drinking plenty of water to support overall skin health during treatment.

Hydrocortisone, Clioquinol Cream should be stored in a cool and dry place, preferably at room temperature (68°F to 77°F). Keep the cream in its original container, tightly sealed, to maintain its integrity and prevent contamination. Avoid exposing the cream to direct sunlight, heat, or moisture, as this can impact its effectiveness. Always check the expiration date before use, and properly dispose of any expired or unused cream. Do not pour it down the drain or flush it; instead, follow local guidelines for pharmaceutical waste disposal or consult a healthcare professional for guidance on safe disposal methods. Keep the cream out of children's reach to prevent accidental contact or ingestion.

Following are the quick tips for Hydrocortisone, Clioquinol Cream:

• Apply a thin layer to the affected area as directed by your doctor.
• Wash and dry the affected area before application.
• Use the cream as prescribed, not more than directed.
• Wash your hands after applying, unless it's used for treating the hands.
• Avoid contact with eyes, nose, and mouth.
• Inform your doctor if your condition doesn't improve or worsens.
• Store the cream at room temperature, away from light and moisture.