Co-Renitec (10/25mg) 20 Tablets

Co-Renitec (10/25mg) 20 Tablets

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  • Manufacturer OBS Pakistan (Pvt.) Ltd.
  • Generic Name Hydrochlorothiazide, Enalapril

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Storage/Disposal
  • Description

    Enalapril Maleate serves as an angiotensin-converting enzyme (ACE) inhibitor. Its role is to reduce the production of angiotensin II, a hormone that constricts blood vessels, thereby contributing to elevated blood pressure. By curbing the breakdown of bradykinin, enalapril promotes relaxed blood vessels, leading to better blood flow and lower blood pressure. Hydrochlorothiazide, on the other hand, is a thiazide diuretic commonly referred to as a "water pill." Its purpose is to remove excess fluid from your body. It achieves this by stopping the reabsorption of sodium (salt) and chloride ions in the distal renal tubule, which results in increased urine production. This diuresis helps alleviate congestion in the blood vessels, thereby reducing blood pressure. Using these two drugs in conjunction provides a complementary effect to mitigate high blood pressure by relaxing blood vessels and eliminating excess fluid. This reduces the overall workload of the heart and improves blood circulation.

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  • Ingredients

    Hydrochlorothiazide, Enalapril
  • Drug Class

    Diuretic, ACE Inhibitor

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  • Dosage Form

    Tablet

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  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Lower blood pressure
    • Treat hypertensions
    • Prevent strokes
    • Reduce risk of heart attack
    • Protect kidneys
    • Manage heart failure

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  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Hypertension- Take 1 tablet daily, may increase as directed by a healthcare provider.
    • Heart Failure- Take 1 tablet daily, may be adjusted based on response and tolerance.
    • Edema- Take 1 tablet daily, may increase as needed based on fluid retention.

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  • In case of Overdose

    An Enalapril Maleate 10mg and Hydrochlorothiazide 25mg overdose can be treated with medications that counteract the effects of these drugs, such as charcoal to absorb them in the digestive system. These drugs are used to treat hypertension, so treatment for an overdose may involve treating any low blood pressure or elevated potassium levels. Intravenous fluids may be administered if blood pressure is low, and if the patient is experiencing acute kidney injury, dialysis may be necessary. In the case of an overdose, the first step is to contact 911 or local emergency services. It's important to note that overdose treatment should be carried out under the supervision of a medical professional.

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  • Missed Dose

    If you have missed a dose of your medication, there is no need to panic. The first step is to take it as soon as possible. If it is almost time for your next scheduled dose, it is best to skip the missed dose and resume your regular schedule. This is to avoid doubling up on doses, which could be harmful. If you are uncertain about whether to take a missed dose, or how to take your medication in general, it is recommended that you consult with your doctor or pharmacist to ensure you are following the correct procedure. It is crucial to take this medication as directed and at the scheduled times to maintain its effectiveness and avoid any unwanted side effects.

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  • How To Use

    Enalapril Maleate 10mg, Hydrochlorothiazide 25mg is a medication that is typically taken once daily. The exact directions for taking this medication depend on several factors. These factors include the severity of the condition being treated, other medications being taken, and individual patient factors. It is important to follow the instructions provided by your doctor or the medication label. Before starting this medication, read the medication guide provided by the pharmacist. If you have questions, ask your doctor or pharmacist. Take this medication by mouth, usually once daily, with or without food. It is important to take it at the same time each day to keep the level of the medication in your blood even. Drink plenty of water while taking this medication to help prevent dehydration and kidney problems. Stopping this medication suddenly may worsen your condition, so do not stop taking it without consulting your doctor. It is important to monitor your blood pressure regularly and follow up with your doctor as scheduled; your doctor may adjust the dosage based on your blood pressure results. This medication may interact with other drugs, so it is important to tell your doctor about all the medications you are taking. Severe side effects such as low blood pressure, abnormal heart rhythms, and kidney problems require immediate medical attention; if you experience these side effects, stop taking the medication and seek medical attention. Consult with your doctor for specific directions based on your condition. It is also important to inform your doctor about all other medications you are taking, including over-the-counter medicines, vitamins, and herbal supplements.

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  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • If you are allergic to Enalapril Maleate or Hydrochlorothiazide, or any of the other ingredients in this medication.
    • If you have ever had an allergic reaction to similar medications in the past.
    • If you have diabetes or kidney problems, or sometimes, heart problems. Enalapril may be used in these instances, however, Hydrochlorothiazide is typically avoided due to its potential to cause further kidney damage and elevate blood sugar levels.

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  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Dizziness
    • Lightheadedness
    • Fatigue
    • Vertigo
    • Nausea
    • Diarrhea
    • Constipation
    • Dry cough
    • Impaired cognition
    • Decreased libido
    • Erectile dysfunction
    • Orthostatic hypotension
    • Hypotension (low blood pressure)
    • Acute angle-closure glaucoma
    • Swelling of the hands, ankles, or feet
    • Rash
    • Itchiness
    • Urticaria
    • Photosensitivity
    • Sore throat
    • Stuffy nose
    • Acute pulmonary edema
    • Musculoskeletal pain
    • Back pain
    • Weakness
    • General discomfort
    • Headache
    • Apprehension
    • Anxiety
    • Confusion
    • Depressed mood
    • Drowsiness
    • Sleep disturbance
    • Somnolence
    • Agitation
    • Restlessness
    • Irritability
    • Mood swings
    • Impaired coordination
    • Impaired judgment
    • Indecisiveness
    • Dulled sensation
    • Decreased sexual function
    • Dry eyes
    • Blurred vision
    • Eye pain
    • Seeing halos around lights
    • Light sensitivity
    • Blindness
    • Double vision
    • Headache
    • Vertigo
    • Nausea
    • Nausea
    • Vomiting
    • Diarrhea
    • Constipation
    • Itchiness
    • Rash
    • Urticaria
    • Photosensitivity
    • Throat soreness
    • Stuffy nose

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  • Precautions & Warnings

    Before using Co Renitec, it is important to be mindful of the following precautions and warnings:

    • Do not use Co Renitec if you have a low amount of sodium in your blood.
    • If you are allergic to Co Renitec, inform your doctor before using it.
    • Share the list of all products you are using, including allopathic and herbal remedies, with your doctor before starting Co Renitec.
    • Consult your doctor before using Co Renitec if you are pregnant or breastfeeding.
    • Do not use Co Renitec without consulting your doctor if you have liver or renal issues.

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  • Drug Interactions

    Drug interactions with Hydrochlorothiazide, Enalapril combination include:

    • Other antihypertensives (e.g., beta-blockers, calcium channel blockers) (additive effects on blood pressure)
    • Potassium-sparing diuretics (e.g., spironolactone) (risk of hyperkalemia)
    • Lithium (risk of altered lithium levels)
    • NSAIDs (e.g., ibuprofen) (reduced effectiveness of antihypertensives)
    • ACE inhibitors (e.g., enalapril) (additive effects on blood pressure and renal function)
    • Antidiabetic agents (e.g., metformin) (possible impact on blood glucose control)

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  • Storage/Disposal

    Store hydrochlorothiazide and enalapril at room temperature, away from moisture, heat, and direct light. Keep the medications in their original packaging, tightly closed, and out of reach of children and pets. Avoid storing them in the bathroom or areas with high humidity. For maximum effectiveness, ensure that the medications are kept in a cool, dry place. If you have any expired or unused medication, consult local disposal guidelines or a drug take-back program for safe disposal.

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