Co-Valid (80/12.5mg) 28 Tablets

Valsartan 80mg and Hydrochlorothiazide 12.5mg is a combination medication used to treat high blood pressure, reducing blood pressure by inhibiting the renin-angiotensin-aldosterone system (RAAS) and reducing fluid retention. Valsartan, a selective competitive angiotensin II receptor type 1 (AT1) antagonist, blocks the binding of angiotensin II to the AT1 receptor, leading to decreased vascular contractility and cardiac venous return. Its actions on angiotensin II receptors directly involve vascular smooth muscle contraction and tubular sodium reabsorption in the kidney. Hydrochlorothiazide, a thiazide diuretic, enhances sodium and water excretion, reducing blood volume and arterial pressure by interfering with sodium reabsorption in the distal renal tubule, primarily via inhibition of sodium-chloride symporters (NCISTS) in the luminal membrane of renal proximal tubule cells. This medication is effective for treating hypertension, starting at a lower dose and your doctor may adjust it depending on your response to the treatment and blood pressure goals. It is important to follow your doctor's instructions for taking this medication precisely and completing the full course as prescribed, as this information is meant to supplement, not substitute for, any advice or information from your veterinarian or veterinary surgeon and is not intended to diagnose, treat, or cure.

Hydrochlorothiazide 12.5mg, Valsartan 80mg

Valsartan:

Tablet

Hydrochlorothiazide, Valsartan combination is utilized for the following therapeutic indications:

• Treating hypertension (high blood pressure)
• Reducing the risk of cardiovascular events
• Providing synergistic effects for better blood pressure control
• Enhancing renal protection in patients with hypertension

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For Valsartan 80mg-
• Heart failure – 5mg to 160mg per day in a single dose
• High blood pressure – 80mg to 320mg per day in a single dose
• Treat complications after a heart attack – 80mg to 320mg per day in a single dose
• For Hydrochlorothiazide 12.5mg-
• Heart failure – 12.5mg to 50mg per day in a single dose
• High blood pressure – 12.5mg to 50mg per day in a single dose

If an overdose of Valsartan 80mg and Hydrochlorothiazide 12.5mg is exhibited, it is vital to seek medical attention immediately. Treatment for the overdose will vary depending on the symptoms the patient is experiencing and how severe the overdose is. In order to ensure the patient's safety, they will require treatment under the supervision of medical professionals, which may include vasopressors and dialysis.

It is important to take your blood pressure medication as directed to maintain control over your blood pressure. If you miss a dose of Valsartan 80mg and Hydrochlorothiazide 12.5mg, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is advised to skip the missed dose and maintain your regular dosing schedule to avoid a potential overdose. It is always best to consult a medical professional, such as your doctor or pharmacist, for guidance on how to manage missed doses appropriately, as there may be specific circumstances or health factors that need to be considered based on your personal medication and medical history. They can provide you with the most accurate and up-to-date information to ensure that you handle missed doses safely and effectively.

Valsartan 80mg is typically prescribed anywhere from 80-320mg daily, depending on an individual's response and blood pressure goals. It is usually taken once or twice a day and should be taken with or without food. Valsartan works best when taken as prescribed and it is important to have close monitoring by a physician to ensure the dosage is appropriate to achieve target goals. It is vital to consult a doctor before stopping use of Valsartan as discontinuation may result in adverse effects on blood pressure and possible progression of underlying heart problems. Hydrochlorothiazide 12.5mg is typically prescribed anywhere from 12.5-25mg daily depending on the patient's needs. This medication should be taken at the same time every day with a glass of water and with or without food to experience consistent blood pressure control. Hydrochlorothiazide may cause excessive urination and the chance of dehydration, so it is important to increase water intake while taking this medication. Precautions and specific directions were provided to you by your doctor on the basis of your individual medical history. Overall, it is important to be aware of any side effects that you may experience while taking these medications and report any concerns to your healthcare provider.

Discerning instances where this medication may not be appropriate:

• It is crucial that you speak to a medical professional about your personal circumstances and they will provide you with guidance on your individual situation.

Unraveling the side effects lurking behind this medications are as follows:

• Dizziness
• Lightheadedness
• Low blood pressure
• High potassium levels
• Kidney failure
• Dry mouth
• Increased urination
• Fatigue
• Muscle weakness
• Diarrhea
• Nausea
• Vomiting
• Stomach pain
• Constipation
• Headache
• Ringing in the ears
• Shortness of breath
• Chest pain or discomfort
• Joint pain
• Back pain
• Leg pain
• Ankle swelling
• Intestinal irritation
• Mood changes
• Impaired coordination
• Impaired thinking or concentration
• Suicidal thoughts or behaviors
• Bladder cancer
• Breast cancer
• Lung cancer
• Kidney cancer
• Stroke
• Heart failure
• Impaired vision
• Memory impairment
• Confusion
• High potassium levels in the blood
• Low sodium levels in the blood
• Elevated levels of creatinine in the blood

Valsartan is a medication used to treat high blood pressure and heart problems. It functions by blocking the hormone that tightens blood vessels, allowing the blood to flow more smoothly and enabling the heart to pump more efficiently. On the other hand, Hydrochlorothiazide is a medication utilized to treat swelling and fluid buildup caused by conditions like heart failure, liver disease, and kidney disease. It is a potent diuretic that removes excess water and salt from the body, thereby reducing body fluid amount and lowering blood pressure. To properly store these medications, it is crucial to adhere to the following steps. First, keeping them in their original container helps prevent confusion with other medications. Second, they should be stored at room temperature between 59°F and 86°F (15°C and 30°C), and it is best to avoid humid areas like a bathroom closet to prevent moisture accumulation inside the container. Third, these medications should be kept away from direct heat and sunlight. Additionally, it is advised to avoid freezing them as it can alter their chemical composition and render them ineffective. Finally, these medications should be kept out of the reach of children and pets, preferably in a locked cabinet or drawer. When traveling, it is important to store them in a cool, dry place in their original container, such as a backpack or purse. To ensure utmost safety, always maintain the medications' separation from those of others to prevent mixing them up. Should you have further queries or concerns about storing these specific medications, it is advised to seek professional medical advice or consult a pharmacist for more in-depth information.