Co-Valtec (160/25mg) 28 Tablets

Valsartan works by blocking the binding of angiotensin II to the AT1 receptor, which inhibits the adverse cardiovascular effects of angiotensin II, such as vasoconstriction, increased aldosterone secretion, and cardiac hypertrophy. By preventing these effects, valsartan promotes vasodilation, reduces aldosterone secretion, helps the heart pump more efficiently, and decreases blood pressure. Hydrochlorothiazide, on the other hand, works by inhibiting the sodium-chloride symporter in the distal convoluted renal tubule, which leads to increased excretion of sodium and chloride ions and reduced reabsorption of water. This increases urine volume and decreases blood pressure by reducing the venous return of blood to the heart. It also increases potassium excretion. Used together, these two medications work in complementary ways to help treat hypertension, lowering both diastolic and systolic blood pressure. They can also be used to treat edema and hyperglycemia in patients with hypertension.

Arb/Diuretic/Angiotensin Ii Receptor Blocker

Unveiling its multifaceted uses and transformative applications as follows:

• Treat high blood pressure (hypertension)
• Protect the kidneys in people with diabetes mellitus
• Lower the risk of developing complications such as heart attacks and stroke

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Valsartan 160mg-
• High blood pressure (hypertension)• Usual starting dose is 160mg once a day. Maximum dose is 640mg per day.
• Congestive heart failure (CHF)• Start at 80mg and may increase to 320mg depending on tolerance. Often given in combination with other drugs.
• Treatment of strokes and aortic stenosis• Same as hypertension dosage
• Hydrochlorothiazide 25mg-
• High blood pressure (hypertension)• Initial dose of 25mg once a day. May increase to 50mg per day.
• Congestive heart failure (CHF)• Used in combination with Valsartan or with other drugs.
• renal disease• Used in combination with other drugs.

An overdose of Valsartan 160mg and Hydrochlorothiazide 25mg can be serious, and medical attention should be sought immediately if an overdose is suspected. Do not attempt to induce vomiting or self-medicate without first consulting a medical professional as this may prove harmful.

It is important to take your medication as directed to ensure optimal results. If you miss a dose, it is recommended that you take it as soon as possible unless it is almost time for your next scheduled dose. It's crucial to follow the instructions provided by your physician or the prescription label carefully. Ensure you don't take an extra dose to make up for the missed one, as this can lead to an overdose. If you have any questions or concerns about missing a dose, it's best to consult with your physician or pharmacist for guidance specific to your situation.

Valsartan 160mg and Hydrochlorothiazide 25mg are medications used to treat high blood pressure. These drugs are taken orally, with or without food, as directed by a physician. It is essential to adhere to the prescribed dosage and timing to ensure the medication's effectiveness. The recommended starting dose of Valsartan 160mg is 160mg once daily, which may be increased to a target maintenance dose of 320mg once daily after one to two weeks, depending on the control of blood pressure and tolerability. For Hydrochlorothiazide 25mg, the recommended starting dose is 25mg once or twice daily, which may be increased every one to two weeks to a maximum of 50mg once or divided into two doses per day. Before stopping this medication or making any changes to the prescribed dosage, it is important to consult a physician or healthcare provider, as it may be necessary as part of an overall treatment plan to maintain healthy blood pressure levels. For any questions or concerns regarding specific dosage and instructions, one should consult their physician or pharmacist.

Discerning instances where this medication may not be appropriate:

• People who are anuric, hypersensitive to the components of this combination, or have severe hypotension, hypovolaemia, uncontrolled hyperkalemia, or Valentine's syndrome should not take this combination.
• This combination can interact with other medications, such as lithium, potassium-sparing diuretics, potassium supplements, NSAIDs, and salt substitutes containing potassium.
• As always, consult your physician before taking any medication and do not stop or change the schedule of any therapy without your doctor's approval.

Unraveling the side effects lurking behind this medications are as follows:

• Dizziness
• Lightheadedness
• Low blood pressure
• High blood potassium
• Kidney problems
• Weakness
• Fluid retention
• Dehydration
• Dry mouth
• Constipation
• Increased urination
• Fatigue
• Malaise
• Muscle cramps
• Gastric irritation
• Nausea
• Vomiting
• Diarrhea
• Erectile dysfunction
• Mood swings
• Anxiety
• Insomnia
• Drowsiness
• Irritability
• Confusion
• Loss of appetite
• Weight loss
• Bronchospasm
• Throat irritation
• Cough
• Shortness of breath
• Asthma
• Back pain
• Muscle pain
• Joint pain
• Rash
• Hyperglycemia
• Decreased glucose tolerance
• Elevated LDL cholesterol
• Elevated triglycerides
• Hematuria
• Vaginal itching
• Vaginal discharge
• Impaired sexual function
• Premature ejaculation
• Sexual dysfunction
• Dry eyes
• Eye irritation
• Blepharitis
• Cataract
• Corneal opacity
• Iridial infection
• Lens disorder
• Retinal disorder
• Vitreous detachment
• Visual field defect
• Myocardial infarction
• Pulmonary fibrosis
• Interstitial lung disease
• Liver enzyme abnormalities
• Liver failure
• Hepatitis
• Kidney failure

Valsartan (160mg) and hydrochlorothiazide (25mg) is a combination medication used to treat hypertension (high blood pressure). It is essential to follow the directions of your healthcare provider regarding the proper use and dosage of the medication for optimal results. Here's how you can store this medication: