Cofcol 250 Tablets

Dextromethorphan, often referred to as DXM, exerts its primary mechanism of action as an antitussive (cough suppressant) by acting upon sigma-1 and sigma-2 receptors in the central nervous system. This interaction inhibits the brain's urge to cough, effectively suppressing the cough reflex. Specifically, dextromethorphan binds to these sigma receptors, which are located in various regions of the brain, including the brainstem and spinal cord, leading to a reduction in the sensitivity of cough reflex pathways. This mechanism allows dextromethorphan to provide relief from coughing without directly affecting the lungs or airways, making it a popular choice in over-the-counter cough medications.

dextromethorphan

Antitussive

Tablet

The following are the uses of dextromethorphan Tablet:

• Used for suppressing coughs, especially non-productive coughs caused by the common cold or other respiratory infections.
• Used for providing temporary relief from cough symptoms to allow better sleep and rest.
• Used for treating symptoms associated with allergies, such as itchy throat and cough.
• Used for reducing the urge to cough in conditions like bronchitis and asthma.
• Used for managing cough in patients with chronic obstructive pulmonary disease (COPD).
• Used for alleviating cough discomfort after minor throat or mouth surgery.
• Used for cough control in situations where coughing needs to be minimized, such as during public speaking or singing.

Take as per doctor's prescription

In the case of an overdose of dextromethorphan tablets, individuals may experience a range of symptoms including nausea, vomiting, dizziness, and in severe cases, hallucinations and seizures. It is important to recognize that overdosing on this medication can lead to serious health complications. Immediate actions should be taken, such as contacting a healthcare professional or poison control center, who can provide guidance on the necessary steps to address the overdose and ensure the individual's safety and well-being.

In the case of a missed dose of dextromethorphan tablets, it is generally advised to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication. It is important to follow the prescribed dosage instructions for optimal effectiveness and to minimize potential adverse reactions.

To take dextromethorphan tablets, swallow the prescribed number of tablets with a glass of water, following the dosage instructions provided by your healthcare professional, and ensure you take the medication as directed without missing any doses for optimal effectiveness.

Here are the situations or conditions when dextromethorphan tablets should not be taken:

• Do not take if you have a known allergy or hypersensitivity to dextromethorphan or any of the excipients in the tablet formulation.
• Avoid using in patients with a history of asthma or other chronic respiratory conditions, as it may worsen breathing.
• Not suitable for individuals with liver or kidney disease, as it may affect drug metabolism and elimination.
• Contraindicated in patients with a history of seizures or conditions that lower the seizure threshold.
• Do not use in patients who are taking monoamine oxidase inhibitors (MAOIs) or have taken them within the last 14 days.
• Avoid in individuals with gastrointestinal disorders, as it may affect drug absorption.
• Not recommended for patients with a history of gastrointestinal bleeding or ulcers.
• Should not be used in children under 4 years of age due to the risk of respiratory depression.
• Contraindicated in individuals with a history of head injury or increased intracranial pressure.
• Avoid using dextromethorphan tablets if you have a condition that affects your consciousness or ability to swallow.

The side effects of dextromethorphan Tablet may include:

• Drowsiness or sedation
• Confusion or disorientation
• Nausea and vomiting
• Constipation or stomach pain
• Dry mouth
• Dizziness
• Blurred vision
• Allergic reactions (such as rash, itching, or swelling)

Following are the precautions and warnings for dextromethorphan Tablets:

• Not suitable for individuals with a known allergy to dextromethorphan or any of the tablet's components.
• Avoid in patients with a history of liver disease, as it may worsen liver function.
• Exercise caution when taking dextromethorphan with other medications, especially those that affect the central nervous system, to avoid potential drug interactions.
• Do not consume alcohol while taking these tablets, as it may increase the risk of side effects.
• Patients with a history of gastrointestinal issues should use with caution, as it may cause stomach upset.
• Not recommended for children under 12 years of age unless prescribed by a healthcare professional.
• Consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking this medication.

Following are the drug interactions for Dextromethorphan Tablets:

• Alcohol and other CNS depressants (e.g., benzodiazepines, opioids) may increase the sedative effects of dextromethorphan, leading to enhanced drowsiness and impaired coordination.
• Monoamine oxidase inhibitors (MAOIs) should be avoided with dextromethorphan due to the risk of serotonin syndrome, a potentially dangerous condition.
• Dextromethorphan can interact with other cough and cold medications containing similar active ingredients, leading to potential overdose.
• Certain antidepressants (e.g., SSRIs, tricyclic antidepressants) may increase dextromethorphan's effects and side effects, including drowsiness and dizziness.
• Anticonvulsants like phenytoin may reduce the effectiveness of dextromethorphan, requiring dosage adjustments.
• Dextromethorphan may increase the risk of side effects when taken with medications metabolized by the liver, such as certain antibiotics and antifungal drugs.
• It may also affect the metabolism of other drugs, including some antiarrhythmic medications and beta-blockers, requiring close monitoring.

Following are the food interactions for Dextromethorphan Tablet:

• Grapefruit juice can interfere with the metabolism of dextromethorphan, leading to increased drug levels in the body and potentially causing adverse effects. It's best to avoid grapefruit and grapefruit products while taking this medication.
• Alcohol consumption is not recommended as it may enhance the sedative effects of dextromethorphan, leading to increased drowsiness and impaired coordination.
• Avoid high-fat meals as they may delay the absorption of dextromethorphan, potentially reducing its effectiveness.
• Caffeine-containing beverages like coffee and energy drinks may reduce the sedative effects of dextromethorphan, making it less effective for cough suppression.
• Chocolate, especially dark chocolate, contains a compound called theobromine, which can stimulate the nervous system and counteract the sedative properties of dextromethorphan.
• Avoid spicy foods as they can irritate the throat and exacerbate coughing, reducing the effectiveness of dextromethorphan.
• Dairy products may increase mucus production and throat congestion, making it more difficult for dextromethorphan to alleviate cough symptoms.
• It's advisable to maintain a balanced diet and stay well-hydrated to support overall health and aid in the recovery process while taking dextromethorphan.

Dextromethorphan tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. Avoid storing the tablets in bathrooms or areas exposed to heat, as temperature fluctuations can impact their effectiveness. Proper disposal is crucial; do not flush or pour them down the drain. Consult a pharmacist or healthcare professional for safe disposal methods, and always keep the medication away from children to prevent accidental consumption. Regularly check the expiration date, and dispose of any expired or unused tablets accordingly.

Yes

Here are the quick tips for Dextromethorphan Tablet:

• Take the tablet as directed by your doctor, ensuring you follow the prescribed dosage and duration.
• Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
• Maintain a consistent dosing schedule by taking the tablet at the same time(s) each day.
• Dextromethorphan may cause drowsiness; avoid driving or operating machinery until you know how it affects you.
• Avoid alcohol consumption while taking this medication, as it may intensify side effects.
• Inform your doctor about all medications you are currently taking to prevent potential drug interactions.
• Store the tablets at room temperature, away from moisture and direct sunlight.