Coldex Tablets

Cetirizine, a second-generation antihistamine, primarily exerts its effect by competitively binding to histamine H1 receptors, thereby blocking the action of histamine. This mechanism helps to alleviate allergic symptoms and reduce itching. Paracetamol, an analgesic and antipyretic, acts by inhibiting the synthesis of prostaglandins, which are involved in pain and inflammation signaling. It primarily targets cyclooxygenase (COX) enzymes in the central nervous system, reducing the perception of pain and lowering fever. Phenylephrine hydrochloride, a sympathomimetic amine, stimulates alpha-adrenergic receptors, causing vasoconstriction of the blood vessels in the nasal passages. This action leads to reduced congestion and facilitates easier breathing by shrinking swollen nasal tissues.

Cetirizine, Paracetamol, Phenylephrine Hydrochloride

Antihistamine, Analgesic, Decongestant.

Tablet

The following are the uses of Cetirizine, Paracetamol, Phenylephrine Hydrochloride Tablet:

• Used for relieving symptoms of allergies such as hay fever, dust allergies, pet allergies, and skin reactions.
• Used for reducing fever and providing pain relief for mild to moderate aches and pains.
• Used for relieving congestion and sinus pressure by shrinking swollen blood vessels in the nose and sinuses.
• Used for treating symptoms of the common cold, including runny nose, sneezing, and congestion.
• Used for alleviating headaches and sinus headaches.
• Used for providing temporary relief from itchy, watery eyes caused by allergies.
• Used for promoting overall comfort and well-being during allergy seasons or when experiencing mild to moderate pain.

In the case of an overdose of Cetirizine, Paracetamol, and Phenylephrine Hydrochloride Tablet, individuals may experience an array of symptoms. These can include drowsiness, nausea, and confusion, with more severe cases leading to rapid heartbeat, dizziness, and even seizures. Promptly seek medical advice if you suspect an overdose, as early intervention is vital to mitigate potential health risks and ensure appropriate treatment. It is crucial to remain calm and provide accurate information to healthcare professionals to facilitate effective management of the situation.

In the case of a missed dose of Cetirizine, Paracetamol, and Phenylephrine Hydrochloride Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare provider for guidance on how to safely resume your medication regimen.

To take the Cetirizine, Paracetamol, and Phenylephrine Hydrochloride Tablet, swallow the tablet whole with a glass of water, following the dosage instructions provided by your healthcare professional; typically, this medication is taken once or twice daily as directed, and it can be taken with or without food, ensuring you adhere to the prescribed frequency and duration of treatment.

Here are the conditions or situations when Cetirizine, Paracetamol, Phenylephrine Hydrochloride Tablet should not be used:

• Not recommended for individuals with a known allergy to any of the components, including Cetirizine, Paracetamol, or Phenylephrine Hydrochloride.
• Avoid in patients with severe kidney or liver impairment.
• Should not be used in individuals with high blood pressure that is not controlled.
• Contraindicated in patients with narrow-angle glaucoma.
• Not suitable for individuals with severe heart-related problems.
• Should be avoided in patients with a history of stomach or intestinal obstruction.
• Do not use if you have an overactive thyroid without consulting a doctor.
• Not recommended for individuals with a history of urinary retention.
• Avoid if you have a history of seizures or epilepsy.
• Should not be used in patients with severe dehydration.
• Contraindicated during the last stages of pregnancy.

The side effects of Cetirizine, Paracetamol, and Phenylephrine Hydrochloride Tablet may include:

• Drowsiness or fatigue
• Dry mouth
• Headache
• Nausea or stomach discomfort
• Dizziness
• Nervousness or restlessness
• Increased heart rate or blood pressure
• Difficulty in urination or urinary retention

Here are the precautions and warnings for Cetirizine, Paracetamol, and Phenylephrine Hydrochloride Tablet:

• Individuals with known allergies to any of the components, including Cetirizine, Paracetamol, or Phenylephrine Hydrochloride, should not take this medication.
• Patients with liver or kidney disease must exercise caution and consult a healthcare professional before use, as these conditions may affect drug metabolism and excretion.
• Alcohol consumption should be avoided as it may increase the risk of liver damage, especially when combined with Paracetamol.
• Do not exceed the recommended dosage, as excessive use of Paracetamol can lead to severe liver damage.
• Patients with heart conditions, high blood pressure, diabetes, or thyroid problems should use this medication with caution and under medical supervision.
• This medication may cause drowsiness or dizziness; avoid driving or operating heavy machinery until you know how it affects you.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as the potential risks and benefits should be carefully considered.

Following are the drug interactions for Cetirizine, Paracetamol, and Phenylephrine Hydrochloride Tablet:

• Alcohol and other central nervous system depressants may enhance drowsiness when taken with cetirizine.
• Paracetamol may interact with anticoagulants (blood thinners) like warfarin, requiring close monitoring of blood clotting time.
• Caution is advised when using paracetamol with other liver-affecting medications, as it may increase the risk of liver damage.
• Phenylephrine may interact with certain blood pressure medications, such as beta-blockers, leading to decreased effectiveness of both drugs.
• Monoamine oxidase inhibitors (MAOIs) should not be used concurrently with this medication due to potential severe side effects.
• Drugs that cause urinary retention, such as anticholinergics, may have additive effects when combined with phenylephrine.
• The effectiveness of cetirizine may be reduced when taken with antacids containing aluminum or magnesium.

Following are the food interactions for Cetirizine, Paracetamol, and Phenylephrine Hydrochloride Tablet:

• Grapefruit and grapefruit juice should be avoided as they can affect the metabolism of the medication, leading to increased levels of the drug in the body.
• Alcohol may intensify drowsiness and sedation, especially with Cetirizine, so it's best to limit or avoid alcohol consumption during treatment.
• Caffeine-rich foods and beverages might counteract the sedating effects of Cetirizine, potentially reducing its effectiveness.
• Spicy foods can potentially irritate the nasal passages and throat, which may be counterproductive when taking Phenylephrine for congestion relief.
• Dairy products might interfere with the absorption of Cetirizine, so it's advisable to separate the medication from dairy intake by a few hours.
• Consuming a balanced diet rich in fruits and vegetables can support the body's overall immune response, potentially enhancing the effectiveness of the medication.
• Stay well-hydrated by drinking adequate water, especially when taking Paracetamol, to support liver function and aid in the elimination of the medication's metabolites.
• Avoid excessive consumption of fatty or fried foods as they may affect the absorption and metabolism of the medication, potentially leading to increased side effects.

Cetirizine, Paracetamol, and Phenylephrine Hydrochloride Tablets should be stored in a cool, dry place, preferably in a medicine cabinet or a designated storage area, away from direct sunlight and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and effectiveness. It is crucial to keep the medication out of the reach of children and pets to prevent accidental ingestion. Do not store the tablets in the bathroom or kitchen, as these areas may have varying temperatures and humidity levels that can impact the medication's quality. Always check the expiration date regularly, and dispose of any unused or expired tablets responsibly. Proper disposal methods include returning the medication to a pharmacy or following local guidelines for pharmaceutical waste disposal, ensuring that the tablets are not flushed down the toilet or discarded with regular household waste.

Following are the quick tips for Cetirizine, Paracetamol, and Phenylephrine Hydrochloride Tablet:

• Consult your healthcare provider for the correct dosage and duration of treatment.
• Take the tablet with a full glass of water as directed.
• Do not crush, chew, or break the tablet, swallow it whole.
• Avoid alcohol consumption as it may intensify side effects.
• Inform your doctor about all medications you are taking to prevent drug interactions.
• Store the tablets at room temperature, away from moisture and direct sunlight.
• If you experience drowsiness, avoid driving or operating heavy machinery.