Colief (200mg) 10 Capsules

Mebeverine, the active ingredient in the 200mg capsule, exerts its therapeutic effect primarily through its action on smooth muscle cells in the gastrointestinal tract. It belongs to a class of drugs known as antispasmodics, and its mechanism of action involves the inhibition of calcium channels in smooth muscle cells. By blocking calcium entry, Mebeverine prevents the activation of myosin light-chain kinase, which is essential for muscle contraction. This inhibition leads to a reduction in gastrointestinal smooth muscle contractions, thereby relaxing the muscles and alleviating symptoms associated with gastrointestinal motility disorders, such as abdominal pain and discomfort. This targeted action on smooth muscle cells is the key to Mebeverine's effectiveness in managing gastrointestinal spasms and related conditions.

Mebeverine 200mg

Anticholinergic antispasmodic.

Capsule

The following are the uses of Mebeverine 200mg Capsule:

• Used for relieving stomach cramps and abdominal pain.
• Used to treat symptoms of irritable bowel syndrome (IBS) such as bloating, diarrhea, and constipation.
• Used to relax the muscles in the gut, easing painful muscle spasms.
• Used to improve bowel movement and reduce discomfort.
• Used for managing symptoms of diverticulitis and ulcerative colitis.
• Used to reduce muscle spasms in the bladder, aiding in urinary issues.
• Used to provide relief from menstrual cramps and associated pain.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• The appropriate dosage depends on factors like severity of the condition, age, weight, etc.
• Dosage guidelines are a general reference point, always consult a medical professional for personalized dosages.
• Typical adult dosage is 200mg 3 times a day, children's dosage may range from 50mg to 100mg three times a day.

In the case of an overdose of Mebeverine 200mg Capsules, individuals may experience intensified side effects such as drowsiness, dizziness, and gastrointestinal discomfort. It is important to remain calm and seek medical advice promptly. Contact a healthcare professional or local poison control center for guidance, as they can provide specific instructions based on the amount ingested and the individual's medical history. Quick action can help manage any potential adverse reactions and ensure the best outcome.

In the case of a missed dose of Mebeverine 200mg Capsule, it is advisable to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one. Avoid taking extra medicine to make up for the missed dose, as this may lead to an increased risk of side effects. It is important to maintain a consistent dosing schedule for optimal effectiveness. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track.

To take Mebeverine 200mg Capsule, swallow the capsule whole with a full glass of water, preferably with or after a meal, once or three times a day as directed by your healthcare professional.

Following are the conditions when Mebeverine 200mg Capsule should not be taken:

• Avoid if you have a known allergy to Mebeverine or any other similar medications.
• Do not take if you have a gastrointestinal obstruction or severe gastrointestinal conditions like ulcerative colitis, toxic megacolon, or gastrointestinal perforation.
• Contraindicated in individuals with severe kidney or liver disease.
• Not suitable for children under 12 years of age.
• Do not take if you have a rare genetic problem called porphyria.
• Avoid if you have a heart condition called tachycardia.
• Should not be used if you have recently had or are about to have abdominal surgery.

The side effects of Mebeverine 200mg Capsule may include:

• Dry mouth
• Dizziness
• Headache
• Nausea and vomiting
• Skin rashes
• Blurred vision
• Drowsiness
• Gastrointestinal discomfort

Following are the precautions and warnings for Mebeverine 200mg Capsule:

• Not suitable for individuals with known allergies to Mebeverine or any of its ingredients.
• Patients with gastrointestinal obstructions or severe kidney or liver diseases should exercise caution and consult a doctor before use.
• Mebeverine may cause drowsiness or blurred vision; patients should avoid driving or operating machinery until they know how the medication affects them.
• Alcohol consumption should be avoided as it may worsen side effects.
• Elderly patients may be more sensitive to the side effects; dosage adjustments might be necessary.
• Not recommended for children without medical advice.
• Women who are pregnant or breastfeeding should consult a doctor before taking this medication.

Following are the drug interactions for Mebeverine 200mg Capsule:

• It may interact with anticholinergic drugs, potentially causing increased side effects like dry mouth, constipation, and blurred vision.
• Mebeverine can enhance the effects of sedatives and alcohol, leading to increased drowsiness and impaired motor skills.
• Concomitant use with antispasmodic medications may result in additive effects and potential over-relaxation of smooth muscles.
• Drugs that affect liver enzymes, such as certain antifungal medications, can alter Mebeverine's metabolism and effectiveness.
• Mebeverine may have a reduced effect when taken with medications that speed up the movement of food through the gut, such as laxatives.
• It can increase the risk of bleeding when taken with anticoagulants, requiring close monitoring.
• Caution is advised when combining Mebeverine with antihypertensive medications, as it may affect blood pressure regulation.

Following are the food interactions for Mebeverine 200mg Capsule:

• Avoid consuming large amounts of grapefruit or grapefruit juice as it may interfere with the drug's metabolism and increase the risk of side effects.
• Alcohol consumption should be limited as it can exacerbate gastrointestinal symptoms and reduce the effectiveness of Mebeverine.
• Avoid high-fat meals as they may delay the absorption of Mebeverine, potentially affecting its onset of action.
• Caffeine intake should be moderated as it can stimulate the gastrointestinal tract and counteract the relaxing effects of Mebeverine on smooth muscles.
• Spicy foods should be consumed in moderation as they can irritate the digestive system and reduce the medication's efficacy.
• Avoid excessive consumption of dairy products, as they may increase stomach acidity and potentially reduce Mebeverine's effectiveness.
• Mebeverine may interact with certain herbal supplements like St. John's Wort, affecting its metabolism, so consult a healthcare professional before combining them.
• Stay hydrated by drinking enough water to ensure the optimal functioning of Mebeverine and maintain overall digestive health.

Mebeverine 200mg capsules should be stored in a cool, dry place, preferably at room temperature between 68-77°F (20-25°C). Protect the capsules from direct exposure to light and moisture by keeping them in their original packaging or a tightly sealed container. It is crucial not to store them in the bathroom or kitchen, as these areas may have temperature fluctuations. Always check the expiration date before use, and do not use the medication if it is expired. For disposal, do not throw the capsules into the garbage or flush them down the toilet. Instead, follow local guidelines for pharmaceutical waste disposal or consult a pharmacist for advice on safe disposal methods. Keep the medication away from children and pets to prevent accidental ingestion.

Following are the quick tips for Mebeverine 200mg Capsule:

• Consult your doctor before taking this medication, especially if you have liver or kidney issues.
• Take the capsule as directed by your doctor; do not exceed the prescribed dosage.
• Swallow the capsule whole with water; do not crush or chew it.
• Take the medicine at evenly spaced intervals to maintain a consistent level in your body.
• Avoid alcohol consumption while taking this medication as it may worsen side effects.
• Inform your doctor about all medications you are currently taking to prevent any drug interactions.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.

Mebeverine Hydrochloride is a medication often used to treat irritable bowel syndrome and gastrointestinal disorders under many circumstances. Depending on the patient's age, health history, and other factors such as concurrent medications, lab tests may be required. It is important to inform your doctor about all the medications you are taking, including over-the-counter drugs and herbal supplements, to ensure that the medication is working safely and effectively. Patients taking Mebeverine Hydrochloride may require specific lab tests, including liver function tests, electrolyte levels, white blood cell count, and bacterial/yeast infection tests. Liver function tests are crucial as the medication is excreted through the liver. Electrolyte levels need to be monitored since Mebeverine Hydrochloride can disrupt the balance of sodium, potassium, and magnesium, causing side effects such as dizziness and muscle weakness. White blood cell count is important to check for neutropenia, which can be caused by the medication. Bacterial and yeast infection tests are necessary as these infections can develop while taking Mebeverine Hydrochloride. Consulting with a qualified medical professional is essential for personalized advice on the lab tests required based on the patient's condition and medical history.