Cotecxin (60mg) 8 Tablets

Artemisinin, the active component in the Artemisinin 60mg Tablet, exhibits a unique mechanism of action that targets the parasite responsible for malaria. It selectively binds to a specific protein called PfATP6, which is found in the food vacuole of the Plasmodium falciparum parasite. This binding disrupts the parasite's ability to eliminate toxic byproducts, such as heme, leading to the accumulation of reactive oxygen species (ROS) and free radicals. The increased oxidative stress within the parasite causes damage to its cellular structures, particularly the membrane and vital proteins, ultimately resulting in the parasite's death. This mechanism is distinct from that of other antimalarial drugs, making artemisinin a valuable component in the treatment of malaria, especially in combination therapies to combat drug-resistant strains.

Artemisinin 60mg

Antimalarial medication.

Tablet

The following are the uses of Artemisinin 60mg Tablet:

• Used for treating malaria, especially severe cases caused by Plasmodium falciparum.
• Used for its potent anti-malarial properties to combat the parasite effectively.
• Used for reducing the number of parasites in the blood, alleviating symptoms.
• Used for managing malaria-related complications and preventing severe illness.
• Used for its fast-acting nature, providing rapid relief from malaria symptoms.
• Used for treating uncomplicated and complicated cases of malaria.
• Used for supporting the management of multi-drug resistant malaria strains.
• Used for its effectiveness in regions with high malaria prevalence.

In the case of an overdose of Artemisinin 60mg Tablets, it is important to recognize the potential severity of the situation. Symptoms may include an increased heart rate, dizziness, and in extreme cases, respiratory distress. If an overdose is suspected, it is vital to seek medical advice promptly. Quick action can ensure appropriate treatment and reduce the risk of adverse health effects. Immediate consultation with a healthcare professional is recommended to manage the situation effectively.

In the case of a missed dose of Artemisinin 60mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. It is crucial to maintain a consistent medication routine, but if you miss a dose, consult your healthcare provider for guidance on how to proceed and ensure you're taking the medication correctly.

To take Artemisinin 60mg Tablets, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically once or twice daily as prescribed.

Following are the conditions when Artemisinin 60mg Tablet should not be used:

• Do not take if you have a known allergy to Artemisinin or any other ingredients in the tablet.
• Avoid using this medication if you have a history of prolonged QT intervals or heart rhythm disorders.
• Not suitable for individuals with severe liver or kidney disease.
• Should not be used during pregnancy or breastfeeding.
• Do not administer to children without medical advice.
• Contraindicated in patients with a known sensitivity to Artemisinin-based drugs.
• Avoid if you have a history of severe allergic reactions to other medications.
• Not recommended for individuals with a history of seizures or epilepsy.
• Discontinue use if you experience severe dizziness, fainting, or any other serious side effects.

The side effects of Artemisinin 60mg Tablet may include:

• Nausea and vomiting
• Dizziness
• Palpitations or increased heart rate
• Diarrhea
• Drowsiness or fatigue
• Skin rashes or itching
• Abdominal pain

Following are the precautions and warnings:

• Artemisinin 60mg Tablet should not be used in patients with a known allergy or hypersensitivity to artemisinin or other related compounds.
• This medication is intended for the treatment of malaria and should not be used for other conditions without medical supervision.
• Patients with underlying liver or kidney disease should use this medication with caution and under medical supervision as dosage adjustments may be necessary.
• Artemisinin can cause dizziness and sleepiness, so patients should avoid driving or operating heavy machinery until they know how this medication affects them.
• It is important to complete the full course of treatment as prescribed, even if symptoms improve, to ensure complete eradication of the malaria parasite.
• Pregnant and breastfeeding women should consult a healthcare professional before taking this medication as its safety during pregnancy and breastfeeding is not well established.
• This medication may interact with other drugs, including antiretrovirals, antifungals, and certain antibiotics, so patients should inform their doctor of all medications they are currently taking.
• Keep this medication out of reach of children and store it in a cool, dry place, away from direct sunlight.

Following are the drug interactions for Artemisinin 60mg Tablet:

• Artemisinin may reduce the effectiveness of antimalarial drugs like chloroquine or mefloquine when used concurrently.
• Co-administration with certain immunosuppressants, such as cyclosporine, may lead to increased immunosuppression.
• Taking Artemisinin with certain antibiotics like clarithromycin or erythromycin can alter the effectiveness of both medications.
• It can interact with anti-retroviral drugs used for HIV treatment, potentially affecting viral load and treatment outcomes.
• Artemisinin might affect the metabolism of medications processed by the liver, including some statins and antifungal drugs.
• Use with drugs that prolong the QT interval, such as certain antiarrhythmic medications, may increase the risk of cardiac arrhythmias.
• Caution is advised when combining with other herbs or supplements that have similar effects, as this may lead to additive or synergistic interactions.

Following are the food interactions of Artemisinin 60mg Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can increase the levels of Artemisinin in the blood, potentially leading to increased side effects.
• Alcohol intake should be limited or avoided as it may decrease the effectiveness of Artemisinin and increase the risk of liver-related side effects.
• Fatty meals can delay the absorption of Artemisinin, so it is best to take the medication on an empty stomach or with a light meal.
• Avoid high-fat diets as they may reduce the absorption and effectiveness of the drug.
• Garlic supplements may decrease the bioavailability of Artemisinin, so consult your doctor if you regularly consume garlic supplements.
• Ginger, when taken in large amounts, may interact with Artemisinin and increase the risk of bleeding.
• Green leafy vegetables rich in vitamin K can potentially reduce the anticoagulant effect of Artemisinin.
• Consult your doctor if you regularly consume herbal teas or supplements, as some herbs may interact with Artemisinin's action.

Artemisinin 60mg Tablets should be stored in a cool, dry area, preferably in a sealed container, away from direct sunlight and moisture to maintain their potency. It is recommended to keep the tablets in their original packaging, ensuring the container is tightly sealed to prevent exposure to air and humidity. Avoid storing them in the bathroom or kitchen, as these areas often have higher temperatures and humidity levels that can degrade the medication. Always check the expiration date, and dispose of any unused or expired tablets responsibly. Do not flush them or throw them into the trash; instead, follow local guidelines for pharmaceutical waste disposal. Keep the medication safely locked away from children and pets to prevent accidental consumption.

Following are the quick tips for Artemisinin 60mg Tablet:

• Store the tablets in a cool, dry place, away from direct sunlight or moisture.
• Take the tablet orally with a full glass of water, preferably at the same time each day.
• Swallow the tablet whole; do not crush, chew, or break it.
• Ensure you complete the full course of medication as prescribed by your doctor.
• Inform your doctor if you have any known allergies or are taking other medications.
• Do not share this medication with others, even if their symptoms appear similar.
• Regularly monitor your health and report any unusual symptoms to your healthcare provider.