Cremazole (1%) 60ml Skin Lotion

Cremazole (1%) 60ml Skin Lotion

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  • Manufacturer VALOR
  • Generic Name

    Clotrimazole

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Laboratory Screening
  • Description

    Clotrimazole Lotion works by specifically targeting and inhibiting the growth of certain types of fungi, particularly those belonging to the group of dermatophytes, which are responsible for causing various skin infections. It interferes with the synthesis of ergosterol, a crucial component of fungal cell membranes. By binding to the fungal enzyme lanosterol 14-alpha-demethylase, clotrimazole blocks the conversion of lanosterol to ergosterol, leading to the disruption of membrane integrity and function. This impairment in membrane structure weakens the fungal cells, hindering their growth and replication, and ultimately leading to their elimination.

  • Ingredients

    Clotrimazole

  • Drug Class

    Antifungal lotion

  • Dosage Form

    Lotion

  • Uses

    The following are the uses of Clotrimazole Lotion:

    • Used for treating fungal skin infections like athlete's foot, jock itch, and ringworm.
    • Used for relieving itching, redness, and discomfort caused by these infections.
    • Used for preventing the spread of fungal infections to other body parts.
    • Used for maintaining skin health and preventing recurrence of infections.
    • Used for treating fungal infections in skin folds and sensitive areas.
    • Used for soothing inflamed and irritated skin.
    • Used for restoring the skin's natural barrier function.
    • Used for providing targeted relief from fungal-related symptoms.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Female genital tract- A small amount of cream should be applied topically to the vaginal mucosa at bedtime for 7 days.
    • Jock itch- Apply the cream over the affected skin area twice daily for 10 days.
    • Skin infections- Cream is applied sparingly to cover the affected area entirely. The cream is not washed off after application. To prevent contamination, a thin layer is applied once or twice a day depending on the severity of the infection.
    • In atopic dermatitis, cream is applied two or three times a day in conjunction with topical steroids.
    • In case of extensive skin lesions, the cream should be applied thinly and widely to cover the entire affected skin area.
  • In case of Overdose

    In the case of an overdose of Clotrimazole Lotion, it is unlikely to cause significant harm. However, if a large amount is ingested or applied excessively, it may lead to increased skin irritation, redness, or itching at the application site. In the event of such an overdose, the best course of action is to discontinue use and thoroughly wash the affected area with mild soap and water. It is advisable to consult a healthcare professional for further guidance if any adverse effects persist or if there are concerns regarding excessive use.

  • Missed Dose

    In the case of a missed dose of Clotrimazole Lotion, it is important to apply the medication as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one. Do not apply extra lotion to make up for the missed dose. If you miss multiple doses, contact your healthcare professional for advice on how to proceed, as they may provide specific instructions for your individual treatment plan. Remember, it's crucial to adhere to the prescribed schedule to ensure the medication's effectiveness.

  • How To Use

    To apply Clotrimazole Lotion, clean and dry the affected skin area, then apply a thin layer of the lotion to the skin, gently rubbing it in, usually twice a day or as directed by your healthcare professional.

  • When Not to Use

    Here are the conditions or situations when Clotrimazole Lotion should not be used:

    • Do not use if you have a known allergy or sensitivity to Clotrimazole or any of the lotion's components.
    • Avoid using on broken or severely damaged skin.
    • Not recommended for individuals with a history of skin reactions or sensitivity to similar antifungal medications.
    • Do not use on areas with open wounds or severe skin infections.
    • Contraindicated for use around the eyes, mouth, or other mucous membranes.
    • Should not be used on children without medical supervision.
    • Do not share the lotion with others, even if they have similar symptoms.
  • Side Effects

    The possible side effects of Clotrimazole Lotion may include:

    • Skin irritation at the application site
    • Redness or swelling
    • Itching or burning sensation
    • Dry skin
    • Rash or hives
    • Blistering or peeling skin
    • Allergic reaction (rare)
    • Mild skin discomfort
  • Precautions & Warnings

    Following are the precautions and warnings for Clotrimazole Lotion:

    • Avoid contact with eyes, nose, and mouth. In case of accidental contact, rinse thoroughly with water.
    • Do not apply to open wounds, burns, or areas of broken skin.
    • Wash your hands before and after applying the lotion to prevent the spread of infection.
    • If you are pregnant or breastfeeding, consult your doctor before using this medication.
    • Discontinue use and seek medical attention if you experience severe burning, itching, or irritation at the application site.
    • For external use only. Do not ingest or swallow the lotion.
    • Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
  • Drug Interactions

    Following are the drug interactions for Clotrimazole Lotion:

    • Topical corticosteroids, when used with Clotrimazole Lotion, can increase the risk of skin atrophy and other adverse effects.
    • Antifungal drugs like ketoconazole or itraconazole may enhance the absorption of clotrimazole, potentially leading to increased side effects.
    • Avoid using other topical medications without consulting a healthcare professional, as they may alter the effectiveness of Clotrimazole Lotion.
    • Clotrimazole may increase the bioavailability of oral hypoglycemic agents, requiring careful monitoring of blood glucose levels.
    • Drugs metabolized by the liver, such as certain oral contraceptives, may have altered blood levels when used with Clotrimazole.
    • The effectiveness of Clotrimazole Lotion may be reduced if used with other topical agents containing alcohol or acetone.
    • Drug interactions with Clotrimazole Lotion are also possible with immunosuppressants, potentially increasing the risk of infection.
  • Food Interactions

    Following are the food interactions to consider with Clotrimazole Lotion:

    • Grapefruit and grapefruit juice consumption should be avoided as they may influence the metabolism of Clotrimazole, potentially leading to increased levels in the body and heightened risk of side effects.
    • Alcoholic beverages are generally safe to consume with Clotrimazole Lotion, but excessive alcohol intake might increase skin sensitivity and dryness.
    • Foods high in fat do not significantly affect Clotrimazole absorption, but a balanced diet is advisable for overall health.
    • Avoid applying the lotion immediately after a hot or spicy meal, as it may cause temporary skin irritation or discomfort.
    • Caffeinated drinks might slightly increase skin sensitivity, so consider reducing intake during treatment.
    • Staying hydrated by drinking plenty of water can help maintain skin moisture, which is beneficial when using Clotrimazole Lotion.
    • Certain herbal teas, like green tea, may have a soothing effect on the skin and can be consumed alongside the medication.
    • There are no specific food restrictions, but maintaining a healthy diet supports overall skin health during treatment.
  • Storage/Disposal

    Clotrimazole Lotion should be stored in a controlled environment, preferably at room temperature, between 20°C and 25°C (68°F to 77°F). Protect the lotion from excessive heat, direct sunlight, and moisture by keeping it in its original container, tightly sealed. Ensure the container is stored in a dry and cool place, away from the reach of children and pets. Do not refrigerate the lotion as it may alter its consistency. Always check the expiration date, and if the lotion has expired or is no longer needed, proper disposal is crucial. Contact your pharmacist or local waste disposal company for guidance on how to safely discard the medication, as flushing it down the toilet or pouring it into drainage systems should be avoided.

  • Quick Tips, if any

    Following are the quick tips for Clotrimazole Lotion:

    • Clean and dry the affected area before applying the lotion.
    • Apply a thin layer of lotion to the affected skin and nearby areas.
    • Gently rub the lotion into the skin, ensuring complete coverage.
    • Wash your hands after application to avoid accidental contact with eyes or mouth.
    • Use the lotion as directed, typically twice daily, for the full prescribed duration.
    • Avoid covering the treated area with tight clothing or bandages to allow the skin to breathe.
    • If irritation or redness persists or worsens, consult your healthcare provider.
  • Laboratory Screening

    When taking Betamethasone Dipropionate 0.05% and Clotrimazole 1%, it is crucial to be aware of the potential side effects and drug interactions. One of the important things to be aware of is the possibility of elevated blood pressure. Betamethasone Dipropionate 0.05% is a potent corticosteroid that can cause blood pressure elevations in some individuals, thereby necessitating regular blood pressure monitoring to proactively address any complications or development of hypertension. Given the risk of increased blood sugar levels caused by both betamethasone and clotrimazole, it is critical for individuals who are diabetic or pre-diabetic to undertake regular blood sugar assessments. This is imperative to ensure that the treatment regime does not disrupt normal glucose levels and that adjustments are made accordingly. Given the potential of betamethasone to stress the liver, regular liver function tests are necessary to identify any abnormalities in liver enzyme levels or liver tissue health. Long-term use of betamethasone may lead to kidney function impairment. Consequently, kidney function tests are essential to identify any changes in kidney function caused by the medication. It is essential to be aware that this list is not comprehensive and that consulting with a healthcare professional is paramount before taking these medications. Furthermore, undergoing regular checkups ensures that the treatment is both safe and effective for your specific needs.

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