Cresar-H (80/25mg) 20 Tablets

Hydrochlorothiazide and Telmisartan work synergistically in this combination medication to lower blood pressure. Hydrochlorothiazide is a diuretic that increases urine production, leading to the removal of excess fluid and sodium from the body, which helps to reduce blood volume and subsequently lowers blood pressure. Telmisartan, on the other hand, is an angiotensin II receptor blocker (ARB). It blocks the effects of angiotensin II, a hormone that normally causes blood vessels to narrow, by blocking the angiotensin II receptors. This action leads to the relaxation of blood vessels, which in turn reduces blood pressure by allowing blood to flow more easily through the dilated vessels.

Hydrochlorothiazide 25mg, Telmisartan 80mg

Angiotensin II Receptor Blocker, Diuretic.

Tablet

The following are the uses of Hydrochlorothiazide 25mg, Telmisartan 80mg Tablet:

• Used for treating high blood pressure (hypertension)
• Used to lower blood pressure and reduce the risk of heart disease and stroke
• Used to improve blood flow and reduce strain on the heart
• Used to manage fluid retention (edema) associated with hypertension
• Used to promote kidney function by reducing excess fluid and salt
• Used for long-term management of hypertension, often in combination with other medications
• Used to prevent the narrowing of blood vessels, improving blood circulation
• Used as part of a comprehensive treatment plan for cardiovascular health

In the case of an overdose of Hydrochlorothiazide 25mg and Telmisartan 80mg Tablet, individuals may experience symptoms such as dizziness, fatigue, and an increased heart rate. It is important to seek medical advice if you suspect an overdose. The effects can vary depending on the individual's health and the amount ingested. Common symptoms may include hypotension, electrolyte imbalances, and in severe cases, kidney dysfunction. Prompt medical intervention is advised to manage potential complications.

In the case of a missed dose of Hydrochlorothiazide 25mg, it is generally recommended to take the missed dose as soon as you remember, unless it is close to the time for your next scheduled dose. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. For Telmisartan 80mg Tablet, if a dose is missed, take it as soon as you remember, but if it's near the time for your next dose, skip the missed dose and continue with your regular dosing. It's important to try to take your medications at the same time each day to maintain a consistent routine.

To take the Hydrochlorothiazide 25mg, Telmisartan 80mg Tablet, simply swallow the tablet whole with a glass of water, preferably at the same time each day, as directed by your healthcare provider.

Following are the conditions/situations when Hydrochlorothiazide 25mg, Telmisartan 80mg Tablet should not be used:

• Should not be used in individuals with a known allergy to Hydrochlorothiazide, Telmisartan, or any of its components.
• Contraindicated in patients with severe renal impairment or patients with anuria (inability to produce urine).
• Not recommended for individuals with significant liver disease or progressive liver disorders.
• Should not be used in patients with severe hypokalemia (low potassium levels) or hypercalcemia (high calcium levels).
• Contraindicated during pregnancy, especially in the second and third trimesters.
• Not suitable for individuals with a history of angioedema (swelling of deep layers of the skin) or those who are sensitive to other angiotensin II receptor blockers.
• Should be avoided in patients with severe diarrhea or vomiting as it may lead to dehydration.
• Discontinue use if you experience a severe allergic reaction, including swelling of the face, lips, throat, or tongue, or difficulty breathing.

The side effects of Hydrochlorothiazide 25mg, Telmisartan 80mg Tablet may include:

• Dizziness or lightheadedness
• Fatigue or weakness
• Nausea and vomiting
• Diarrhea or constipation
• Muscle cramps or joint pain
• Increased sensitivity to sunlight (photosensitivity)
• Skin rash or itching
• Low blood pressure (hypotension)

Following are the precautions and warnings for Hydrochlorothiazide 25mg, Telmisartan 80mg Tablet:

• This medication is contraindicated in patients with a known allergy or hypersensitivity to hydrochlorothiazide, telmisartan, or any other components of the tablet.
• Patients with a history of renal impairment or those at risk of developing renal problems should undergo regular kidney function monitoring while on this medication.
• Caution is advised for individuals with a history of liver disease, as telmisartan may affect liver function. Regular liver function tests may be required.
• Hydrochlorothiazide can cause significant potassium loss, leading to hypokalemia. Monitoring of potassium levels is essential, especially in patients with cardiac conditions.
• This medication may cause postural hypotension, especially during initial dose adjustments or when combined with other antihypertensive drugs.
• Telmisartan may cause fetal harm during pregnancy. Women of childbearing age should use effective contraception while on this medication.
• Patients with a history of angioedema should be aware that hydrochlorothiazide may exacerbate this condition. Discontinue use if angioedema occurs.
• Elderly patients may be more susceptible to the side effects of this medication, particularly electrolyte imbalances and hypotension.

Following are the drug interactions for Hydrochlorothiazide 25mg, Telmisartan 80mg Tablet:

• Lithium levels may be increased with thiazide diuretics like Hydrochlorothiazide, potentially leading to lithium toxicity. Close monitoring of lithium levels is recommended.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce the blood pressure-lowering effect of Telmisartan and may increase the risk of kidney problems, especially in dehydrated patients.
• Hydrochlorothiazide may decrease the elimination of calcium channel blockers, potentially increasing their blood levels and side effects.
• The blood pressure-lowering effect of Telmisartan may be reduced by corticosteroids, which can also increase the risk of hypokalemia.
• Telmisartan may increase serum potassium levels, and its use with potassium-sparing diuretics, potassium supplements, or potassium-containing salt substitutes may lead to hyperkalemia.
• The effectiveness of Hydrochlorothiazide may be reduced by agents that increase urinary pH, such as carbonic anhydrase inhibitors.
• Caution is advised when combining Telmisartan with other medications that affect the renin-angiotensin system, as it may lead to increased risk of hypotension and renal impairment.
• Hydrochlorothiazide may increase the risk of digoxin toxicity by decreasing renal clearance of digoxin.

Following are the food interactions for Hydrochlorothiazide 25mg, Telmisartan 80mg Tablet:

• Alcohol consumption should be limited or avoided as it may increase the risk of dizziness and lightheadedness, especially when standing up due to the blood pressure-lowering effect of the medication.
• Grapefruit and grapefruit juice should be consumed with caution as they may interact with Telmisartan, potentially leading to increased drug levels in the body and an increased risk of side effects.
• Maintain a balanced diet low in sodium (salt) and rich in potassium. Hydrochlorothiazide can cause potassium loss, so include potassium-rich foods like bananas, oranges, and spinach in your diet.
• Avoid excessive salt intake as it can reduce the effectiveness of blood pressure-lowering medications.
• Stay well-hydrated by drinking enough fluids, especially if you experience increased urination due to the diuretic effect of Hydrochlorothiazide.
• Avoid or limit caffeine intake as it may increase blood pressure and interact with the medication's effects.
• Inform your healthcare provider if you have a history of kidney or liver disease, as these conditions may affect the metabolism and elimination of the medication.

Hydrochlorothiazide 25mg, Telmisartan 80mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. It is crucial to keep the tablets in their original packaging, tightly sealed, to maintain their integrity. Avoid storing them in areas with excessive heat or humidity, such as bathrooms or kitchen cabinets near stoves, as these conditions can degrade the medication. When disposing of unused or expired tablets, do not flush them or throw them into the garbage. Instead, consult your pharmacist or local waste management guidelines for safe disposal methods to minimize environmental impact. Keep the medication away from children and pets to prevent accidental ingestion.

Following are the quick tips for Hydrochlorothiazide 25mg and Telmisartan 80mg Tablet:

• Always take the medication as directed by your doctor.
• Take the tablet with a full glass of water for easy swallowing.
• Maintain a consistent schedule for taking your medication daily.
• Avoid salt substitutes while on this medication unless advised otherwise.
• Regular blood pressure monitoring is essential during treatment.
• Inform your doctor about all medications you are taking.
• Store the tablets in a cool, dry place, away from direct sunlight.
• Contact your healthcare provider if you experience dizziness or lightheadedness.