Cutis (1%) 10g Cream

Cutis (1%) 10g Cream

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  • Manufacturer TABROS PHARMACEUTICALS (PVT.) LTD.
  • Generic Name Terbinafine

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Laboratory Screening
  • Description

    Terbinafine cream, when applied topically, exerts its antifungal activity primarily by inhibiting a key enzyme called squalene epoxidase. This enzyme plays a crucial role in the biosynthesis of ergosterol, a vital component of the fungal cell membrane. By blocking the action of squalene epoxidase, terbinafine disrupts the production of ergosterol, leading to the accumulation of squalene and other sterol intermediates within the fungal cell. This disruption in sterol synthesis weakens the cell membrane integrity of susceptible fungi, ultimately resulting in fungal cell death. The selective inhibition of squalene epoxidase makes terbinafine highly effective against a range of dermatophytes and certain other fungi, while minimizing adverse effects on human cells, which do not rely on ergosterol for their membrane structure.

  • Ingredients

    Terbinafine
  • Drug Class

    Antifungal

  • Dosage Form

    Cream

  • Uses

    The following are the uses of Terbinafine Cream:

    • Used for treating fungal skin infections such as athlete's foot, jock itch, and ringworm.
    • Used for relieving itching, redness, and discomfort associated with fungal infections.
    • Used for inhibiting the growth and spread of fungi on the skin's surface.
    • Used for clearing up fungal infections, improving skin appearance and texture.
    • Used for preventing the recurrence of fungal infections when used as directed.
    • Used for treating fungal nail infections, promoting healthy nail growth.
    • Used for maintaining skin and nail hygiene, reducing the risk of fungal colonization.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Terbinafine Hydrochloride 1% is a topical antifungal drug used to treat fungal infections of the skin and nails such as athletes' foot, jock itch, ringworm, and fungal nails.
    • It is available in cream or gel form and is applied topically to the affected area.
    • The usual dose for adults and children aged 12 years and older is to apply the cream or gel to the affected area once daily for up to 4 weeks. While children younger than 12 years of age should use it twice daily for up to 4 weeks.
    • To get the most benefit, apply the medication at regular intervals and consistently follow the dosing schedule. Ensure to read the medication guide provided by the pharmacist before starting the treatment.
    • If you miss a dose, apply it as soon as possible, but if it is close to the next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
    • It is important to wash your hands after applying the cream or gel to avoid spreading the medication to other areas of the body or to your eyes.
    • Be sure to inform your doctor about all your medical conditions, medications, and supplements you are taking, as well as any allergies you may have.
  • In case of Overdose

    In the case of an overdose of Terbinafine Cream, it is important to note that the cream is for topical use only, and the risk of adverse effects from excessive application is low. However, if someone has ingested a large amount of the cream, they may experience gastrointestinal symptoms such as nausea, abdominal pain, or diarrhea. In such instances, contacting a healthcare professional or poison control center is recommended for further advice and to determine the appropriate course of action.

  • Missed Dose

    In the case of a missed dose of Terbinafine Cream, it is important to apply the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not apply extra cream to make up for the missed dose, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or asking someone to remind you to help maintain consistency in your treatment plan. Consult your healthcare provider if you have any concerns or questions regarding missed doses and the proper usage of Terbinafine Cream.

  • How To Use

    To apply Terbinafine Cream, clean and dry the affected skin area, then apply a thin layer of the cream, gently rubbing it into the skin once or twice daily, or as directed by your healthcare provider, covering the entire affected area and its immediate surrounding skin.

  • When Not to Use

    Here are the conditions and situations when Terbinafine Cream should not be used:

    • Do not use if you are allergic to terbinafine or any other antifungal medications.
    • Avoid using on open wounds, burns, or severely broken skin.
    • Not recommended for individuals with a history of liver or kidney disease.
    • Should not be used on areas of skin affected by other skin conditions like psoriasis, eczema, or severe skin inflammation.
    • Avoid using near the eyes, mouth, or other mucous membranes.
    • Do not use on children without medical advice, as the safety and effectiveness in children may vary.
    • Not suitable for individuals with a history of sensitivity or reactions to similar creams or their ingredients.
    • Discontinue use and consult a doctor if you develop severe or persistent skin irritation, redness, or swelling at the application site.
  • Side Effects

    The side effects of Terbinafine Cream may include:

    • Skin irritation or redness at the application site
    • Itching or burning sensation
    • Dry skin
    • Peeling or flaking of the skin
    • Mild rash
    • Allergic reactions (such as hives, swelling, or difficulty breathing)
    • Increased sensitivity to sunlight
    • Skin discoloration or hyperpigmentation
  • Precautions & Warnings

    Following are the precautions and warnings for Terbinafine Cream:

    • Avoid using the cream on open wounds, broken skin, or near the eyes, nose, or mouth.
    • Wash your hands thoroughly after applying the cream to avoid accidental contact with sensitive areas.
    • Discontinue use and consult a doctor if you experience severe irritation, redness, or swelling at the application site.
    • Terbinafine Cream is for external use only and should not be ingested.
    • Inform your healthcare provider if you have any liver or kidney problems before using this medication.
    • Avoid using other topical medications or products without consulting your doctor to prevent potential interactions.
    • This medication may cause an allergic reaction in some individuals; seek immediate medical attention if you experience symptoms like difficulty breathing or hives.
  • Drug Interactions

    Following are the drug interactions for Terbinafine Cream:

    • Terbinafine may interact with oral antifungal medications like itraconazole, potentially increasing the risk of liver-related side effects. Close monitoring of liver function is advised.
    • Topical corticosteroids, when used with Terbinafine, may mask the symptoms of a fungal infection, allowing it to worsen.
    • Using Terbinafine with other topical medications may increase skin irritation.
    • Warfarin interaction is possible, as Terbinafine may affect the absorption of vitamin K, which is essential for blood clotting.
    • The cream may reduce the effectiveness of live vaccines if applied to the vaccination site.
    • It can also interact with drugs that prolong the QT interval, such as certain antiarrhythmic medications.
    • Alcohol-based products may enhance the absorption of topical Terbinafine, potentially increasing the risk of side effects.
  • Food Interactions

    Following are the food interactions to be aware of when using Terbinafine Cream:

    • Alcohol consumption should be limited or avoided during treatment as it can increase skin sensitivity and the risk of side effects.
    • Grapefruit and grapefruit juice should be consumed cautiously as they may affect the metabolism of Terbinafine, potentially increasing its levels in the body and the risk of adverse reactions.
    • Caffeine intake may need to be monitored as it can influence liver function, and Terbinafine is metabolized in the liver.
    • Fatty or greasy foods are not directly contraindicated but maintaining a healthy diet is recommended to support overall skin health.
    • Spicy foods should be consumed in moderation as they can cause skin flushing or irritation, especially if you have sensitive skin.
    • Avoid any known food allergens, as Terbinafine may increase skin sensitivity and potentially exacerbate allergic reactions.
    • There are no specific dietary restrictions with Terbinafine Cream, but staying hydrated and maintaining a balanced diet can support the overall healing process.
    • Consult your healthcare provider if you have concerns about specific food interactions or if you experience any unusual symptoms while using Terbinafine Cream.
  • Storage/Disposal

    Terbinafine Cream should be stored in a cool and dry place, preferably at room temperature (around 20-25°C), away from direct sunlight and moisture. Keep the cream in its original container, tightly sealed, to maintain its integrity and prevent contamination. Avoid storing it in bathrooms or kitchens, as temperature fluctuations and humidity can impact its effectiveness. Pay attention to the expiration date on the packaging, and do not use the cream beyond this date. When disposing of any leftover or expired Terbinafine Cream, do not flush it or pour it down the drain. Instead, follow local guidelines or consult a pharmacist for safe disposal methods to minimize environmental impact. Ensure the cream is kept out of children's reach to prevent accidental exposure.

  • Quick Tips, if any

    Following are the quick tips for Terbinafine Cream:

    • Wash and dry the affected area before applying the cream to ensure better absorption.
    • Apply a thin layer of cream to the affected skin and gently rub it in until absorbed.
    • Wash your hands after applying the cream to avoid accidental contact with eyes or mouth.
    • Avoid applying the cream to broken or irritated skin; if irritation occurs, stop using it.
    • Do not cover the treated area with bandages or airtight dressings unless directed by a doctor.
    • Continue using the cream for the full prescribed duration, even if symptoms improve.
    • Store the cream at room temperature, away from direct sunlight and moisture.
  • Laboratory Screening

    Terbinafine Hydrochloride 1%, a medication used to treat fungal infections of the skin and nails, may require complementary laboratory tests to monitor progress and ensure its effectiveness. These tests are essential to maintain overall health and detect any potential abnormalities. While on this medication, regular blood tests are necessary to monitor your overall health. Your doctor may opt to check your blood cell count, liver and kidney function, and cholesterol levels to ensure the medication is not causing any harm to your body. Furthermore, since Terbinafine Hydrochloride can put stress on your liver, your doctor may recommend additional liver function tests to measure the impact on your liver enzymes and overall liver health. To ensure the medication is effective in treating the fungal skin infection, frequent examinations of the skin are necessary. For infections related to nails, your doctor may compare nails to monitor the rate of healthy nail growth and infection improvement. It is important to note that the frequency and type of lab tests needed will depend on individual circumstances and the severity of the condition being treated. Close monitoring and adherence to any testing protocols prescribed by your doctor while taking Terbinafine Hydrochloride 1% is crucial to ensure the medication is effective and to minimize any potential risks or side effects.

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