D-Cap (50000IU) 30 Capsules

Cholecalciferol, also known as vitamin D3, has a specific mechanism of action. When administered, cholecalciferol is absorbed in the small intestine and enters the bloodstream. It then undergoes two sequential hydroxylations first in the liver, where it is converted to 25-hydroxyvitamin D (calcidiol), and subsequently in the kidneys, where it is converted to its active form, 1,25-dihydroxyvitamin D (calcitriol). Calcitriol is the biologically active form of vitamin D, acting as a hormone. It binds to vitamin D receptors (VDR) in various target tissues, primarily in the intestines, bones, and kidneys. This binding activates specific genes that regulate calcium and phosphate metabolism. In the intestines, calcitriol enhances calcium and phosphate absorption, promoting bone mineralization. In the kidneys, it promotes calcium reabsorption and stimulates the production of calcitriol, forming a feedback loop. Additionally, cholecalciferol plays a role in immune function and cell proliferation through its interaction with VDRs in immune cells and various tissues.

Cholecalciferol 50,000iu

Vitamin D analog

Capsule

The following are the uses of Cholecalciferol 50,000iu Capsule:

• Used for treating and preventing Vitamin D deficiency
• Used to maintain bone health and calcium absorption
• Used in the management of osteoporosis
• Used for supporting immune function and reducing inflammation
• Used to improve muscle strength and physical performance
• Used as a supplement during pregnancy and breastfeeding
• Used to enhance mood and cognitive function
• Used in combination with calcium for overall bone and joint health

The following dosage regimen is to be followed:

• Adults

The Recommended Dietary Allowance for adults is 600 IU daily

• Geriatric

The RDA for people 70 years or above is 800 IU daily

• Children

To be used as per doctor's recommendation

In the case of an overdose of Cholecalciferol 50,000 IU capsules, symptoms may include nausea, vomiting, weakness, headache, and loss of appetite. Severe cases can lead to kidney damage, irregular heartbeat, and confusion. Prompt medical intervention is necessary, as treatment may involve managing symptoms, correcting electrolyte imbalances, and addressing any potential organ damage. It is crucial to seek medical advice if an overdose is suspected to prevent potential complications.

In the case of a missed dose of Cholecalciferol 50,000 IU Capsule, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare provider for guidance on how to get back on track with your vitamin D supplementation.

To take Cholecalciferol 50,000 IU capsules, swallow the capsule whole with a glass of water, preferably with a meal or as directed by your healthcare professional, once a week or as instructed by your doctor.

Following are the conditions/situations when Cholecalciferol 50,000 IU Capsule should not be taken:

• Should not be used in individuals with a known hypersensitivity or allergy to vitamin D or any of the excipients in the capsule.
• Contraindicated in patients with hypercalcemia (high blood calcium levels) or conditions that cause calcium levels to increase, such as primary hyperparathyroidism.
• Not recommended for individuals with uncontrolled hyperphosphatemia (high blood phosphate levels).
• Should not be used in patients with evidence of vitamin D toxicity.
• Contraindicated in patients with renal stones or conditions that increase the risk of renal calcification.
• Not suitable for individuals with non-metastatic skeletal disorders (such as idiopathic hypercalciuria).
• Should be used with caution and avoided in patients with conditions that may affect calcium metabolism, such as sarcoidosis or tuberculosis.

The side effects of Cholecalciferol 50,000 IU Capsule may include:

• Nausea and vomiting
• Diarrhea
• Constipation
• Dry mouth
• Metallic taste
• Fatigue and weakness
• Muscle or bone pain
• Increased calcium levels in the blood (hypercalcemia)

Following are the precautions and warnings for Cholecalciferol 50,000 IU Capsule:

• This medication should be used with caution in individuals with a history of hypercalcemia or conditions like sarcoidosis, where calcium levels may be elevated.
• Regular monitoring of calcium levels in the blood is necessary during prolonged treatment to prevent toxicity.
• Patients with kidney stones or a history of kidney disease should exercise caution and consult a doctor, as high doses of Vitamin D can increase the risk of kidney complications.
• Not recommended for individuals with hypervitaminosis D or those who have a high intake of Vitamin D from other sources.
• Cholecalciferol may interact with certain medications, including corticosteroids and anti-seizure drugs, so inform your doctor about all medications you are taking.
• Do not take more than the recommended dosage without medical supervision, as excessive Vitamin D can lead to serious health issues.
• Consult a healthcare professional if you have any underlying medical conditions or are taking other supplements to ensure safe and effective use.
• Keep out of reach of children, and store in a cool, dry place to maintain the integrity of the capsules.

Following are the drug interactions for Cholecalciferol 50,000 IU Capsule:

• Thiazide diuretics can decrease the excretion of vitamin D, leading to potential hypercalcemia.
• Cholestyramine and orlistat can reduce the absorption of vitamin D, decreasing its effectiveness.
• Phenytoin, phenobarbital, and rifampin may increase the metabolism of vitamin D, reducing its blood levels.
• Antacids containing aluminum or magnesium can hinder vitamin D absorption when taken simultaneously.
• Calcipotriene and other vitamin D analogs may increase the risk of hypercalcemia when used with cholecalciferol.
• Calcium supplements or calcium-containing medications can enhance the effects of vitamin D, requiring close monitoring of calcium levels.
• Vitamin D may interact with certain immune-suppressing drugs, such as ciclosporin, potentially affecting transplant outcomes.

Following are the food interactions for Cholecalciferol 50,000 IU Capsule:

• High-fat foods can enhance the absorption of Cholecalciferol, as vitamin D is fat-soluble. Consuming fatty fish, egg yolks, or dairy products alongside the capsule can improve its uptake.
• Vitamin D-fortified foods like milk, orange juice, and cereals can contribute to your daily vitamin D intake. Monitor your overall consumption to avoid excessive vitamin D levels.
• Calcium-rich foods like dairy products, leafy greens, and tofu can be beneficial, as vitamin D aids in calcium absorption. Ensure a balanced intake of both nutrients.
• Avoid excessive alcohol consumption, as it may interfere with vitamin D metabolism and impair calcium absorption, potentially leading to bone health issues.
• Grapefruit and grapefruit juice are generally safe to consume with Cholecalciferol, as there are no known direct interactions.
• Vitamin D supplements can interact with certain medications, so inform your healthcare provider about all the medicines you take.
• While not a food interaction, sunlight exposure can naturally provide vitamin D. Balancing sun exposure with supplementation is essential for maintaining optimal vitamin D levels.
• No significant food restrictions are associated with Cholecalciferol, but a balanced diet is recommended for overall health.

Cholecalciferol 50,000iu Capsules should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. It is crucial to keep the capsules in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. Avoid storing them in bathrooms or kitchens, as temperature fluctuations and humidity can impact their effectiveness. Always check the expiration date, and never use the capsules beyond this date. For disposal, do not flush or pour the medication down the drain; instead, consult your pharmacist or local waste management guidelines for safe and environmentally friendly disposal practices. Keep the capsules out of children's reach to prevent accidental consumption.

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Following are the quick tips for Cholecalciferol 50,000iu Capsule:

• Take the capsule as directed by your doctor, typically once a week or as prescribed.
• Swallow the capsule whole with a glass of water; do not crush or chew.
• Ensure you complete the full course of medication as prescribed.
• Avoid taking antacids or mineral oil within 2 hours of taking this medication.
• Maintain a consistent schedule for taking the capsule to ensure the best results.
• Inform your doctor if you have a history of kidney disease or are taking other medications.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.