Dmax (2000 IU) 60 Tablets

Cholecalciferol is converted into its active form, calcitriol, in the liver and kidneys. Calcitriol influences the secretion of parathyroid hormone (PTH), which plays a role in maintaining calcium levels by mobilizing calcium from bones and increasing calcium reabsorption in the kidneys. Vitamin D3 also helps maintain appropriate blood levels of calcium and phosphate, which are necessary for bone mineralization. It prevents excessive calcium loss from the bones and promotes the proper deposition of calcium in bone tissue. Calcitriol increases the intestinal absorption of calcium by enhancing the expression of calcium-binding proteins in the gut. This process ensures that sufficient calcium is available in the bloodstream for bone formation and maintenance.

Vitamin D Supplement

This supplement is used for:

• Vitamin D Deficiency
• Bone Health
• Calcium Absorption
• Osteoporosis Prevention

Cholecalciferol 2000IU dosage recommendations are:

• Immune system / Bone health - Once daily

In case of overdose, discontinue use and seek medical attention. Symptoms may include hypercalcemia, nausea, and vomiting.

Take the missed dose as soon as you remember. If it’s almost time for the next dose, skip the missed dose. Do not double up.

Take tablet with a meal, preferably at the same time each day. Follow dosage instructions provided by your healthcare provider.

Calcium + Cholecalciferol combination should not be used in the following situations:

• Severe hypercalcemia
• Kidney stones
• Allergy to any of the ingredients
• Severe kidney disease
• Parathyroid disorders

Unraveling the side effects lurking behind this drug product are the following:

• Constipation
• Nausea
• Stomach upset
• Allergic reactions

Patients should be aware of the following precautions and warnings when using cholecalciferol (Vitamin D3):

• Use with caution if you have hypercalcemia, hyperphosphatemia, or a history of kidney stones, as cholecalciferol can increase blood calcium and phosphate levels, potentially worsening these conditions. Regular monitoring of blood calcium and phosphate levels is recommended.
• Patients with renal insufficiency or cardiovascular disease should use cholecalciferol carefully, as it may impact calcium metabolism and cardiovascular health.
• Use with caution in individuals with malabsorption syndromes or gastrointestinal disorders, as these conditions can affect Vitamin D absorption.
• Monitor for interactions with other medications that affect calcium or phosphorus metabolism, such as diuretics or corticosteroids.
• Avoid excessive intake of Vitamin D from multiple sources to prevent toxicity, which can cause nausea, vomiting, weakness, and severe conditions like renal impairment.
• Pregnant or breastfeeding women should consult their healthcare provider before starting cholecalciferol to ensure appropriate dosing and safety.

Drug interactions with cholecalciferol include:

• Other vitamin D supplements (risk of vitamin D toxicity if taken in excess)
• Calcium supplements (may enhance the absorption of calcium but monitor for hypercalcemia)
• Magnesium supplements (high doses may affect calcium metabolism)
• Anticonvulsants (e.g., phenytoin, carbamazepine) (may decrease cholecalciferol levels)
• Glucocorticoids (e.g., prednisone) (may reduce the effectiveness of cholecalciferol)
• Thiazide diuretics (e.g., hydrochlorothiazide) (may increase the risk of hypercalcemia)
• Weight loss drugs (e.g., orlistat) (may reduce the absorption of fat-soluble vitamins including cholecalciferol)
• Antacids containing aluminum or magnesium (may interfere with absorption)

The food interactions that should be considered while using Cholecalciferol are:

• Avoid high-fat meals as they can impact the absorption of cholecalciferol
• Foods high in calcium should be consumed with caution as excessive calcium intake may affect absorption
• Foods high in fiber may reduce the absorption of cholecalciferol

Cholecalciferol should be stored properly to maintain its effectiveness. Store the product at a temperature between 15°C and 30°C in a cool, dry place, away from direct heat, light, and moisture. Ensure the container is tightly closed to prevent contamination. For safety purposes, keep Cholecalciferol out of reach of children and pets to avoid accidental ingestion. It is advisable to avoid storing the product in humid or warm areas, such as bathrooms or kitchens. If you have any questions or concerns about proper storage, consult your doctor or pharmacist for further guidance to ensure the product’s quality and safety.