Daonil (5mg) 60 Tablets

Daonil (5mg) 60 Tablets

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  • Manufacturer Sanofi-Aventis
  • Generic Name

    Glibenclamide 5mg

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Storage/Disposal
  • Description

    Glibenclamide is an oral medication used to treat type 2 diabetes mellitus. It belongs to the sulfonylureas class of drugs, which help regulate insulin levels in the body. Glibenclamide works by binding to specific receptors on beta-cells in the pancreas, stimulating the release of insulin. This action increases insulin availability in the bloodstream, helping to remove excess glucose and lower blood sugar levels. Not only does glibenclamide stimulate insulin release, but it also reduces insulin resistance in muscle and fat tissue. This reduction means these cells can more efficiently take up and use glucose. By increasing insulin availability and reducing resistance, glibenclamide helps to control blood sugar levels in those with type 2 diabetes.

  • Ingredients

    Glibenclamide 5mg

  • Drug Class

    Sulfonylurea

  • Dosage Form

    Tablet

  • Uses

    Glibenclamide is utilized for the following therapeutic indications:

    • Managing type 2 diabetes
    • Stimulating insulin secretion
    • Reducing blood glucose levels
    • Improving glycemic control
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Glibenclamide is a medication used to treat type 2 diabetes mellitus.
    • The typical initial dose is 5mg taken once daily, preferably before breakfast.
    • The dose may be increased up to a maximum of 15mg once daily if required, under medical supervision and careful monitoring of the patient's blood glucose levels.
  • In case of Overdose

    An overdose of Glibenclamide may cause low blood sugar levels or hypoglycemia. Low blood sugar can result in shakiness, lightheadedness, dizziness, confusion, fast heartbeat, cold sweats, seizure, and loss of consciousness. It is vital to seek medical attention if you suspect an overdose. Hypoglycemia can be treated by administering glucose or sugar to raise blood sugar levels. This can be done through ingestion or intravenous injection. If a specific drug overdose is suspected, an antidote such as flumazenil may be administered. However, this depends on the situation and is not the first treatment option. It's important to note that the order of treatment depends on the individual's health history, overdose circumstances, and resources available at the treatment facility.

  • Missed Dose

    It is important to avoid a double dose when you remember a missed dose to prevent hypoglycaemia or low blood sugar. If you miss a dose of glibenclamide, simply take the next dose at the regular time and continue with your normal routine. If you have any worries or miss multiple doses, contact your healthcare provider for assistance.

  • How To Use

    Before you start taking Glibenclamide, it is important to read the medication guide provided by your pharmacist. If you have any questions, ask your doctor or pharmacist. This medication should be taken regularly at the same time each day to maximize its effect. You may take it before or after a meal, but it should be swallowed whole and not crushed or chewed. The dosage is based on your medical condition and response to treatment, but should not exceed 15 mg per day if it is safe to do so. If you miss a dose, take it as soon as possible, but if it is almost time for your next dose, skip the missed dose and continue on your regular schedule. Do not take double the dose. Some side effects may occur such as dizziness, nausea, and vomiting. If they worsen or do not go away, consult your doctor or pharmacist. Store the medication away from heat and light at room temperature between 68-77°F (20-25°C). Keep it away from children and pets and follow the exact instructions given by your doctor or pharmacist.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • If you are allergic to Glibenclamide or any of the other ingredients in the medication, it is important to avoid taking this medication.
    • If you have diabetic ketoacidosis, which is a complication of diabetes that occurs when your body produces high levels of blood acids called ketones.
    • If you have severe kidney disease or renal impairment, your doctor may recommend a dosage adjustment or may suggest an alternative medication based on your condition. The same would apply to anyone with severe liver disease.
    • If you are pregnant or planning to become pregnant, it is important to inform your doctor before taking Glibenclamide.
    • If you have recently had or are planning to have surgery, it is important to inform your doctor or surgeon that you are taking Glibenclamide.
    • If you experience any severe side effects such as a hypersensitive reaction, low blood glucose levels (hypoglycemia), nausea, vomiting, headaches, or any allergic reaction, seek medical attention immediately.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Glycemic control may worsen, and a dose increase of insulin or oral hypoglycemic agents may be required.
    • Diabetic ketoacidosis may develop in acute conditions such as illness, stress, or fasting, especially in children or elderly patients.
    • Exposure to sunlight or ultraviolet light should be minimized during use, as glibenclamide can cause photosensitivity reactions.
    • Renal impairment should be noted as glibenclamide is excreted primarily by the kidneys; decreased renal function may require dose adjustment.
    • Overdose, and glucose levels should be monitored, and the patient should be observed closely for signs and symptoms of hypoglycemia or diabetic ketoacidosis.
    • With concurrent use of diamicron or other hypoglycemic agents, a decrease in blood glucose may be observed, and corresponding dosage adjustments may be required.
    • Risperidone and other drugs that can cause elevated blood levels of prolactin may enhance the antidiuretic effect of Diamicron and increase the risk of hypoglycemia.
    • Use with caution in patients with severe liver disease or alcoholism, as these conditions may increase the risk of hypoglycemia.
    • Use with caution in pregnant women, as well as women of childbearing potential not using effective contraception, as hypoglycemic agents can cause fetal harm.
  • Storage/Disposal

    Glibenclamide is a drug used to treat patients with type 2 diabetes mellitus and is to not be administered to patients with type 1 diabetes. It is an oral medication and must be kept in storage accordingly to ensure effectiveness. The medication should be stored in a temperature ranging from 15°C and 30°C (59°F and 86°F) and avoidance of heat, direct sunlight, or freezing temperatures to prevent medication degradation. Due to the nature of the drug, it is important to keep out of reach of children and pets to prevent accidental consumption. The shelf life of Glibenclamide is 3 years from the date of manufacture, however, it is recommended to discard unused or expired medication to prevent any harm. If you have any questions regarding the storage of Glibenclamide, it is recommended to consult with a physician, pharmacist, or medical provider for a more detailed guide.

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