D-Cap 40000 (40000IU) 10 Capsules

Cholecalciferol, also known as vitamin D3, has a specific mechanism of action in the body. When ingested, cholecalciferol undergoes two hydroxylation reactions to become its active form, calcitriol. The first hydroxylation occurs in the liver, converting cholecalciferol to 25-hydroxyvitamin D (calcifediol). Subsequently, the kidneys perform the second hydroxylation, transforming calcifediol into 1,25-dihydroxyvitamin D (calcitriol). Calcitriol exerts its physiological effects by binding to the vitamin D receptor (VDR) located in the nucleus of target cells. This binding triggers a cascade of events, including gene expression regulation, that influences calcium and phosphate metabolism. Specifically, it promotes calcium absorption in the intestines, enhances calcium reabsorption in the kidneys, and mobilizes calcium from bones, thereby playing a crucial role in maintaining calcium homeostasis and promoting bone health.

Cholecalciferol 40,000iu

Vitamin D Supplement

Capsule

The following are the uses of Cholecalciferol 40,000iu Capsule:

• Used for treating Vitamin D deficiency, ensuring proper bone development and preventing conditions like rickets.
• Used for managing osteoporosis, aiding in calcium absorption for stronger bones.
• Used to support immune function, as Vitamin D plays a crucial role in immune system regulation.
• Used to reduce the risk of respiratory infections, particularly in individuals with Vitamin D deficiency.
• Used for maintaining overall health, as it helps regulate muscle, nerve, and immune system functions.
• Used in the treatment of psoriasis, a skin condition, by controlling cell turnover and reducing inflammation.
• Used to support cardiovascular health, as Vitamin D deficiency is linked to increased cardiovascular risks.
• Used to enhance mood and cognitive function, as Vitamin D receptors are present in brain regions linked to depression and cognitive performance.

In the case of an overdose of Cholecalciferol 40,000 IU capsules, symptoms may include nausea, vomiting, constipation, loss of appetite, weakness, and kidney problems. An excess of vitamin D can lead to hypercalcemia, causing abnormal heart rhythms, confusion, and bone pain. Seek medical advice promptly if you suspect an overdose, as treatment may involve supportive care and monitoring of calcium and vitamin D levels to prevent further complications.

In the case of a missed dose of Cholecalciferol 40,000 IU Capsule, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have missed multiple doses, consult your healthcare provider for advice on how to safely resume your supplementation and ensure you receive the correct amount of vitamin D.

To take Cholecalciferol 40,000 IU capsules, swallow the capsule whole with a glass of water, preferably with a meal or as directed by your healthcare professional, once a week or as instructed by your doctor.

Following are the conditions when Cholecalciferol 40,000iu Capsule should not be taken:

• Should not be taken by individuals with a known hypersensitivity or allergy to Cholecalciferol or any of its ingredients.
• Contraindicated in patients with hypervitaminosis D (excessive levels of vitamin D in the body).
• Not recommended for individuals with high blood calcium levels (hypercalcemia) or those with conditions causing high calcium levels, such as sarcoidosis or Williams syndrome.
• Avoid in patients with kidney stones or conditions that increase the risk of kidney stones, such as hypercalciuria (high calcium levels in urine).
• Should not be used in patients with conditions causing calcium to be deposited in soft tissues, such as idiopathic hypercalciuria.
• Contraindicated in patients with conditions that impair the body's ability to absorb or utilize vitamin D, such as malabsorption syndromes or certain liver diseases.

The side effects of Cholecalciferol 40,000 IU Capsule may include:

• Nausea and vomiting.
• Diarrhea or constipation.
• Loss of appetite.
• Fatigue and weakness.
• Dry mouth.
• Metallic taste.
• Muscle or joint pain.
• Increased thirst and frequent urination.

Following are the precautions and warnings for Cholecalciferol 40,000 IU Capsule:

• Do not exceed the recommended dosage, as high doses of Vitamin D can lead to hypervitaminosis D and potential harm to the body.
• Individuals with a history of hypercalcemia or conditions that increase calcium levels should use this medication with caution and under medical supervision.
• Patients with kidney disease or conditions affecting kidney function should be monitored for changes in calcium levels while taking this medication.
• Cholecalciferol may interact with certain medications; inform your doctor about all the medicines you are currently taking.
• This medication may not be suitable for individuals with a history of kidney stones or those who have conditions that increase the risk of developing kidney stones.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as Vitamin D requirements may vary during these periods.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
• If you have any underlying medical conditions or are taking other supplements, consult your healthcare provider before starting this medication.

Following are the drug interactions for Cholecalciferol 40,000 IU Capsule:

• Anticonvulsants (e.g., phenobarbital, phenytoin) may reduce vitamin D effectiveness, requiring higher vitamin D doses.
• Cholestyramine and colestipol can decrease vitamin D absorption, potentially requiring dose adjustments.
• Thiazide diuretics, such as hydrochlorothiazide, can elevate calcium levels when used with vitamin D, necessitating monitoring.
• Calcium channel blockers like verapamil and diltiazem may increase the risk of hypercalcemia when combined with vitamin D.
• Orlistat can reduce vitamin D absorption, possibly requiring supplementation.
• Aluminum-containing antacids may decrease vitamin D absorption, affecting bone metabolism.
• Corticosteroids like prednisone may increase vitamin D requirements due to altered metabolism.

Following are the food interactions for Cholecalciferol 40,000 IU Capsule:

• Consuming foods rich in vitamin D, such as fatty fish (salmon, mackerel), egg yolks, and fortified dairy products, alongside the capsule may lead to excessive vitamin D intake, causing potential hypervitaminosis D.
• Avoid high-fat meals as they may decrease the absorption of Cholecalciferol, reducing its effectiveness.
• Grapefruit and grapefruit juice should be limited as they can interfere with vitamin D metabolism, potentially altering its effects.
• Avoid excessive consumption of calcium-rich foods like dairy products and leafy greens, as high vitamin D levels can increase calcium absorption, leading to hypercalcemia.
• Alcohol should be consumed in moderation as it may impair the liver's ability to metabolize vitamin D, affecting its overall effectiveness.
• Vitamin D-fortified foods and supplements should be monitored to prevent excessive intake, as too much vitamin D can lead to toxicity.
• Maintain a balanced diet, ensuring you get essential nutrients from various sources, as relying solely on supplements may not provide all necessary vitamins and minerals.

Cholecalciferol 40,000iu Capsules should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. Keep the capsules in their original packaging, tightly sealed, to maintain their integrity and prevent exposure to environmental factors. It is crucial not to store them in bathrooms or near heat sources, as temperature fluctuations can impact their effectiveness. Dispose of any unused or expired capsules responsibly; do not flush them or pour them down the drain. Consult your pharmacist or healthcare provider for guidance on proper disposal methods, and keep all medications out of children's reach to prevent accidental consumption. Adhering to these storage and disposal practices ensures the safety and efficacy of Cholecalciferol capsules.

Following are the quick tips for Cholecalciferol 40,000iu Capsule:

• Consult your doctor before taking this medication, especially if you have a history of kidney stones or kidney disease.
• Take the capsule as directed by your healthcare provider; do not exceed the prescribed dosage.
• Consume the capsule with a meal to enhance vitamin D absorption.
• Maintain a consistent schedule for taking the medication for best results.
• Ensure you stay well-hydrated while taking this medication.
• Avoid taking other vitamin D supplements or calcium supplements without medical advice.
• Regularly monitor your vitamin D levels as advised by your doctor.
• Store the capsules in a cool, dry place, away from direct sunlight.