DEKOF TAB

Pseudoephedrine, Codeine, and Triprolidine are combined in a tablet form to provide relief from various symptoms. Pseudoephedrine is a sympathomimetic amine that acts as a decongestant by constricting blood vessels in the nasal passages, reducing swelling and congestion. It primarily targets alpha-adrenergic receptors in the respiratory tract. Codeine, an opioid analgesic, binds to opioid receptors in the central nervous system, altering the perception of pain and providing cough suppression. It also induces a sense of well-being and relaxation. Triprolidine, an antihistamine, blocks histamine receptors, specifically H1 receptors, thereby reducing allergic symptoms such as sneezing, itching, and runny nose. By blocking the histamine-induced dilation of blood vessels, it helps alleviate congestion. This combination medication works synergistically to provide relief from symptoms associated with respiratory conditions, including congestion, cough, and allergic reactions.

Decongestant and Antihistamine

Tablet

The following are the uses of Pseudoephedrine, Codeine, Triprolidine Tablet:

• Used for temporarily relieving symptoms of sinus pressure, congestion, runny nose, sneezing, and coughing due to the common cold, upper respiratory infections, or allergies.
• Used to provide relief from a persistent, dry cough.
• Used to reduce inflammation and congestion in the nasal passages and sinuses.
• Used to alleviate symptoms of hay fever and other allergic reactions.
• Used for managing mild to moderate pain and discomfort.
• Used to suppress coughing and provide comfort for patients with a persistent cough.
• Used as a decongestant to improve breathing by reducing swelling in the nasal passages.

In the case of an overdose of Pseudoephedrine, Codeine, and Triprolidine Tablet, the effects can vary depending on the individual and the amount ingested. Common symptoms may include increased heart rate, dizziness, severe drowsiness, and difficulty breathing. In severe cases, it could lead to seizures, loss of consciousness, and even respiratory failure. Prompt medical attention is necessary, and healthcare professionals should be informed about the specific substances involved to provide appropriate treatment.

In the case of a missed dose of Pseudoephedrine, Codeine, and Triprolidine Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication.

To take the Pseudoephedrine, Codeine, Triprolidine Tablet, swallow the tablet whole with a full glass of water, as directed by your healthcare provider, typically every 4 to 6 hours as needed for congestion and cough relief, but not exceeding the maximum daily dosage specified in the instructions.

Following are the conditions/situations when Pseudoephedrine, Codeine, Triprolidine Tablet should not be used:

• Avoid use in individuals with a known allergy or hypersensitivity to Pseudoephedrine, Codeine, Triprolidine, or any other decongestants, opioids, or antihistamines.
• Not suitable for patients with narrow-angle glaucoma or increased intraocular pressure.
• Contraindicated in patients with severe high blood pressure, severe heart disease, or those who have recently had a heart attack.
• Should not be used in individuals with severe liver or kidney impairment.
• Avoid use in patients with difficulty urinating due to an enlarged prostate or any other urinary retention issues.
• Not recommended for children below 12 years of age.
• Do not use if you are currently taking or have recently taken monoamine oxidase inhibitors (MAOIs).
• Should not be used during breastfeeding, as Codeine and Pseudoephedrine can pass into breast milk.
• Contraindicated in patients with respiratory conditions such as asthma, severe chronic obstructive pulmonary disease (COPD), or those with a history of breathing problems.
• Avoid use in individuals with a history of seizures or conditions that increase the risk of seizures.

The side effects of Pseudoephedrine, Codeine, Triprolidine Tablet may include:

• Dizziness or lightheadedness
• Nausea and vomiting
• Dry mouth
• Constipation
• Drowsiness or sedation
• Blurred vision
• Restlessness or agitation
• Difficulty urinating

Following are the precautions and warnings for Pseudoephedrine, Codeine, Triprolidine Tablet:

• Avoid use if you are allergic to any of the active ingredients or similar medications.
• This medication may cause drowsiness or dizziness, so refrain from driving or operating heavy machinery until you know how it affects you.
• Inform your doctor about any medical conditions, especially liver, kidney, or respiratory issues, before taking this medication.
• Do not consume alcohol while using this medication as it may increase the risk of side effects.
• Pregnant or breastfeeding women should consult a healthcare professional before use, as it may have potential risks.
• Keep this medication out of reach of children and pets. Store it in a secure place, away from direct sunlight and moisture.
• Do not exceed the recommended dosage and duration of use without consulting your healthcare provider.

Following are the drug interactions for Pseudoephedrine, Codeine, Triprolidine Tablet:

• Monoamine oxidase inhibitors (MAOIs) should be avoided as they can cause severe high blood pressure.
• May interact with other central nervous system depressants like benzodiazepines, increasing sedation and respiratory depression.
• Alcohol consumption can enhance the sedative effects of codeine, leading to impaired motor skills and cognitive function.
• Tricyclic antidepressants and SSRIs may increase the risk of side effects when combined with triprolidine.
• Antihistamines and anticholinergic drugs can lead to increased side effects and potential overdose.
• Drugs that increase serotonin levels, such as certain antidepressants, may cause serotonin syndrome when taken with codeine.
• Medications that affect the liver's CYP450 enzyme system may influence the metabolism of these drugs.

Following are the food interactions for Pseudoephedrine, Codeine, Triprolidine Tablet:

• Grapefruit and grapefruit juice should be avoided as they may interfere with the metabolism of Codeine, potentially leading to increased side effects and prolonged drug effects.
• Alcohol should be consumed with caution as it can enhance the sedative effects of Codeine, increasing the risk of dizziness, drowsiness, and impaired coordination.
• Caffeine-containing beverages like coffee and energy drinks should be limited as Pseudoephedrine may already stimulate the central nervous system, and combining it with caffeine can lead to increased heart rate, nervousness, and insomnia.
• Dairy products may potentially decrease the absorption of Triprolidine, so it is advisable to separate their consumption by a few hours.
• Consuming high-fat meals may slightly delay the absorption of Codeine, but it generally does not significantly affect its overall effectiveness.
• Spicy foods may increase nasal congestion and discomfort, so it is best to limit their intake while using Pseudoephedrine.
• Well-balanced meals are essential to maintain overall health and support the body's response to medications.
• Always follow the advice of your healthcare provider regarding dietary considerations and medication management.

Pseudoephedrine, Codeine, Triprolidine Tablets should be stored in a secure and dry location, preferably in a medicine cabinet, at room temperature, ensuring it remains protected from direct sunlight, heat, and moisture. It is crucial to keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. When disposing of unused or expired tablets, it is important to follow local guidelines and regulations. Do not flush them down the toilet or dispose of them in household trash. Instead, utilize medication take-back programs or consult your pharmacist for guidance on safe disposal methods, ensuring these substances do not contaminate the environment or pose a risk to others. Keep the medication out of children's reach to prevent accidental ingestion.

Following are the quick tips for Pseudoephedrine, Codeine, Triprolidine Tablet:

• Consult a doctor or pharmacist for personalized advice before taking this medication.
• Ensure you understand the potential side effects and interactions.
• Take the tablet as directed by your healthcare provider.
• Do not exceed the recommended dosage without medical advice.
• Avoid alcohol consumption while taking this medication.
• Store the medication in a cool, dry place, away from direct sunlight.
• Inform your doctor if you have any pre-existing medical conditions or allergies.
• Do not share your medication with others, even if their symptoms are similar.