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Delosit (5mg) 10 Tablets
- Manufacturer Cell Laboratories (Pvt.) Ltd.
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Generic Name
Desloratadine
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Healthwire Pharmacy Ratings & Reviews (1500+)
Product Information
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Description
Desloratadine is a second generation tricyclic histamine receptor antagonist. It is an active descarboethoxy metabolite of loratadine. Desloratadine is a non-sedating, long-acting acting histamine antagonist with selective peripheral H1-receptor antagonist activity. Desloratadine after oral administration; selectively blocks peripheral histamine H1-receptors because it does not enter the central nervous system; that's why it does not cause drowsiness.
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Ingredients
Desloratadine
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Drug Class
Antihistamine
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Dosage Form
Tablet
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Uses
Used to treat symptoms of allergy like; runny nose, watery eyes, sneezing. Aids in relief of nasal and non-nasal symptoms of seasonal and perennial Allergic Rhinitis. Treats chronic spontaneous Urticaria and Hives.
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Dosage
Dose must be taken according to doctor’s advice only; doses given below are suggested as supportive literature for better understanding in some areas of requirements. For adults and children of age above 12 years: 5mg daily.
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In case of Overdose
Symptomatic and supportive measures should be taken after overdose. Dose of 250mg/kg or above is lethal.
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Missed Dose
In case you missed any dose, take the next dose as soon as you remember, but don't double your next dose to compensate for the missed one.
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How To Use
Take orally after a meal or as your doctor prescribed.
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When Not to Use
Should not be given to patients with hypersensitivity to loratadine or desloratadine or any of its component mixture.
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Side Effects
Unraveling the side effects lurking behind this product are the following:
• Tachycardia
• Palpitation
• Hypersensitivity reactions
• Psychomotor hyperactivity
• Seizure
• Elevated liver enzymes
• Hepatitis (rarely)
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Precautions & Warnings
Dose should be adjusted in patients with liver or kidney problems.
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Drug Interactions
The drug interactions with desloratadine include:
- CYP3A4 Inhibitors (e.g., ketoconazole) – Can increase desloratadine levels.
- CYP2D6 Inhibitors (e.g., fluoxetine) – May increase desloratadine levels.
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Food Interaction
Its efficacy is not affected by food.
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Storage/Disposal
Store below 25°C. Protect from sunlight, heat and moisture.
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