Dementio ER (12mg) 30 Tablets

Dementio ER (12mg) 30 Tablets

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  • Manufacturer GENETICS PHARMACEUTICALS (PVT.) LTD.
  • Generic Name

    Galantamine HBr 12mg

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Galantamine HBr 12mg Tablet primarily exerts its therapeutic effects through the reversible inhibition of acetylcholinesterase, an enzyme responsible for the breakdown of acetylcholine in the brain. By inhibiting acetylcholinesterase, galantamine increases the concentration of acetylcholine, a neurotransmitter involved in memory, learning, and cognitive functions. This mechanism is crucial in the treatment of cognitive impairments associated with conditions such as Alzheimer's disease. Galantamine also demonstrates allosteric modulation of nicotinic acetylcholine receptors, enhancing their sensitivity to acetylcholine and promoting cholinergic transmission, which further contributes to its cognitive-enhancing effects.

  • Ingredients

    Galantamine HBr 12mg

  • Drug Class

    Acetylcholinesterase inhibitor.

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Galantamine HBr 12mg Tablet:

    • Used for enhancing cognitive function in Alzheimer's disease, improving memory, attention, and overall cognitive abilities.
    • Used to slow down the progression of dementia symptoms, allowing individuals to maintain independence for a longer period.
    • Used for the treatment of mild to moderate Alzheimer's disease, offering symptom management and potential stabilization of cognitive decline.
    • Used for managing cognitive impairment related to vascular dementia, helping improve blood flow to the brain and enhance cognitive functions.
    • Used as a cholinesterase inhibitor, increasing the levels of acetylcholine, a neurotransmitter essential for memory and learning.
    • Used to reduce the severity of cognitive impairment, enabling individuals to engage in daily activities with improved focus and mental clarity.
    • Used to delay the need for full-time caregiving, providing patients with a better quality of life and increased independence.
    • Used in combination with other therapies, such as cognitive stimulation and behavioral interventions, to maximize the overall treatment outcomes.
  • In case of Overdose

    In the case of an overdose of Galantamine HBr 12mg Tablets, individuals may experience severe side effects. Symptoms can include nausea, vomiting, diarrhea, abdominal pain, dizziness, and in extreme cases, seizures or a significant drop in blood pressure. It is crucial to seek medical assistance promptly if an overdose is suspected. Quick action can help manage the symptoms and prevent potential complications, ensuring the best possible outcome for the individual's health.

  • Missed Dose

    In the case of a missed dose of Galantamine HBr 12mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one. It is generally recommended not to double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare provider for guidance on how to adjust your dosing schedule safely. They will advise you on how to proceed and ensure you maintain the medication's effectiveness.

  • How To Use

    To take Galantamine HBr 12mg Tablet, swallow the tablet whole with a full glass of water, preferably in the morning or as directed by your doctor, and follow the prescribed dosage instructions for the duration of your treatment.

  • When Not to Use

    Following are the conditions/situations when Galantamine HBr 12mg Tablet should not be taken:

    • Must not be used in individuals with a known allergy to Galantamine or any piperidine derivatives.
    • Not suitable for individuals with certain heart conditions, such as sick sinus syndrome or AV block.
    • Should not be used in patients with severe liver or kidney disease.
    • Contraindicated in individuals with a history of seizures or epilepsy.
    • Not recommended for those with gastrointestinal obstruction or conditions that slow the digestive system.
    • Avoid in patients with acute asthma or chronic obstructive pulmonary disease (COPD).
    • Do not use in individuals with urinary tract obstruction.
  • Side Effects

    The side effects of Galantamine HBr 12mg Tablet may include:

    • Nausea and vomiting
    • Diarrhea
    • Loss of appetite
    • Weight loss
    • Dizziness
    • Headache
    • Slow heartbeat (bradycardia)
    • Increased sweating
  • Precautions & Warnings

    Following are the precautions and warnings for Galantamine HBr 12mg Tablet:

    • Not suitable for individuals with a known allergy to galantamine or any of its excipients.
    • Patients with a history of gastrointestinal disorders should exercise caution, as the medication can aggravate these conditions.
    • Galantamine may cause dizziness or drowsiness; patients should avoid driving or operating heavy machinery until they know how the medication affects them.
    • Caution is advised for patients with a history of heart problems, as galantamine can affect heart rate and rhythm.
    • Regular monitoring of liver function is recommended, especially in patients with pre-existing liver conditions.
    • Not recommended for use in children and adolescents under 18 years of age unless prescribed by a specialist.
    • Elderly patients may require lower doses as they are more susceptible to side effects.
    • Always inform your healthcare provider about all medications you are currently taking to avoid potential drug interactions.
  • Drug Interactions

    Following are the drug interactions for Galantamine HBr 12mg Tablet:

    • Concomitant use with cholinergic agonists, such as succinylcholine, can lead to prolonged muscle paralysis.
    • Galantamine may increase the effects of neuromuscular blocking agents, requiring close monitoring.
    • Drugs that inhibit cytochrome P450 enzymes (e.g., CYP3A4 and CYP2D6 inhibitors) can raise galantamine levels, necessitating dosage adjustments.
    • Co-administration with non-depolarizing muscle relaxants may enhance their effects, requiring dosage adjustments.
    • The use of anticholinergic medications may counteract the effects of Galantamine, reducing its efficacy.
    • Caution is advised when combining Galantamine with other centrally acting drugs, as it may affect their pharmacokinetics.
    • Galantamine can increase the risk of bradycardia when used with medications that slow heart rate, such as beta-blockers.
  • Food Interactions

    Following are the food interactions for Galantamine HBr 12mg Tablet:

    • Grapefruit and grapefruit juice consumption should be avoided as they can increase the drug's bioavailability and potentially lead to adverse effects.
    • Alcohol intake should be minimized as it can increase the risk of dizziness, drowsiness, and other side effects associated with the medication.
    • Avoid caffeine-rich beverages like coffee and energy drinks as they may counteract the therapeutic effects of Galantamine.
    • Consuming high-fat meals may delay the absorption of Galantamine, affecting its onset of action.
    • Avoid consuming large amounts of chocolate, as it contains compounds that can inhibit the enzyme responsible for metabolizing Galantamine.
    • Some herbal teas, especially those containing St. John's Wort, may interact with Galantamine and should be consumed with caution.
    • Always inform your healthcare provider about your dietary habits to ensure the safe and effective use of Galantamine HBr tablets.
    • No significant food restrictions are typically necessary, but individual responses may vary, so consult your doctor for personalized advice.
  • Storage/Disposal

    Galantamine HBr 12mg Tablets should be stored in a secure and dry location, away from direct sunlight and moisture. Maintain the tablets in their original packaging, ensuring the container is tightly sealed to prevent exposure to air and humidity. It is crucial not to store them in bathrooms or near heat-emitting appliances to preserve their integrity. Regularly check the expiration date, and if the tablets are no longer needed or have expired, proper disposal is essential. Avoid flushing them down the toilet or sink; instead, consult your pharmacist or local waste management guidelines for safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

  • Quick Tips, if any

    Following are the quick tips for Galantamine HBr 12mg Tablet:

    • Consult your doctor before starting the medication for personalized advice.
    • Take the tablet as directed by your physician, typically once or twice daily.
    • Maintain a consistent schedule for taking the medication for maximum benefits.
    • Swallow the tablet whole with a full glass of water for easy swallowing.
    • Avoid crushing, chewing, or breaking the tablet unless advised by your doctor.
    • Do not abruptly stop the medication; consult your doctor for dose adjustments.
    • Store the tablets at room temperature, away from moisture and light.

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