DENTINOX IMP TEETHING GEL

Lidocaine gel is a local anesthetic that primarily works by blocking voltage-gated sodium channels in nerve cell membranes. When applied topically, lidocaine molecules penetrate the skin and reach the underlying nerve fibers. Once there, they interfere with the electrical signaling process by binding to specific receptor sites on the sodium channels. This binding inhibits the rapid influx of sodium ions into the nerve cells, which is essential for generating and propagating nerve impulses. By blocking the sodium channels, lidocaine prevents the initiation and transmission of pain signals, leading to a temporary numbing effect in the area where it is applied. This mechanism of action allows lidocaine gel to provide effective local anesthesia, making it useful for various medical procedures and conditions where pain relief is required.

Lidocaine

Local anesthetic

Gel

The following are the uses of Lidocaine Gel:

• Used for numbing pain and providing temporary relief from discomfort.
• Used for minor skin procedures and injections to reduce pain.
• Used for treating mouth ulcers and oral sores, easing pain during eating and talking.
• Used for relieving sunburn and minor skin burns to reduce pain and itching.
• Used for certain dental procedures to numb the gums or mouth.
• Used for post-operative pain management to reduce discomfort.
• Used for soothing irritated or inflamed skin caused by conditions like eczema or insect bites.

In the case of an overdose of Lidocaine Gel, it is important to recognize the potential symptoms and take appropriate action. Overuse can lead to increased numbness and tingling sensations, dizziness, and in severe cases, seizures or cardiac arrest. If an overdose is suspected, promptly seek medical assistance and provide healthcare professionals with detailed information about the amount of gel applied and any observed symptoms. Quick intervention is vital to prevent serious health complications.

In the case of a missed dose of Lidocaine Gel, it is important to apply the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra gel to make up for a missed dose, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely adjust your dosing schedule. It is generally recommended to follow the prescribed application frequency to ensure the medication's effectiveness.

To apply Lidocaine Gel, clean and dry the affected area, then gently squeeze a small amount of the gel onto your fingertips and apply a thin layer directly to the skin, rubbing it in gently until absorbed, ensuring not to apply on open wounds or mucous membranes.

Here are the conditions and situations when Lidocaine Gel should not be used:

• Avoid using Lidocaine Gel if you have a known allergy or sensitivity to local anesthetics, especially to Lidocaine or any other related medications.
• Do not use it on or near mucous membranes, such as inside the mouth, nose, or eyes, unless specifically directed by a healthcare professional.
• Contraindicated in patients with a history of severe or systemic allergic reactions to any local anesthetic agent of the amide type.
• Should not be used on open wounds, infected areas, or deep puncture wounds without medical supervision.
• Avoid using Lidocaine Gel on skin conditions like eczema, dermatitis, or severe skin irritation in the area to be treated.
• Not recommended for infants or children without proper medical advice and supervision.
• Do not use it on skin areas with impaired sensation or reduced skin integrity.
• Avoid using it on skin that is severely broken or burned.
• Contraindicated in patients with a known metabolic disorder called pseudocholinesterase deficiency.
• Do not use Lidocaine Gel on skin areas with a severe lack of blood circulation (ischemia).

The side effects of Lidocaine Gel may include:

• Skin irritation or redness at the application site
• Burning or stinging sensation
• Itching
• Numbness or tingling
• Swelling or inflammation
• Allergic reactions (skin rash, hives)
• Dizziness or lightheadedness
• Nausea and vomiting

Following are the precautions and warnings for Lidocaine Gel:

• Avoid contact with eyes and mucous membranes as it may cause irritation or damage.
• Do not apply to open wounds, broken skin, or infected areas.
• Wash your hands thoroughly before and after application to prevent accidental transfer to other body parts or individuals.
• Avoid using occlusive dressings or bandages over the gel unless directed by a healthcare professional.
• Lidocaine Gel should not be used in individuals with a known allergy to local anesthetics or any of its ingredients.
• It should be used with caution in patients with severe liver disease as it is metabolized by the liver.
• Consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding, as the effects of Lidocaine Gel on fetal development and nursing infants are not fully established.

Following are the drug interactions for Lidocaine Gel:

• Lidocaine may interact with other local anesthetics or Class 1 antiarrhythmic medications, potentially enhancing their effects and leading to increased risk of adverse effects.
• Use with other sodium channel blockers can increase the risk of cardiac toxicity.
• It may reduce the effectiveness of certain drugs by decreasing their absorption, such as imiquimod and diclofenac.
• Lidocaine can increase the blood levels of some drugs metabolized by the liver, including phenytoin and mexiletine.
• The gel can enhance the anticoagulant effect of warfarin, requiring close monitoring of INR (International Normalized Ratio).
• Lidocaine may interfere with the metabolism of drugs that use the CYP3A4 enzyme, such as certain benzodiazepines and statins.
• Caution is advised when using Lidocaine with other medications that affect the cardiovascular system, as it may cause additive effects on heart rate and blood pressure.

Following are the food interactions for Lidocaine Gel:

• Avoid consuming excessive amounts of caffeine-rich foods like coffee, tea, or energy drinks while using Lidocaine Gel, as it may increase the risk of side effects related to the central nervous system.
• Alcoholic beverages should be used with caution. Lidocaine may increase the effects of alcohol, leading to increased dizziness and drowsiness.
• Grapefruit and grapefruit juice should be consumed in moderation as they can affect the metabolism of some medications, potentially altering Lidocaine's effectiveness.
• Avoid spicy foods as they may cause skin irritation or increase sensitivity in the treated area.
• Dairy products like milk, cheese, and yogurt are generally safe, but in some individuals, they might increase mucus production and throat irritation, especially if you have a respiratory condition.
• Sugary foods and beverages should be limited as they can promote bacterial growth and potentially delay wound healing in the oral cavity.
• Avoid hot and acidic foods, such as citrus fruits, tomatoes, and spicy dishes, as they can cause discomfort and irritation in the treated area.
• Oily and fatty foods may not directly interact with Lidocaine Gel, but they can impact overall health and healing, potentially affecting the treatment area.

Lidocaine Gel should be stored at room temperature, preferably between 68°F and 77°F (20°C and 25°C), in its original container with the cap tightly secured. It is important to keep the gel away from excessive heat, direct sunlight, and moisture. Do not freeze the gel as it may affect its consistency and effectiveness. Always check the expiration date on the tube before each application, and discard any expired or unused gel according to local regulations and guidelines. Proper disposal ensures that the medication does not harm the environment or pose a risk to others. Keep the gel out of the sight and reach of children and pets to prevent accidental exposure.

Following are the quick tips for Lidocaine Gel:

• Wash your hands before and after applying the gel to maintain hygiene.
• Apply a thin layer of the gel to the affected area as directed by your doctor.
• Gently rub the gel into the skin until it is absorbed, ensuring even coverage.
• Avoid applying the gel to open wounds, eyes, or mucous membranes.
• Do not cover the treated area with airtight dressings or bandages.
• Wash your hands thoroughly after application, especially before touching your eyes or face.
• Store the gel at room temperature, away from direct sunlight and moisture.