Depricap (20mg/5ml) 60ml Oral Solution

Fluoxetine 20mg/5ml Solution primarily exerts its therapeutic effects by selectively inhibiting the reuptake of serotonin (5-hydroxytryptamine, 5-HT) in the brain. Serotonin is a neurotransmitter that plays a crucial role in regulating mood, emotions, and various physiological processes. By blocking the reuptake of serotonin, fluoxetine increases its availability in the synaptic cleft, allowing for enhanced serotonin signaling. This mechanism is believed to contribute to the antidepressant and anxiolytic effects of the medication. Fluoxetine's selectivity for the serotonin transporter helps minimize its impact on other neurotransmitter systems, thereby reducing the likelihood of certain side effects associated with non-selective reuptake inhibitors. Over time, this modulation of serotonin levels is thought to lead to adaptive changes in neuronal circuits, resulting in the alleviation of depressive symptoms and the promotion of emotional well-being.

Fluoxetine 20mg/5ml

Antidepressant, SSRI (Selective Serotonin Reuptake Inhibitor)

Solution

The following are the uses of Fluoxetine 20mg/5ml Solution:

• Used for treating major depressive disorder in adults, helping to alleviate symptoms like persistent sadness and loss of interest.
• Used for managing obsessive-compulsive disorder (OCD) by reducing intrusive thoughts and compulsive behaviors.
• Used for alleviating symptoms of bulimia nervosa, such as binge eating and purging.
• Used for addressing severe symptoms of premenstrual dysphoric disorder (PMDD) in women.
• Used for treating panic disorder by reducing the frequency and intensity of panic attacks.
• Used for managing certain eating disorders, assisting in regulating eating behaviors.
• Used for improving mood and overall well-being in individuals with persistent depressive disorder.

In the case of an overdose of Fluoxetine 20mg/5ml Solution, the severity of symptoms can vary depending on the amount ingested. Common signs may include nausea, vomiting, seizures, rapid heartbeat, and changes in mental status. Prompt medical intervention is necessary to manage these symptoms effectively. Treatment may involve gastric lavage, administration of activated charcoal, and close monitoring of vital signs and cardiac function. Quick action can help mitigate the potential risks associated with such an overdose.

In the case of a missed dose of Fluoxetine 20mg/5ml Solution, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss several doses, contact your healthcare provider for guidance on how to safely resume your medication and maintain its effectiveness.

To administer Fluoxetine 20mg/5ml Solution, shake the bottle well, then use a measuring device like a syringe or dosing spoon to measure the prescribed amount, and take it orally once daily as directed by your healthcare professional, either with or without food.

Here are the conditions or situations when Fluoxetine 20mg/5ml Solution should not be used:

• Must not be taken by individuals who are allergic to Fluoxetine or similar antidepressants, such as Prozac.
• Not suitable for individuals with a history of liver disease or severe kidney problems.
• Contraindicated in patients with a history of seizures or epilepsy.
• Should not be used by individuals taking other medications that may interact adversely, such as MAO inhibitors.
• Avoid in patients with a history of bleeding disorders or who are currently taking blood thinners.
• Not recommended for those with a history of glaucoma.
• Must not be used in patients with a history of serotonin syndrome.
• Contraindicated during the last trimester of pregnancy, as it may cause complications.
• Should not be given to children and adolescents under 18 years of age without medical advice.

The side effects of Fluoxetine 20mg/5ml Solution may include:

• Nausea and vomiting
• Diarrhea or constipation
• Headaches
• Dizziness or lightheadedness
• Insomnia or sleep disturbances
• Fatigue and weakness
• Skin rashes or itching
• Restlessness or agitation

Following are the precautions and warnings for Fluoxetine 20mg/5ml Solution:

• Not suitable for individuals with a known allergy to Fluoxetine or related antidepressants.
• Requires caution in patients with a history of liver or kidney problems, as dosage adjustments may be necessary.
• Should be used with caution in individuals with a history of seizures or epilepsy, as it may lower the seizure threshold.
• May increase the risk of bleeding, so patients with bleeding disorders or those taking anticoagulant medications should be monitored closely.
• Not recommended for use in children and adolescents under 18 years of age unless prescribed by a healthcare professional.
• May cause drowsiness and dizziness; patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Pregnant and breastfeeding women should consult their doctor before taking Fluoxetine, as it may have potential risks for the fetus and infant.
• Discontinuation of Fluoxetine should be gradual to minimize withdrawal symptoms; do not stop abruptly.

Following are the drug interactions for Fluoxetine 20mg/5ml Solution:

• Serotonin syndrome risk is increased with other serotonergic drugs (SSRIs, SNRIs, triptans, certain pain medications).
• Contraindicated with monoamine oxidase inhibitors (MAOIs), can lead to severe reactions including serotonin syndrome.
• May interact with anticoagulants like warfarin, necessitating monitoring of coagulation parameters.
• Central nervous system-affecting drugs (benzodiazepines, alcohol) may enhance sedative effects and impair judgment.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or aspirin may increase bleeding risk.
• Can elevate blood levels of some liver-metabolized medications (anticonvulsants, antipsychotics), potentially increasing side effects.
• Liver enzyme-altering medications may impact Fluoxetine metabolism, requiring caution.

Following are the food interactions for Fluoxetine 20mg/5ml Solution:

• Avoid consuming alcohol while taking Fluoxetine, as it can increase the risk of side effects and may cause drowsiness and dizziness.
• Grapefruit and grapefruit juice should be consumed with caution as they can increase the blood levels of Fluoxetine, potentially leading to an increased risk of side effects.
• Consuming high-fat meals with Fluoxetine may delay the absorption of the medication, but it does not significantly affect its overall effectiveness.
• Avoid tyramine-rich foods like aged cheeses, cured meats, and certain types of beer, as they can interact with Fluoxetine and increase blood pressure.
• Caffeine intake should be monitored as it can exacerbate anxiety and insomnia, which are potential side effects of Fluoxetine.
• Avoid herbal supplements like St. John's Wort, as it can reduce the effectiveness of Fluoxetine and increase the risk of serotonin syndrome.
• There is no specific dietary restriction, but maintaining a balanced diet is advisable for overall well-being during Fluoxetine therapy.
• Always consult your healthcare provider for personalized advice on food interactions based on your medical history.

Fluoxetine 20mg/5ml Solution should be stored in a secure and child-resistant container, preferably in a cool and dry place at room temperature, ensuring it is protected from direct sunlight and moisture. It is crucial to keep the medication in its original packaging, tightly sealed, to maintain its integrity and prevent contamination. When disposing of any remaining solution, avoid pouring it down the drain or flushing it down the toilet. Instead, contact your local pharmacist or healthcare provider for guidance on safe disposal methods to minimize environmental impact. Always prioritize keeping medications away from children to prevent accidental consumption.

Following are the quick tips for Fluoxetine 20mg/5ml Solution:

• Consult a healthcare professional for personalized advice and dosage instructions.
• Measure the solution accurately using the provided measuring device.
• Administer the solution as directed, typically once daily.
• Take it at the same time each day to maintain a consistent routine.
• If you forget a dose, skip it and continue with the next scheduled dose, avoiding double dosing.
• Store the solution at room temperature, away from direct sunlight and moisture.
• Do not freeze the solution.
• Keep the medication out of the reach of children and pets.