Derox 150mg Tab

Roxithromycin 100mg Tablet, a semi-synthetic macrolide antibiotic, exerts its therapeutic effect through multiple mechanisms. Primarily, it inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of susceptible bacteria, thereby preventing the assembly of the 70S ribosome complex. This binding interferes with the translocation of aminoacyl tRNA, ultimately hindering bacterial protein synthesis and leading to bacterial growth inhibition. Roxithromycin is particularly effective against a broad spectrum of bacteria, including gram-positive and some gram-negative bacteria, by disrupting their ability to produce essential proteins required for their survival and replication.

Macrolide antibiotic

Tablet

The following are the uses of Roxithromycin 100mg Tablet:

• Used for treating respiratory tract infections like bronchitis and pneumonia.
• Used for managing skin and soft tissue infections.
• Used to treat acute flare-ups of chronic bronchitis.
• Effective against certain bacterial strains in respiratory infections.
• Used to eliminate bacteria causing skin problems.
• Used for preventing bacterial infections post-surgery.
• Provides relief from symptoms and aids in faster recovery.

In the case of an overdose of Roxithromycin 100mg Tablets, it is important to recognize the potential symptoms and seek medical advice promptly. Overdose symptoms may include gastrointestinal issues such as nausea, vomiting, and abdominal pain. Additionally, individuals may experience temporary hearing loss or tinnitus. It is recommended to contact a healthcare professional or a poison control center for guidance on managing the overdose and determining the appropriate course of action to ensure the individual's well-being.

In the case of a missed dose of Roxithromycin 100mg Tablet, it is important to take the medication as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. However, if you have missed multiple doses, it is best to consult your healthcare provider for guidance on how to proceed. They may advise you to adjust your dosing schedule or provide specific instructions to ensure you receive the full therapeutic benefit of the medication.

To take Roxithromycin 100mg Tablet, swallow the tablet whole with a full glass of water, preferably with or after a meal, once or twice a day as directed by your healthcare professional, ensuring you complete the full prescribed course of medication.

Here are the conditions and situations when Roxithromycin 100mg Tablet should not be taken:

• Avoid if you have a known allergy to Roxithromycin or any macrolide antibiotics.
• Do not use if you have a history of liver problems or if you have severe liver disease.
• Contraindicated in patients with a prolonged QT interval or heart rhythm disorders.
• Not suitable for patients with myasthenia gravis.
• Should not be used in individuals with a rare genetic problem of galactose intolerance.
• Avoid if you have severe kidney problems or are on dialysis.
• Not recommended for children under 12 years of age and the elderly, as dosage adjustments may be required.
• Do not take if you have ever had jaundice or other liver problems after taking Roxithromycin or similar antibiotics.
• Contraindicated in patients with porphyria (a rare genetic enzyme disorder).

The side effects of Roxithromycin 100mg Tablet may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Skin rashes or itching
• Headache
• Dizziness
• Altered sense of taste

Following are the precautions and warnings for Roxithromycin 100mg Tablet:

• Do not take this medication if you have a known allergy to Roxithromycin or any macrolide antibiotics.
• Caution is advised for patients with liver or kidney disease, as Roxithromycin metabolism may be affected, requiring dosage adjustments.
• This medication may cause dizziness or blurred vision; avoid driving or operating machinery until you know how it affects you.
• Inform your doctor if you have a history of cardiovascular disease, as Roxithromycin may rarely cause irregular heart rhythms.
• Avoid prolonged exposure to sunlight or UV rays as Roxithromycin may increase photosensitivity, leading to sunburn.
• Elderly patients may be more susceptible to side effects; regular monitoring is advised.
• Roxithromycin may interact with other medications; inform your doctor about all the medicines you are taking.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as it may have potential risks to the fetus or infant.

Following are the drug interactions for Roxithromycin 100mg Tablet:

• Erythromycin and other macrolide antibiotics may enhance the effects of statins, leading to increased risk of muscle-related side effects.
• Concomitant use with ergotamine or dihydroergotamine can increase the risk of ergot toxicity.
• Roxithromycin may reduce the effectiveness of oral contraceptives, requiring additional contraceptive measures.
• It can elevate plasma concentrations of carbamazepine, requiring monitoring and potential dose adjustment.
• Theophylline levels may increase, necessitating monitoring to prevent theophylline toxicity.
• Co-administration with digoxin can result in increased digoxin levels, requiring close monitoring.
• May interact with warfarin, enhancing its anticoagulant effect, and requiring regular monitoring of INR.

Following are the food interactions for Roxithromycin 100mg Tablet:

• Avoid consuming grapefruit and grapefruit juice as they can interfere with the metabolism of Roxithromycin, potentially increasing its levels in the blood and the risk of side effects.
• Alcohol consumption should be minimized or avoided as it can cause liver damage and increase the risk of adverse effects when combined with Roxithromycin.
• High-fat meals may slightly delay the absorption of Roxithromycin, but this is not considered clinically significant.
• Dairy products like milk and yogurt can reduce the absorption of Roxithromycin; consider spacing out the consumption of these foods and the medication.
• Avoid consuming large amounts of caffeine while on Roxithromycin as it can increase the drug's metabolism, potentially reducing its effectiveness.
• Foods rich in antioxidants, such as berries and dark chocolate, might interact with Roxithromycin and decrease its effectiveness.
• Always ensure you are well-hydrated when taking this medication, as dehydration can affect its absorption and effectiveness.
• Consult your healthcare provider for specific dietary recommendations during your treatment with Roxithromycin.

Roxithromycin 100mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct light and moisture. The original packaging should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to expose the tablets to extreme temperatures, so avoid storing them in hot or humid environments like bathrooms or near heat sources. Always check the expiration date, and if the medication is no longer needed or has expired, proper disposal is essential. Do not dispose of the tablets in wastewater or household garbage; consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep the medication securely stored to prevent access by children, as accidental ingestion can be harmful.

Following are the quick tips for Roxithromycin 100mg Tablet:

• Consult your doctor for the correct dosage and duration tailored to your medical condition.
• Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
• Maintain a consistent schedule for taking the medication, preferably at evenly spaced intervals.
• Complete the full prescribed course, even if you feel better, to ensure infection clearance.
• Store the tablets at room temperature, away from moisture and sunlight, to preserve their effectiveness.
• Inform your doctor about all your current medications to prevent potential drug interactions.
• If you experience mild stomach discomfort, taking the tablet with food can help alleviate it.