Descol (10mg) 10 Tablets

Descol (10mg) 10 Tablets

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  • Manufacturer NABIQASIM PHARMACEUTICALS (PVT.) LTD.
  • Generic Name

    Atorvastatin 10mg

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Control Drug
  • Quick Tips, if any
  • Description

    Atorvastatin, the active ingredient in the 10mg tablet, acts as a potent inhibitor of HMG-CoA reductase, a key enzyme in the liver responsible for cholesterol production. By competitively blocking this enzyme, atorvastatin significantly reduces the production of cholesterol, specifically low-density lipoprotein (LDL) cholesterol. This mechanism of action leads to a decrease in total cholesterol and LDL cholesterol levels in the blood, which are major contributors to cardiovascular disease. Atorvastatin also helps increase high-density lipoprotein (HDL) cholesterol, often referred to as "good" cholesterol, by promoting the expression of LDL receptors in the liver, resulting in enhanced LDL clearance from the bloodstream.

  • Ingredients

    Atorvastatin 10mg

  • Drug Class

    Statin

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Atorvastatin 10mg Tablet:

    • Used for lowering high cholesterol levels in the blood.
    • Used for reducing the risk of heart disease and stroke.
    • Used for managing conditions where the body produces too much cholesterol.
    • Used for preventing the formation of fatty deposits in arteries.
    • Used for improving blood flow and reducing the risk of blood clots.
    • Used for treating certain types of heart and blood vessel disorders.
    • Used for long-term management of high cholesterol, often in combination with lifestyle changes.
  • Dosage

    To be taken as per doctor's prescription

  • In case of Overdose

    In the case of an overdose of Atorvastatin 10mg Tablets, it is important to recognize the potential risks. While generally well-tolerated, excessive amounts may lead to muscle pain, liver damage, or other adverse effects. Promptly contact a healthcare professional or seek medical advice if you suspect an overdose. They can provide guidance and support to address any concerns and ensure appropriate treatment is administered. Quick action can help manage any potential health complications associated with an overdose.

  • Missed Dose

    In the case of a missed dose of Atorvastatin 10mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication or provide alternative instructions. It is generally recommended to take the missed dose within 12 hours of the scheduled time for optimal effectiveness.

  • How To Use

    To take Atorvastatin 10mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, either in the morning or evening, as directed by your healthcare provider, and continue taking it regularly for the prescribed duration.

  • When Not to Use

    Following are the conditions or situations when Atorvastatin 10mg Tablet should not be taken:

    • Should not be used in individuals with a known allergy to Atorvastatin or any HMG-CoA reductase inhibitors.
    • Contraindicated in patients with active liver disease or unexplained elevated liver enzymes.
    • Not suitable for individuals with uncontrolled hypothyroidism.
    • Should not be used in pregnant or breastfeeding women.
    • Avoid using this medication if you have a history of muscle pain or weakness, as it may increase the risk of muscle-related side effects.
    • Contraindicated in individuals with a history of alcohol abuse or heavy drinking.
    • Not recommended for patients with severe kidney disease or those on dialysis.
    • Avoid using this medication if you have a history of hereditary muscle disorders.
  • Side Effects

    The side effects of Atorvastatin 10mg Tablet may include:

    • Muscle pain and weakness
    • Joint pain
    • Nausea and digestive issues
    • Constipation or diarrhea
    • Increased blood sugar levels
    • Skin rash or itching
    • Memory problems or confusion
    • Increased liver enzymes (liver function tests may be affected)
  • Precautions & Warnings

    Following are the precautions and warnings for Atorvastatin 10mg Tablet:

    • Not recommended for individuals with active liver disease or unexplained elevated liver enzymes, as it may cause further liver damage.
    • Regular liver function tests are advised during treatment, and if liver enzymes increase significantly, the medication should be discontinued.
    • Patients with a history of liver problems should use Atorvastatin with caution, and their liver function should be monitored closely.
    • Not suitable for individuals with a known allergy to Atorvastatin or any other statin medication.
    • May cause muscle pain, tenderness, or weakness; if these symptoms occur, medical attention should be sought immediately.
    • Caution is advised when using Atorvastatin with other medications that may increase the risk of muscle problems, such as fibrates or certain antibiotics.
    • Patients with diabetes should monitor their blood sugar levels as Atorvastatin can increase blood sugar levels.
    • Not recommended for pregnant or breastfeeding women as it may cause harm to the developing fetus or infant.
  • Drug Interactions

    Following are the drug interactions for Atorvastatin 10mg Tablet:

    • Gemfibrozil can increase the risk of muscle-related side effects when taken with Atorvastatin, and their combination should be avoided.
    • The effectiveness of Atorvastatin may be reduced when used with certain medications like cyclosporine, increasing the risk of adverse effects.
    • When combined with macrolide antibiotics (e.g., erythromycin), the levels of Atorvastatin in the blood can rise, potentially increasing the risk of muscle-related side effects.
    • Taking Atorvastatin with protease inhibitors (e.g., ritonavir) may lead to higher Atorvastatin levels and an increased risk of myopathy.
    • Antifungal medications like itraconazole can elevate Atorvastatin levels, requiring dose adjustments.
    • Combining Atorvastatin with colchicine may increase the risk of muscle problems and rhabdomyolysis.
    • The blood levels of Atorvastatin may be affected by certain HIV protease inhibitors, necessitating dosage adjustments.
  • Food Interactions

    Following are the food interactions for Atorvastatin 10mg Tablet:

    • Avoid excessive alcohol consumption while taking this medication as it can increase the risk of liver-related side effects.
    • Grapefruit and grapefruit juice should be avoided as they can increase the levels of Atorvastatin in the blood, potentially leading to increased side effects.
    • Foods high in saturated fat and cholesterol should be limited as they can counteract the benefits of Atorvastatin in lowering cholesterol.
    • Avoid high-fat meals as they may increase the absorption of Atorvastatin, leading to higher blood levels of the medication.
    • Avoid eating large amounts of licorice as it may affect the metabolism of Atorvastatin, potentially reducing its effectiveness.
    • Consuming large amounts of cranberry juice may increase the effects of Atorvastatin, so monitor for increased side effects.
    • Avoid or limit the consumption of Seville oranges and products containing them, as they can affect the metabolism of Atorvastatin.
    • Consider limiting the intake of pomegranate juice as it may interact with Atorvastatin, potentially affecting its metabolism.
  • Storage/Disposal

    Atorvastatin 10mg Tablets should be stored in a cool, dry location, preferably at room temperature (68°F to 77°F), in their original container with the lid tightly secured. Protect the tablets from light and moisture to maintain their integrity. It is crucial to keep this medication out of the reach of children and pets to prevent accidental ingestion. Do not store the tablets in the bathroom medicine cabinet or near the kitchen sink, as exposure to heat and moisture can degrade their quality. Dispose of any unused or expired tablets responsibly; do not flush them down the toilet or pour them into drainage systems. Consult your pharmacist or local waste management authority for guidance on proper disposal methods.

  • Control Drug

    No

  • Quick Tips, if any

    Following are the quick tips for Atorvastatin 10mg Tablet:

    • Take the tablet at the same time each day to maintain a consistent level in your blood.
    • Swallow the tablet whole with a full glass of water, preferably at night.
    • Atorvastatin is best taken when your stomach is empty.
    • Avoid consuming grapefruit or grapefruit juice while on this medication.
    • Do not crush, chew, or break the tablet, as it may affect its effectiveness.
    • Inform your doctor about all medications you are taking to prevent potential drug interactions.
    • Regularly monitor your blood sugar and cholesterol levels as advised by your healthcare provider.
    • Store the tablets in a cool, dry place, away from direct sunlight and moisture.

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