Deslo (0.5mg/ml) 120ml Syrup

Desloratadine 5mg syrup/suspension works primarily by selectively blocking peripheral histamine H1 receptors. It is a tricyclic histamine antagonist, structurally similar to loratadine, but with increased potency and selectivity. By blocking the H1 receptors, desloratadine inhibits the action of histamine, a key mediator of allergic reactions. This mechanism helps to reduce the symptoms associated with allergies, such as sneezing, itching, and runny nose, by preventing the activation of cells that release additional allergic mediators. Desloratadine's high selectivity for the H1 receptors means it has minimal impact on other receptors, contributing to its reduced sedative effects compared to some other antihistamines.

Desloratadine 5mg

Antihistamine

Suspension

The following are the uses of Desloratadine 5mg Syrup/Suspension:

• Used for relieving symptoms of seasonal allergies such as sneezing, runny nose, and itchy eyes.
• Used for treating chronic hives and skin itching.
• Used to reduce inflammation and irritation caused by allergies.
• Used for preventing allergic reactions and managing long-term allergies.
• Used for improving quality of life by reducing allergy-related discomfort.
• Used in both adults and children for allergy symptom relief.
• Used as an alternative for individuals who prefer a liquid medication.

In the case of an overdose of Desloratadine 5mg Syrup/Suspension, it is important to remain calm and take immediate action. Contact a healthcare professional or a poison control center for guidance. They will provide specific instructions based on the amount ingested and the individual's health status. Common symptoms of an overdose may include drowsiness, dizziness, and dry mouth, but seek professional advice for an accurate assessment and appropriate treatment.

In the case of a missed dose of Desloratadine 5mg Syrup/Suspension, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently forget doses, consider setting reminders or asking someone to remind you to take your medication at the prescribed times.

To administer Desloratadine 5mg Syrup/Suspension, shake the bottle vigorously, measure the prescribed dose with an accurate measuring device like a marked measuring spoon or oral syringe, and take it once daily as directed by your healthcare provider, with or without food, following the dosage instructions provided.

Here are the conditions or situations when Desloratadine 5mg Syrup/Suspension should not be used:

• Avoid in individuals with a known allergy or hypersensitivity to Desloratadine or any other antihistamines.
• Not suitable for patients with a rare hereditary condition called galactose intolerance.
• Should not be used in patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption, or sucrase-isomaltase insufficiency.
• Contraindicated in patients with severe kidney problems.
• Not recommended for infants under 1 year of age due to the syrup/suspension formulation.
• Avoid in patients with a history of severe or uncontrolled heart disease.
• Should not be used if the patient is taking other medications that may interact negatively with Desloratadine.

The side effects of Desloratadine 5mg Syrup/Suspension may include:

• Drowsiness or fatigue
• Headache
• Dry mouth
• Nausea or stomach discomfort
• Diarrhea
• Dizziness
• Sore throat
• Skin rash or itching

Here are the precautions and warnings for Desloratadine 5mg Syrup/Suspension:

• Desloratadine should not be used in individuals with a known hypersensitivity or allergy to Desloratadine or any other antihistamines of similar class.
• This medication may cause drowsiness or dizziness in some individuals. Avoid driving, operating heavy machinery, or performing tasks requiring mental alertness until you know how the medication affects you.
• Caution is advised in patients with liver or kidney disease, as Desloratadine is primarily metabolized by the liver and excreted by the kidneys. Dosage adjustments may be necessary.
• Elderly patients may be more susceptible to the side effects of Desloratadine, particularly drowsiness and confusion. Close monitoring is recommended.
• Desloratadine should be used with caution in patients with a history of seizures or epilepsy, as it may lower the seizure threshold.
• Avoid alcohol consumption while taking Desloratadine, as it can increase the risk of side effects, including drowsiness and impaired coordination.
• Pregnant and breastfeeding women should consult their healthcare provider before using Desloratadine, as the effects on the fetus and infant are not fully established.
• Store Desloratadine 5mg Syrup/Suspension at room temperature, away from direct sunlight and moisture, and keep out of reach of children.

Following are the drug interactions for Desloratadine 5mg Syrup/Suspension:

• Concomitant use with alcohol, sedatives, or other central nervous system depressants may cause increased drowsiness and impaired alertness.
• Desloratadine can interact with erythromycin, ketoconazole, and other CYP3A4 inhibitors, potentially leading to increased concentrations and side effects.
• It may decrease the effectiveness of certain antifungal medications like ketoconazole and itraconazole.
• Avoid use with strong CYP3A4 inducers like rifampin, as it may reduce Desloratadine's effectiveness.
• Antihistamines can reduce the effectiveness of certain vaccines, such as influenza or pneumococcal vaccines, if given concurrently.
• The medication may interact with antiepileptic drugs, affecting seizure control.
• Caution is advised when using Desloratadine with other medications that prolong the QT interval, as it may increase the risk of cardiac arrhythmias.

Following are the food interactions for Desloratadine 5mg Syrup/Suspension:

• Desloratadine can be taken with or without food, but it is recommended to take it with food if you experience an upset stomach.
• Avoid consuming large amounts of grapefruit or grapefruit juice as it may affect the metabolism of the medication.
• Alcohol consumption is generally not advised with antihistamines like Desloratadine as it may increase drowsiness and impair your ability to think and react.
• Caffeine-containing beverages such as coffee, tea, or energy drinks should be limited as they may counteract the sedating effects of Desloratadine, making it less effective for allergy symptoms.
• Avoid eating large, heavy meals right after taking the medication, as it may slow down the absorption of Desloratadine.
• Do not mix the syrup with dairy products like milk or yogurt as it may interfere with the absorption of the medication.
• Certain foods rich in vitamin C, like oranges and strawberries, may enhance the absorption of Desloratadine, but they are generally safe to consume.
• There are no specific food restrictions, but maintaining a balanced diet is always advisable for overall health.

Desloratadine 5mg Syrup/Suspension should be stored in a secure location, preferably a locked medicine cabinet, at room temperature (68°F to 77°F) with brief excursions permitted between 59°F and 86°F. Protect the medication from light and moisture by keeping it in its original container with the cap tightly closed. It is crucial to store this medication away from children and pets to prevent accidental ingestion. Do not use the medication if it has changed color, becomes cloudy, or if you notice particles in the liquid. Dispose of any unused or expired syrup responsibly; do not pour it down the drain or flush it down the toilet. Contact your pharmacist or local waste management authority for guidance on safe disposal practices to minimize environmental impact.

Following are the quick tips for Desloratadine 5mg Syrup/Suspension:

• Always take the syrup as directed by your doctor or pharmacist.
• Administer the correct dose using the measuring device provided.
• Mix the syrup well before each use to ensure uniformity.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Do not freeze the syrup as it may affect its potency.
• Check the expiration date and discard if it has passed.
• Contact your healthcare provider if symptoms persist or worsen.
• Inform your doctor about any other medications you are taking.