DeVit (2400 I.E./ml ) 10ml Oral Drops

Cholecalciferol, also known as vitamin D3, has a primary mechanism of action centered on its role in calcium and phosphate metabolism. When administered, cholecalciferol is converted in the liver and kidneys to form the active hormone calcitriol (1,25-dihydroxyvitamin D3). Calcitriol binds to specific vitamin D receptors (VDRs) located in various target tissues, particularly in the intestines, bones, and kidneys. This binding activates the VDR, which then regulates gene expression, leading to increased intestinal absorption of calcium and phosphate. By promoting the absorption of these minerals, cholecalciferol helps maintain adequate serum calcium and phosphate levels, which are essential for proper bone mineralization and overall bone health. Additionally, cholecalciferol's action on VDRs influences the regulation of bone remodeling processes, promoting bone growth and strength.

Cholecalciferol 2,400iu

Vitamin D analog

Drop

The following are the uses of Cholecalciferol 2,400iu Drop:

• Used for treating and preventing Vitamin D deficiency
• Used to support bone and teeth health
• Used in the treatment of rickets, a condition caused by Vitamin D deficiency
• Used to regulate calcium and phosphate levels in the body
• Used to improve muscle strength and immune function
• Used for overall health and well-being, especially in individuals with limited sun exposure
• Used to support the absorption of calcium and phosphorus from the digestive tract
• Used to maintain a healthy immune response

In the case of an overdose of Cholecalciferol 2,400iu Drops, it is important to recognize the potential risks. Excessive intake can lead to vitamin D toxicity, causing symptoms such as nausea, vomiting, and extreme thirst. If you suspect an overdose, seek medical advice promptly. Treatment may involve monitoring vitamin D levels and providing supportive care to manage symptoms until the excess vitamin D is eliminated from the body. Timely intervention is crucial to prevent potential complications.

In the case of a missed dose of Cholecalciferol 2,400iu Drops, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare professional for guidance on how to safely resume your vitamin D supplementation.

To administer Cholecalciferol 2,400 IU drops, place the prescribed number of drops directly under the tongue using the dropper provided, holding it there for a brief period to allow for absorption before swallowing.

Here are the conditions and situations when Cholecalciferol 2,400iu Drop should not be taken:

• Do not use if you have a known allergy or hypersensitivity to vitamin D or any of the drop's components.
• Avoid if you have hypervitaminosis D (excess vitamin D in the body) or conditions causing elevated calcium levels, such as hypercalcemia or hypercalciuria.
• Should not be used in individuals with kidney stones or conditions that cause calcium to build up in the kidneys.
• Not recommended for individuals with hyperparathyroidism (overactive parathyroid gland).
• Contraindicated in patients with a history of kidney disease or impaired kidney function.
• Do not use if you have a condition called sarcoidosis, as it may affect calcium metabolism.
• Avoid if you have Williams syndrome, a genetic disorder affecting calcium regulation.

The side effects of Cholecalciferol 2,400 IU Drop may include:

• Nausea and vomiting
• Weakness and fatigue
• Dry mouth
• Metallic taste
• Constipation or diarrhea
• Loss of appetite
• Muscle or joint pain

Following are the precautions and warnings for Cholecalciferol 2,400iu Drop:

• Do not exceed the recommended dosage, as excessive vitamin D intake can lead to hypervitaminosis D and potential harm.
• Regularly monitor vitamin D levels in the body, especially during long-term use, to ensure they remain within the desired range.
• Patients with a history of kidney stones or hypercalcemia should exercise caution and consult a healthcare professional before use.
• Those with conditions affecting calcium metabolism, such as hyperparathyroidism, should use this medication under medical supervision.
• Inform your doctor about any other medications or supplements you are taking to avoid potential interactions.
• Cholecalciferol drops should be administered with caution in infants and young children, ensuring accurate dosing.
• Patients with a history of malabsorption syndromes may require higher doses or alternative forms of vitamin D supplementation.
• Discontinue use and seek medical attention if any adverse reactions or allergic responses occur.

Following are the drug interactions for Cholecalciferol 2,400 IU Drop:

• It can decrease the effectiveness of medications like cholestyramine, colestipol, orlistat, and mineral oil, which may require adjustments in vitamin D dosage.
• Anticonvulsants such as phenobarbital, phenytoin, and carbamazepine can reduce vitamin D levels, requiring higher doses for optimal effect.
• Corticosteroids like prednisone may increase vitamin D metabolism, necessitating higher doses to maintain adequate levels.
• Aluminum-containing antacids may decrease vitamin D absorption, potentially requiring higher doses.
• Thiazide diuretics can increase calcium levels, and when combined with vitamin D, may lead to hypercalcemia.
• Vitamin D can enhance the absorption of aluminum in the body, which is of concern in patients with impaired kidney function.
• Certain medications, such as ketoconazole, cimetidine, and certain HIV protease inhibitors, can affect liver enzymes and potentially alter vitamin D metabolism.

Following are the food interactions for Cholecalciferol 2,400 IU Drop:

• Consuming foods rich in Vitamin D, such as fatty fish (salmon, tuna), egg yolks, and fortified dairy products, alongside the supplement may lead to Vitamin D toxicity if not monitored.
• Vitamin D is fat-soluble, so taking it with a small meal containing healthy fats can enhance its absorption.
• Avoid excessive consumption of calcium-rich foods like dairy products and calcium-fortified juices, as Vitamin D increases calcium absorption, potentially leading to hypercalcemia.
• Limit caffeine intake from coffee, tea, or energy drinks, as caffeine may interfere with Vitamin D metabolism and reduce its effectiveness.
• Avoid excessive alcohol consumption, as it can hinder Vitamin D absorption and impair its activation in the body.
• Maintain a balanced diet with a variety of nutrients, as Vitamin D works synergistically with other vitamins and minerals like Vitamin K, magnesium, and zinc.
• Consider consulting a dietitian or healthcare provider for personalized advice, especially if you have specific dietary restrictions or health conditions.

Cholecalciferol 2,400iu Drops should be stored in a cool and dry place, preferably at room temperature (20-25°C), away from direct sunlight, heat, and moisture. Ensure the bottle is tightly sealed after each use to maintain its potency and prevent contamination. Always check the expiration date on the packaging, and never use the medication beyond this date. For proper disposal, do not flush or pour the drops down the drain; instead, consult a pharmacist or local waste management guidelines for safe disposal practices. Keep the medication out of sight and reach of children and pets to prevent accidental ingestion, as it can be harmful if consumed without medical supervision. It is essential to handle and store this medication with care to ensure its effectiveness and safety.

Following are the quick tips for Cholecalciferol 2,400iu Drop:

• Take the drops as directed by your doctor or pharmacist, typically once daily or as instructed.
• Administer the drops directly into the mouth or mix with food or beverages as recommended.
• Ensure the dropper is clean before each use to maintain hygiene.
• Store the drops in a cool, dry place, away from direct sunlight and moisture.
• Avoid taking more than the prescribed dose to prevent potential side effects.
• Inform your healthcare provider if you have any underlying medical conditions or are taking other medications.
• Regularly monitor your vitamin D levels as advised by your healthcare professional.