Dewnac SR 100mg

Paracetamol, Serratiopeptidase, and Aceclofenac in combination form a potent analgesic and anti-inflammatory medication. Paracetamol primarily acts as a central analgesic, inhibiting the synthesis of prostaglandins in the brain, thereby reducing pain and fever. Serratiopeptidase, a proteolytic enzyme, promotes the breakdown of inflammatory mediators, reducing inflammation and facilitating tissue repair. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), exerts its action by inhibiting cyclooxygenase (COX) enzymes, particularly COX-2, which suppresses the production of prostaglandins responsible for pain and inflammation at the site of injury. This combination synergistically addresses pain and inflammation through multiple pathways, providing effective relief.

Analgesic, Anti-inflammatory, Enzyme.

Tablet

The following are the uses of Paracetamol, Serratiopeptidase, Aceclofenac Tablet:

• Used for relieving pain and reducing fever
• Used to treat acute pain and inflammation, especially in conditions like osteoarthritis and rheumatoid arthritis
• Used for reducing swelling and promoting healing in cases of sports injuries, sprains, and post-operative pain
• Used for managing dental pain and discomfort
• Used to alleviate headache and migraine symptoms
• Used for reducing menstrual pain and discomfort
• Used for providing temporary relief from backache and muscle pain

In the case of an overdose of Paracetamol, Serratiopeptidase, and Aceclofenac Tablet, individuals may experience symptoms such as nausea, vomiting, abdominal pain, and potential liver damage. It is important to seek medical advice promptly, as treatment options can vary depending on the severity of the overdose. Quick action can help minimize the potential harm caused by excessive consumption of these medications.

In the case of a missed dose of Paracetamol, Serratiopeptidase, and Aceclofenac Tablet, it is important to take the dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. It is recommended to take the medication as prescribed by your healthcare professional to ensure maximum effectiveness and avoid any potential side effects.

To take the Paracetamol, Serratiopeptidase, and Aceclofenac Tablet, swallow the tablet with a glass of water, preferably with or after a meal, following the dosage instructions provided by your healthcare professional.

Following are the conditions or situations when Paracetamol, Serratiopeptidase, Aceclofenac Tablet should not be used:

• Avoid if allergic to any of the components, especially Paracetamol, Serratiopeptidase, or Aceclofenac.
• Not suitable for individuals with a history of gastrointestinal bleeding or perforation.
• Contraindicated in patients with severe heart failure or cardiovascular disease.
• Should not be used in patients with severe kidney or liver impairment.
• Not recommended for individuals who have recently undergone coronary artery bypass graft (CABG) surgery.
• Avoid if you have a history of asthma or allergic reactions triggered by Aspirin or other NSAIDs.
• Do not use if you have a bleeding disorder or if you are taking blood-thinning medications.
• Not suitable for individuals with a history of peptic ulcers or gastrointestinal disorders.

The side effects of Paracetamol, Serratiopeptidase, and Aceclofenac Tablet may include:

• Stomach pain or discomfort
• Nausea and vomiting
• Diarrhea
• Dizziness or vertigo
• Skin rashes or itching
• Increased liver enzymes
• Headache
• Drowsiness or fatigue

Following are the precautions and warnings for Paracetamol, Serratiopeptidase, Aceclofenac Tablet:

• This medication should not be used by individuals with known allergies to any of its components, including Paracetamol, Serratiopeptidase, and Aceclofenac.
• Patients with a history of gastrointestinal bleeding, asthma, or liver/kidney impairment should exercise caution and consult a healthcare professional before use.
• Avoid alcohol consumption while taking this medication as it may increase the risk of gastrointestinal bleeding.
• Aceclofenac may increase blood pressure, so blood pressure monitoring is recommended during long-term use.
• Serratiopeptidase may cause skin rash or itching; discontinue use if these symptoms occur.
• Do not take this medication if you are pregnant, planning to become pregnant, or breastfeeding without consulting your doctor.
• If you are taking any other medications, especially anticoagulants or corticosteroids, inform your doctor to prevent potential drug interactions.

Following are the drug interactions for Paracetamol, Serratiopeptidase, and Aceclofenac Tablet:

• May increase risk of bleeding when taken with anticoagulants like warfarin, requiring close monitoring of INR (International Normalized Ratio).
• Can interact with other non-steroidal anti-inflammatory drugs (NSAIDs) and increase the risk of gastrointestinal bleeding and kidney-related issues.
• May reduce the effectiveness of antihypertensive medications, such as beta-blockers and ACE inhibitors.
• Paracetamol can affect the metabolism of certain drugs, including warfarin, leading to potential changes in their effects.
• Serratiopeptidase may enhance the absorption of certain antibiotics, such as amoxicillin and cefuroxime.
• Aceclofenac can increase the plasma concentration of lithium, potentially requiring a dosage adjustment.
• Use with corticosteroids may increase the risk of gastrointestinal ulceration and bleeding.
• Caution is advised when combining with other drugs that affect kidney function, as it may exacerbate renal toxicity.

Following are the food interactions for Paracetamol, Serratiopeptidase, Aceclofenac Tablet:

• Alcohol consumption should be avoided as it can increase the risk of liver damage, especially with Paracetamol, and may enhance the risk of gastrointestinal bleeding with Aceclofenac.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit liver enzymes, potentially affecting the metabolism of Aceclofenac and increasing its concentration in the body.
• High-fat meals may delay the absorption of Aceclofenac, leading to a slight delay in the onset of its effects.
• Spicy foods and hot beverages Aceclofenac may cause gastrointestinal irritation, and spicy foods or hot drinks can exacerbate this, potentially causing stomach discomfort or ulcers.
• Dairy products While not a direct interaction, some individuals may experience lactose intolerance symptoms when taking Aceclofenac with dairy, due to its potential gastrointestinal side effects.
• Salt intake Aceclofenac may cause water retention, and a high-salt diet can exacerbate this, leading to increased blood pressure.
• Vitamin K-rich foods Aceclofenac may affect blood clotting, and consuming excessive vitamin K-rich foods like leafy greens may reduce the medication's effectiveness in this regard.
• Avoid caffeine-rich foods and beverages as they can potentially increase the risk of nervousness and insomnia, especially when combined with Serratiopeptidase.

Store and dispose of Paracetamol, Serratiopeptidase, and Aceclofenac Tablets with care. Keep the tablets in their original packaging at room temperature, away from moisture and direct sunlight. Avoid extreme temperatures and do not store in the bathroom or kitchen. Ensure the container is tightly sealed to maintain its integrity. Check the expiration date regularly, and if the medication is expired or no longer needed, do not flush or pour it down the drain. Contact your pharmacist or healthcare provider for instructions on safe disposal methods. Keep the medication away from children to prevent accidental consumption.

Following are the quick tips for Paracetamol, Serratiopeptidase, Aceclofenac Tablet:

• Consult your doctor before use, especially if you have liver or kidney issues.
• Take the tablet with a full glass of water, preferably after meals.
• Avoid alcohol consumption while taking this medication.
• Do not crush or chew the tablet; swallow it whole.
• If you experience stomach discomfort, try taking it with food.
• Ensure you complete the full prescribed course, even if you feel better earlier.
• Store the medication in a cool, dry place, away from direct sunlight.