Dexsul (0.1/10%) 5ml Eye Drops

Dexamethasone, a potent synthetic corticosteroid, exerts its anti-inflammatory and immunosuppressive effects by binding to cytoplasmic glucocorticoid receptors, leading to the regulation of various genes involved in inflammation. It inhibits the release of inflammatory mediators, reduces capillary permeability, and suppresses immune cell activity. Sulphacetamide, on the other hand, is a sulfonamide antibiotic that interferes with the synthesis of folic acid in susceptible bacteria, thereby inhibiting their growth. When applied topically to the eyes, sulphacetamide inhibits the growth of common ocular pathogens, helping to treat or prevent bacterial infections.

Dexamethasone, Sulphacetamide

Corticosteroid, Sulfonamide

drop

The following are the uses of Dexamethasone, Sulphacetamide Drop:

• Used for treating eye infections and inflammation caused by bacteria or other irritants.
• Used for reducing redness, swelling, and pain associated with eye conditions.
• Used for managing allergic conjunctivitis and other allergic eye reactions.
• Used for preventing and treating eye infections after eye surgery or injury.
• Used for alleviating eye discomfort and itching.
• Used for promoting healing and reducing the risk of eye damage.
• Used for providing temporary relief from eye irritation and foreign body sensation.

In the case of an overdose of Dexamethasone, Sulphacetamide Drops, individuals may experience increased side effects such as severe nausea, vomiting, dizziness, and blurred vision. In more serious cases, it can lead to rapid weight gain, fluid retention, and difficulty breathing. It is important to seek medical advice if an overdose is suspected, as prompt treatment can help alleviate these symptoms and prevent potential complications, especially if there are pre-existing medical conditions.

In the case of a missed dose of Dexamethasone, it is recommended to take the missed dose as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. For Sulphacetamide Drops, if you miss a dose, apply the drops as soon as you remember, but if it is almost time for your next application, skip the missed dose and continue with your regular schedule. Do not apply extra drops to make up for the missed dose.

To use Dexamethasone and Sulphacetamide eye drops, gently tilt your head back, pull the lower eyelid down to create a pocket, and hold the dropper tip close to but without touching the eye, then squeeze the prescribed number of drops into the pocket, blinking gently to allow the medication to spread over the eye surface, and maintain proper hygiene by avoiding touching the dropper tip to prevent contamination.

Following are the conditions/situations when Dexamethasone, Sulphacetamide Eye Drops should not be used:

• Should not be used if you have a known allergy or hypersensitivity to dexamethasone, sulphacetamide, sulfonamides, or any of the other ingredients in the eye drops.
• Not suitable for individuals with untreated bacterial, viral, or fungal eye infections.
• Should not be used if you have a history of eye herpes (herpes simplex keratitis).
• Contraindicated in patients with untreated glaucoma or those with a history of glaucoma.
• Not recommended for individuals with tuberculosis of the eye.
• Should not be used in patients with a history of eye surgery or eye trauma until the eye has completely healed.
• Do not use if you have a corneal ulcer or abrasion.
• Avoid using these eye drops if you have a perforation or rupture of the eardrum (for ear drops).

The side effects of Dexamethasone, Sulphacetamide Drop may include:

• Increased eye pressure
• Allergic reactions such as itching, redness, or swelling
• Eye discomfort or irritation
• Blurred vision or changes in vision
• Dry eyes or eye discharge
• Slow wound healing
• Sensitivity to light

Following are the precautions and warnings for Dexamethasone, Sulphacetamide Eye Drops:

• Do not use if you are allergic to any of the ingredients, including dexamethasone or sulfacetamide.
• This medication is for external use only in the eyes. Do not swallow or inject.
• Avoid wearing contact lenses while using the eye drops, as they may contain preservatives that can be absorbed by the lenses.
• Prolonged use of corticosteroid eye drops may lead to increased intraocular pressure, glaucoma, and cataracts. Regular eye pressure checks are recommended.
• If you have a history of eye infections, herpes simplex keratitis, or other eye diseases, use with caution and under medical supervision.
• Children should use this medication only under the supervision of a healthcare professional.
• Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before using these eye drops.

Following are the drug interactions for Dexamethasone, Sulphacetamide Drop:

• Dexamethasone can interact with non-steroidal anti-inflammatory drugs (NSAIDs), increasing the risk of gastrointestinal bleeding.
• Concomitant use with other immunosuppressants may increase the risk of infection and suppress the immune system further.
• Sulphacetamide may reduce the effectiveness of oral anticoagulants, requiring close monitoring of coagulation parameters.
• It can decrease the efficacy of oral contraceptives, and alternative birth control methods should be considered.
• Dexamethasone can interact with antidiabetic medications, making blood sugar control more challenging.
• Caution is advised when using with cardiac glycosides, as it may increase the risk of cardiac arrhythmias.
• The effect of antihypertensive medications may be reduced due to the mineralocorticoid activity of dexamethasone.

Following are the food interactions for Dexamethasone, Sulphacetamide Drop:

• Avoid consuming high-sodium foods while using Dexamethasone, as it can lead to increased sodium retention and elevated blood pressure.
• Limit the intake of foods containing high levels of potassium, as Dexamethasone can cause potassium loss.
• Sulphacetamide may alter the taste perception, so it's best to avoid strong-flavored foods that may interfere with the medication's effectiveness.
• Alcohol should be avoided as it can increase the risk of gastrointestinal bleeding, especially when combined with Dexamethasone.
• Consume a balanced diet to maintain overall health, as Dexamethasone can affect the body's nutrient absorption.
• Avoid grapefruit and grapefruit juice, as they may interfere with the medication's metabolism, leading to increased side effects.
• No specific food restrictions are associated with Sulphacetamide, but maintaining a healthy diet is advised.
• Stay hydrated by drinking plenty of water, especially when using eye drops, to ensure eye comfort and medication effectiveness.

Dexamethasone, Sulphacetamide eye drops require careful storage and disposal to maintain their effectiveness and ensure safety. Store the drops in a cool, dry place, preferably at room temperature, away from direct sunlight and heat sources like ovens or radiators. Keep the bottle tightly sealed in its original packaging to maintain sterility and prevent contamination. Always check the expiration date, and never use the drops after this date. Dispose of any unused or expired medication responsibly; do not flush or pour down the drain. Contact your pharmacist or healthcare provider for guidance on proper disposal methods in your area. Keep the drops out of children's reach to prevent accidental exposure or ingestion. Responsible storage and disposal practices are crucial for both safety and environmental reasons.

Following are the quick tips for this:

• Take it as prescribed, usually once daily in the morning.
• Ensure you understand the dosage instructions from your doctor.
• Do not stop the medication suddenly; taper as directed.
• Monitor blood pressure and blood sugar levels regularly.
• Avoid alcohol to prevent stomach irritation.
• Inform your doctor about all medications you take.
• Store in a cool, dry place, away from light.
• Wash your hands before using the eye drops.
• Tilt your head back, and gently pull down the lower eyelid.
• Place the prescribed number of drops into the eye.
• Close your eye gently and tilt your head forward to prevent the drops from draining out.
• Avoid touching the dropper tip to your eye or any surface to prevent contamination.
• Do not wear contact lenses while using the drops unless advised by your doctor.
• Store the drops at room temperature, away from light and moisture.