Diaid 120ml Syrup

Holarrhena Antidysenterica, commonly known as kurchi, contains active compounds such as conessine and kurchine alkaloids, which are responsible for its medicinal properties. The primary mechanism of action involves these alkaloids, which exert antimicrobial and astringent effects. Conessine, in particular, has demonstrated antibacterial activity against various pathogens, including those associated with dysentery and gastrointestinal infections. It disrupts bacterial cell membranes, inhibiting their growth and survival. Additionally, the astringent properties of Holarrhena Antidysenterica help reduce inflammation and control excessive mucous secretion in the gastrointestinal tract, thereby alleviating symptoms associated with diarrhea and dysentery.

Holarrhena Antidysenterica

Antidysenteric agent

Suspension

The following are the uses of Holarrhena Antidysenterica Syrup/Suspension:

• Used for treating dysentery and diarrhea due to its astringent and antidiarrheal properties.
• Used for reducing intestinal inflammation and providing relief from abdominal pain and cramps.
• Used for its antimicrobial effects, helping to combat bacterial and parasitic infections in the gastrointestinal tract.
• Used for improving digestion and reducing excessive intestinal motility.
• Used for managing symptoms of irritable bowel syndrome (IBS) and restoring normal bowel function.
• Used for strengthening the digestive system and promoting overall gut health.
• Used for its bitter tonic action, stimulating appetite and supporting digestive processes.

In the case of an overdose of Holarrhena Antidysenterica Syrup/Suspension, symptoms may include nausea, vomiting, abdominal pain, and severe diarrhea. The severity of these symptoms can vary depending on the amount ingested. It is important to seek medical advice immediately and provide the healthcare professional with details of the product and quantity consumed. Quick action can help mitigate potential health risks associated with an overdose.

In the case of a missed dose of Holarrhena Antidysenterica Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. If you miss multiple doses, consult your healthcare professional for guidance on how to resume the medication and maintain its effectiveness. Always keep a consistent dosing routine to ensure the medication works as intended.

To take Holarrhena Antidysenterica Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring cup or oral syringe, and administer it orally, following the dosage instructions provided by your healthcare professional.

Following are the conditions/situations when Holarrhena Antidysenterica Syrup/Suspension should not be used:

• Allergic reactions Should not be used if you have a known allergy or sensitivity to Holarrhena Antidysenterica or any of its components.
• Pregnancy and breastfeeding Contraindicated in pregnant and breastfeeding women, as it may have adverse effects on fetal development and there is limited information on its excretion in breast milk.
• Liver disease Not recommended for individuals with liver disorders or impaired liver function.
• Thrombocytopenia Should be avoided in patients with low platelet counts or bleeding disorders.
• Hypotension Not suitable for individuals with low blood pressure, as it may further lower blood pressure.
• Gastrointestinal obstruction Should not be used in cases of gastrointestinal blockages or severe constipation.
• Children and elderly May require medical supervision and dosage adjustments in children and the elderly.
• Surgery Discontinue use at least 2 weeks before any scheduled surgery due to its potential effects on bleeding.

The side effects of Holarrhena Antidysenterica Syrup/Suspension may include:

• Nausea and vomiting
• Dry mouth
• Constipation
• Diarrhea (in rare cases)
• Dizziness
• Skin rash or itching
• Headache
• Allergic reactions (e.g., swelling, difficulty breathing)

Following are the precautions and warnings for Holarrhena Antidysenterica Syrup/Suspension:

• Not suitable for individuals with a known allergy to Holarrhena Antidysenterica or any of its constituents.
• Patients with liver or kidney issues should use with caution, as it may require dosage adjustments under medical supervision.
• Avoid alcohol consumption while using this syrup, as it may increase the risk of liver damage.
• Do not drive or operate heavy machinery if the syrup causes dizziness or sleepiness.
• Keep out of reach of children. In case of accidental overdose, seek immediate medical attention.
• Holarrhena Antidysenterica Syrup/Suspension should be used with caution in elderly patients, as they may be more sensitive to its effects.
• Always read the patient information leaflet provided with the medication for detailed information.

Following are the drug interactions for Holarrhena Antidysenterica Syrup/Suspension:

• It may interact with other antidiarrheal medications, leading to decreased effectiveness or increased side effects.
• Avoid using with drugs that prolong QT interval, as it may affect heart rhythm.
• Alcohol consumption should be avoided as it may enhance the sedative effects of Holarrhena.
• Drugs that slow blood clotting (e.g., warfarin) may have an additive effect, increasing the risk of bleeding.
• Antacids may reduce the absorption of Holarrhena's active compounds.
• Certain antibiotics (e.g., rifampicin) can induce liver enzymes, potentially reducing the efficacy of Holarrhena.
• May interact with herbal supplements like St. John's Wort, affecting serotonin levels.
• Caution is advised when combining with central nervous system depressants, such as opioids or benzodiazepines.

Following are the food interactions for Holarrhena Antidysenterica Syrup/Suspension:

• Avoid consuming dairy products like milk, cheese, and yogurt, as they may decrease the absorption of the active compounds in the syrup.
• Spicy and oily foods should be limited as they can irritate the digestive system and reduce the effectiveness of the medication.
• Citrus fruits and juices, such as oranges and lemons, may alter the pH of the stomach, potentially affecting drug absorption.
• Avoid alcohol consumption as it can interfere with the medication's efficacy and may cause additional stomach irritation.
• Caffeinated beverages like coffee and tea might increase gut motility, which could counter the desired effects of the syrup.
• Foods rich in fiber, especially insoluble fiber, can bind with the medication and reduce its bioavailability.
• Certain vegetables like broccoli, cabbage, and cauliflower may produce gas and bloating, potentially worsening digestive discomfort.

Holarrhena Antidysenterica Syrup/Suspension should be stored in a cool and dry place, preferably at room temperature, ensuring it is protected from direct sunlight and moisture. Keep the syrup securely closed within its original packaging to maintain its integrity and prevent contamination. Avoid storage in areas like bathrooms or near heat-emitting appliances, as temperature fluctuations can impact the medication's effectiveness. Dispose of any remaining or expired syrup responsibly; refrain from discarding it via toilet flushing or drainage systems. Consult your pharmacist or healthcare professional for appropriate disposal practices. Additionally, ensure the medication is stored out of children's reach to prevent accidental consumption.

Following are the quick tips for Holarrhena Antidysenterica Syrup/Suspension:

• Follow the dosage instructions provided by your healthcare professional for effective treatment.
• Ensure you shake the bottle thoroughly before each use to maintain a consistent mixture.
• Administer the syrup with water; avoid tea, coffee, or dairy to enhance absorption.
• Maintain a consistent schedule for taking the syrup to maximize its benefits.
• If stomach irritation occurs, consider taking the syrup with food for relief.
• Store the syrup safely away from children to prevent unintended consumption.
• Consult your doctor if symptoms persist or worsen during treatment.
• Do not share this medication with others; individual prescriptions are tailored to specific needs.