Diarox (50mg) 10 Capsules

Diacerein 50mg Capsule primarily works by inhibiting interleukin-1 beta (IL-1β) production, a key inflammatory cytokine involved in the pathogenesis of osteoarthritis. It suppresses the activity of enzymes responsible for the synthesis of IL-1β, thereby reducing inflammation and cartilage degradation in the affected joints. By modulating the inflammatory response, Diacerein helps alleviate the symptoms of osteoarthritis and potentially slows down the progression of joint damage. This mechanism of action makes Diacerein a valuable therapeutic option for managing the symptoms and modifying the disease process in osteoarthritis.

Diacerein 50mg

Anti-inflammatory, osteoarthritis medication.

Capsule

The following are the uses of Diacerein 50mg Capsule:

• Used for treating osteoarthritis, relieving joint pain, and improving joint mobility.
• Used to reduce inflammation and slow down joint damage progression.
• Used to manage symptoms of knee osteoarthritis, helping patients maintain physical function.
• Used as a long-term treatment option to improve overall joint health.
• Used to inhibit interleukin-1 beta production, reducing cartilage degradation.
• Used for its chondroprotective properties, promoting cartilage repair.
• Used as an alternative for patients intolerant to other osteoarthritis medications.

To be used as per doctor's instructions

In the case of an overdose of Diacerein 50mg Capsules, it is important to act swiftly. Symptoms may include gastrointestinal discomfort, such as nausea, vomiting, and diarrhea. If you suspect an overdose, seek medical advice immediately. Prompt action can help manage any adverse effects and ensure appropriate treatment. Contact a healthcare professional or go to the nearest emergency room for guidance and assistance.

In the case of a missed dose of Diacerein 50mg Capsule, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one. Never double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for advice on how to safely adjust your dosing schedule and ensure the best treatment outcome. It is generally recommended to set a reminder or use a pill organizer to help you remember to take your medication on time.

To take Diacerein 50mg Capsule, swallow the capsule whole with a full glass of water, preferably with food, once or twice a day as directed by your doctor, and ensure you complete the full course as prescribed.

Following are the conditions when Diacerein 50mg Capsule should not be used:

• Must not be taken by individuals with a known allergy to Diacerein or related substances.
• Contraindicated in patients with severe liver or kidney impairment.
• Not suitable for children under 15 years of age.
• Should not be used during pregnancy and breastfeeding.
• Avoid use if you have a history of stomach or intestinal ulcers.
• Do not take if you have inflammatory bowel disease or intestinal obstruction.
• Contraindicated in patients with a history of allergic reactions to drugs with similar properties (anthraquinones).
• Not recommended for individuals with a rare hereditary problem of fructose intolerance.

The side effects of Diacerein 50mg Capsule may include:

• Nausea and vomiting
• Diarrhea or constipation
• Abdominal pain
• Skin rashes or itching
• Dizziness
• Headache
• Increased liver enzymes (detected in blood tests)
• Allergic reactions (rare)

Following are the precautions and warnings for Diacerein 50mg Capsule:

• Diacerein should not be used in patients with known hypersensitivity or allergy to the drug or its constituents.
• Not recommended for children under 15 years of age due to limited safety data.
• Caution is advised in patients with a history of liver or kidney disease, as it may affect the metabolism and elimination of the drug.
• Diacerein may cause mild gastrointestinal disturbances; patients with a history of gastrointestinal issues should be monitored.
• Patients with a history of bleeding disorders or those taking anticoagulants should be closely monitored for any signs of bleeding.
• This medication may cause skin reactions; immediate medical attention should be sought if any severe skin reactions or rashes occur.
• Not recommended for pregnant or breastfeeding women unless the potential benefits outweigh the risks, as its safety during pregnancy and lactation is not well established.

Following are the drug interactions for Diacerein 50mg Capsule:

• Co-administration with NSAIDs or other analgesics can increase the risk of gastrointestinal bleeding and ulcers.
• May interact with anticoagulants, such as warfarin, potentially enhancing anticoagulant effects and increasing bleeding risk.
• Concomitant use with other drugs that affect renal function, like ACE inhibitors or diuretics, may lead to renal impairment.
• Diacerein may increase the concentration of lithium, requiring close monitoring of lithium levels.
• Caution is advised when combining with drugs that are highly protein-bound, as it may alter their distribution.
• The effectiveness of oral contraceptives may be reduced, requiring additional contraceptive measures.
• Can decrease the absorption of tetracyclines and digoxin, necessitating dosage adjustments.

Following are the food interactions for Diacerein 50mg Capsule:

• Avoid consuming high-fat meals while taking this medication as it may slow down the absorption of Diacerein, potentially reducing its effectiveness.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit enzymes in the liver, potentially affecting the metabolism of Diacerein and increasing the risk of side effects.
• Alcohol may increase the risk of gastrointestinal side effects when taken with Diacerein. It is advisable to limit or avoid alcohol consumption during treatment.
• Dairy products, such as milk, yogurt, and cheese, can bind with Diacerein, reducing its absorption. Consider separating these foods from the time you take the medication.
• Avoid excessive consumption of spicy foods as they may exacerbate gastrointestinal side effects associated with Diacerein.
• Green leafy vegetables rich in vitamin K, like spinach and kale, may interact with Diacerein's blood-clotting effects. Consume these in moderation.
• Foods high in fiber can be beneficial as they may help reduce the gastrointestinal side effects of Diacerein. Include whole grains, fruits, and vegetables in your diet.
• Ensure you stay well-hydrated by drinking plenty of water throughout the day, especially when taking Diacerein, to minimize potential side effects.

Diacerein 50mg Capsules should be stored in a cool, dry, and dark place, preferably in their original packaging or a tightly sealed container. Maintain a consistent room temperature, avoiding exposure to direct sunlight, heat, or moisture to prevent degradation. It's crucial to keep the capsules away from children and pets to ensure safety. Do not use the capsules past their expiration date, and dispose of any unused or expired medication responsibly. To safely discard the capsules, consult your pharmacist or local waste management guidelines for specific instructions on pharmaceutical waste disposal, ensuring environmental protection.

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Following are the quick tips for Diacerein 50mg Capsule:

• Take the capsule with a full glass of water, preferably with food.
• Consume plenty of fluids throughout the day to reduce the risk of kidney stones.
• Avoid taking antacids or iron supplements within 2 hours of taking this medication.
• Do not crush or chew the capsule; swallow it whole for proper absorption.
• If you experience stomach pain or discomfort, inform your doctor.
• Regularly monitor your kidney function and liver enzymes while on this medication.
• Inform your doctor about all medications and supplements you are taking.