Dicloran SR (100mg) 30 Tablets

Diclofenac sodium is a topical agent used for relieving pain and reducing inflammation associated with certain forms of pain, including joint pain caused by arthritis. It is a salt form of diclofenac, locally used for its anti-inflammatory properties, ultimately reducing inflammation and pain. Diclofenac sodium achieves this by inhibiting the enzyme cyclooxygenase, which is involved in the production of prostaglandins, namely molecules that promote inflammation. For this reason, diclofenac sodium is considered a non-steroidal anti-inflammatory drug (NSAID). Typically, diclofenac sodium is absorbed through the skin and acts locally, minimizing the risk of systemic side effects associated with oral diclofenac. However, it is still possible to experience application site reactions, including itching, rash, or burning with topical use. Therefore, diclofenac sodium offers anti-inflammatory and pain-relieving properties, making it a suitable option for those experiencing arthritis-related pain.

Nonsteroidal Anti-inflammatory Drug (NSAID)

Unveiling its multifaceted uses and transformative applications as follows:

• Diclofenac Sodium 100mg is a medication used for treating pain and inflammation associated with joint complaints such as arthritis, bursitis, and tendinitis.
• This medication also serves to reduce nausea and vomiting that may occur during pregnancy.
• Following a doctor's instructions is important to ensure the effectiveness and safety of this medication.
• It is important to inform your doctor about other medications you may be taking to prevent any interactions with diclofenac sodium, which may interact with over-the-counter painkillers, corticosteroids, and other anti-inflammatory drugs.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For pain relief from moderate to severe osteoarthritis of the knee- 100 mg to 150 mg, taken as a single dose or divided into 2 doses (1 tablet of 100 mg 3 times per day).
• For pain relief from rheumatoid arthritis- 100 mg to 150 mg taken once a day or divided into 2 doses (1 tablet of 100 mg 3 times per day).
• For analgesia after dental surgery- 1.8 mg/kg (maximum 150 mg) taken once either before or after surgery.
• For analgesia after general surgery- 2 mg/kg (maximum 200 mg) taken once either before or after surgery.
• For non-specific muscle pain and spasms- 50 mg to 100 mg taken once or twice a day.
• For migraine pain- Initially, 50 mg to 100 mg taken once, and then 25 mg to 50 mg every four hours as needed.
• Maximum dose in a day for oral formulations should not exceed 200 mg

Overdosing on diclofenac sodium is a serious matter and can lead to life-threatening situations if not appropriately treated. If you recognize any signs of an overdose, it is crucial to seek immediate medical attention from a qualified healthcare professional.in the case of an overdose, patients may also require continuous monitoring and additional supportive care to deal with any complications efficiently.It is unsafe and potentially life-threatening to attempt to treat an overdose without medical training. It is strongly advised to seek proper and immediate medical attention to increase the chances of a full recovery.

It is crucial to maintain your medication schedule and ensure you consume your medications as prescribed. If you have missed a dose of Diclofenec Sodium 100mg, here is what you should do. If it is close to the time for your subsequent scheduled dose, take the missed dose immediately. If it is too soon for the next dose, skip the missed dose and continue with your regular dosing schedule. Avoid doubling up on doses to make up for the missed oneIf you are uncertain about the subsequent steps, it is advisable to consult your doctor or pharmacist for guidance. They may provide you with safe and effective ways to catch up with your medication schedule based on your personal circumstances. Taking extra doses or stopping your medication without professional advice can lead to severe health complications.

Before starting the medication, you must read the provided medication guide by the pharmacist. If you have any questions, be sure to contact your doctor or pharmacist. This medication should be taken by mouth, usually three times a day with a full glass of water after meals to prevent stomach upset. Take this medication as directed by your doctor to ensure you're following properly. To reduce the risk of exposure to ulceration or bleeding, take it with food, milk, or an antacid. If you are taking this medication on an empty stomach, it is crucial to take it with a glass of water to avoid any throat irritation. Do not chew, crush, or break the tablets. It may take up to two weeks to feel the full benefit of this medication. Informing your doctor immediately if you experience any signs or symptoms of bleeding in the stomach or intestines is essential. Long-term use can lead to heartburn or stomach ulcers, so monitoring for symptoms of bleeding and peptic ulcers is essential if you have had them before or are taking aspirin or other arthritis medications. This medication may cause dizziness and confusion, which may be worsened if you consume alcohol or are taking certain medications. Do not drive or perform any hazardous tasks until you've determined how this medication affects you. This medication should not be used during pregnancy. Consult a doctor for alternative treatments. This medication passes into breast milk and may cause harm to a nursing infant. It is important to note that this medication may not work for everyone, and side effects may differ from person to person. Contact your doctor if you have any further questions or concerns regarding this medication.

Discerning instances where this medication may not be appropriate:

• If you are allergic to diclofenac (or other NSAIDs), or any of the other ingredients in the medication.
• If you have experienced asthma, hives, or other allergic-type reactions after taking NSAIDs.
• If you have a history of stomach ulcers or other gastrointestinal issues. Diclofenac can cause irritation to the stomach lining and can worsen existing issues.
• If you have kidney disease or impaired kidney function. Diclofenac can exacerbate kidney problems and increase the risk of adverse reactions.
• If you have any cardiovascular conditions such as heart disease, high blood pressure, heart failure, or you have had a stroke.
• If you have any bleeding disorders or are taking blood thinners. Diclofenac can increase the risk of bleeding.
• If you are pregnant or planning to become pregnant. Diclofenac is categorized as a FDA category C drug in pregnancy, which means that it should only be used if the physician deems the benefits outweigh the potential risks.
• If you are breastfeeding, as diclofenac can pass into breast milk and may cause side effects in a nursing baby.

Unraveling the side effects lurking behind this medications are as follows:

• Gastrointestinal complaints

• Kidney injury
• Risk of heart attacks and strokes
• Eye and vision problems, including light sensitivity
• Bone disorders, such as osteomalacia or osteoporosis
• Severe skin reactions

• Effects on the blood

• Respiratory issues

• Persistent headaches, dizziness, ringing in the ears
• Nausea and vomiting persist despite taking medications for stomach irritation
• Fatigue, lethargy, a general feeling of illness
• Acute liver failure

Here are the additional precautions and warnings for Diclofenac Sodium:

• As with other NSAIDs, allergic reactions, including anaphylactic or anaphylactoid reactions, can occur with Diclofenac Sodium, even without prior exposure to the drug. Such hypersensitivity reactions may progress to Kounis syndrome, a serious allergic reaction that can lead to myocardial infarction. Symptoms may include chest pain associated with an allergic reaction to Diclofenac Sodium.
• To minimize undesirable effects, use the lowest effective dose for the shortest duration necessary to control symptoms (see section 4.2 and GI and cardiovascular risks).
• Avoid concomitant use of Diclofenac Sodium with other systemic NSAIDs, including cyclooxygenase-2 selective inhibitors, due to the lack of evidence for synergistic benefits and the potential for additive undesirable effects.
• Caution is advised for the elderly; it is recommended to use the lowest effective dose in frail elderly patients or those with low body weight.
• Like other NSAIDs, Diclofenac Sodium may mask signs and symptoms of infection due to its pharmacodynamic properties.
• Patients with rare hereditary problems such as galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption should not use this medication.
• This medication contains less than 1 mmol sodium (23 mg) per tablet, making it essentially sodium-free.
• Diclofenac Sodium may impair female fertility and is not recommended for women attempting to conceive. In women experiencing difficulties conceiving or undergoing infertility investigations, withdrawal of Diclofenac Sodium should be considered.

Drug interactions with diclofenac sodium include:

• Anticoagulants (e.g., warfarin) (may increase the risk of bleeding- monitor INR closely)
• Other NSAIDs (e.g., ibuprofen) (may increase the risk of gastrointestinal bleeding and ulceration)
• Antihypertensives (e.g., ACE inhibitors, diuretics) (may reduce the effectiveness of blood pressure-lowering medications)
• Corticosteroids (e.g., prednisone) (may increase the risk of gastrointestinal adverse effects)
• Lithium (may increase lithium levels and risk of toxicity- monitor serum levels)
• Methotrexate (may increase the toxicity of methotrexate- monitor for adverse effects)
• CYP2C9 inhibitors (e.g., fluconazole) (may increase diclofenac levels and risk of side effects)
• Cyclosporine (may increase the risk of renal toxicity)
• Antidiabetic agents (e.g., metformin) (no significant interaction but monitor for any changes in blood glucose)

Diclofenac sodium is a powerful medication often prescribed to relieve pain and reduce inflammation. For it to be effective and safe, it must be properly stored. It should be kept at room temperature, preferably between 15°C and 30°C (59°F and 86°F). Heat, moisture, and light should be avoided as they can affect the medication's quality. For this reason, the bathroom is not a suitable place to store diclofenac sodium. It should not be kept in a refrigerator or freezer either, as these temperatures can cause the medication to break down, reducing its effectiveness.Diclofenac sodium should also be kept out of reach of children and pets, as it can cause harm if taken incorrectly or accidentally consumed. Ideally, it should be stored in a safe and secure place, out of sight and reach of others, to prevent such accidents. To ensure optimal effectiveness and safety when taking diclofenac sodium, always follow the storage instructions provided by your doctor or pharmacist. If you have any questions or concerns about storing this medication, consulting with your healthcare provider for guidance is always recommended.